Illustration to show the life cycle
of the schistosome parasite.
Fresh - water snails living in certain tropical regions of the world release the larval forms
of the schistosome parasite, which penetrate the skin, migrate through the body, and develop into adults that lay eggs that cause the disease.
We also did some field work and visited the site
of a schistosome infection that is infecting ducks that live next to the White House!
The stakes are high: more than 70 countries affected by schistosomiasis rely heavily on praziquantel, which usually works after just one dose and against all species
of schistosome worms.
In the early 1970s, I majored in human biology at Brown University in Providence, Rhode Island, where my faculty adviser's research interest was in the biochemistry
of schistosomes.
The data obtained provide a wealth of information on the reproduction biology
of schistosomes and a rich resource for exploitation through basic and applied research activities.
Not exact matches
James Bennett, at the University
of Michigan, studies
schistosomes in Egypt where praziquantel has been used more heavily than anywhere else in the world.
Researchers at the Sackler School
of Graduate Biomedical Sciences at Tufts and Tufts University School
of Medicine (TUSM) have uncovered a mechanism that may help explain the severe forms
of schistosomiasis, or snail fever, which is caused by
schistosome worms and is one
of the most prevalent parasitic diseases in the world.
After observing important similarities between planarians and their disease - causing cousins, Newmark and former postdoctoral fellow Jim Collins (now a professor at UT Southwestern) took the radical step
of applying their knowledge
of planarians to studying
schistosome biology.
As we learn more about how
schistosomes infect their hosts and reproduce inside them, we hope to devise new strategies for controlling these devastating parasites that infect hundreds
of millions
of people in the developing world.
Our results indicate that sma - miR - 277 / 4989 might play a dominant role in post-transcriptional regulation during development
of juvenile worms and suggest an important role in the sexual development
of female
schistosomes.