They noted that confirmation through other studies was needed before such a link could be said to be established, and they cautioned that in the history
of schizophrenia research, many apparent associations had eventually proved spurious or impossible to replicate.
«While a great deal of money has been invested in developing schizophrenia drugs, a similar investment hasn't been made to develop biomarkers that could improve the reliability and consistency of test results,» said Daniel Javitt, MD, PhD, professor of psychiatry and Director of the Division of Experimental Therapeutics at CUMC, Director
of schizophrenia research at the Nathan Kline Institute for Psychiatric Research, and Co-Principal Investigator of the study.
An attitude of gloom pervaded the field
of schizophrenia research for decades, with many scholars insisting that improvement was exceedingly rare, if not unheard of.
«We're interested in determining patients» sleep patterns,» says John Kane, head
of schizophrenia research at Zucker Hillside Hospital in Glen Oaks, N.Y. Kane, who is conducting a Proteus - funded pilot study, says, «For certain mental illnesses, changes in sleep patterns are an early sign that an illness is accelerating.»
Not exact matches
Research finds high percentage
of long - term homeless suffer
schizophrenia, were abused as children.
Danielle A. Schlosser, PhD, Assistant Professor, Department
of Psychiatry; Director
of the Digital Health Core in the Department
of Psychiatry, and Director
of the NIH - funded Digital
Research and Interventions for Volitional Enhancement (DRIVE) lab at UCSF Dr. Schlosser's research program's goal is to design, develop, and investigate neuroscience - informed digital health solutions to improve the lives of people with schizophrenia and dep
Research and Interventions for Volitional Enhancement (DRIVE) lab at UCSF Dr. Schlosser's
research program's goal is to design, develop, and investigate neuroscience - informed digital health solutions to improve the lives of people with schizophrenia and dep
research program's goal is to design, develop, and investigate neuroscience - informed digital health solutions to improve the lives
of people with
schizophrenia and depression.
LifeWay
Research asked three groups
of Protestants — pastors, family members
of people with acute mental illness (severe depression, bipolar disorder, or
schizophrenia), and those with such illnesses — when «psychological therapy» should be used.
The charity Rethink Mental Illness has welcomed a new study into the links between
schizophrenia and dementia, but also called for more
research into the causes
of mental illness.
He also quoted
research which «estimates that, to prevent one episode
of schizophrenia, we would need to stop about 5,000 men aged 20 to 25 years from ever using the drug».
«The evidence suggested that
schizophrenia risk predicts the likelihood
of trying cannabis,» said Dr Suzi Gage,
Research Associate with the MRC Integrative Epidemiology Unit.
Recent
research explores the effects
of a
schizophrenia risk factor (DISC1) and its influence over the onset
of the disease.
People who have a greater risk
of developing
schizophrenia are more likely to try cannabis, according to new
research, which also found a causal link between trying the drug and an increased risk
of the condition.
These characteristics appeared regardless
of whether the people had suffered from depression,
schizophrenia, bipolar disorder, or no disorder at all (Brain
Research, doi.org/cvrpjk).
A damaging chemical imbalance in the brain may contribute to
schizophrenia, according to
research presented at the American College
of Neuropsychopharmacology Annual Meeting in Hollywood, Florida.
What would really help progress this
research is to use genetic variants that predict heaviness
of cannabis use, as it seems that heavy cannabis use is most strongly associated with risk
of schizophrenia.
When I got my first faculty position, at the University
of Texas, I wanted to continue
researching schizophrenia.
Previous
research had found that the children
of women who caught flu while pregnant are more likely to develop
schizophrenia later in life.
He says that seeing
schizophrenia - like anomalies in the brain
of a closely related primate «really enhances the plausibility»
of previous
research that links flu to fetal brain development in humans.
Belger, the director
of the UNC Neurocognition and Imaging
Research Laboratory, and recent UNC graduate student Joseph Shaffer, PhD, compared brain scans from more than 100 people with
schizophrenia against brain scans from people with no psychiatric diagnoses.
New
research is pointing to a different possibility: There may be no adaptive advantage provided by
schizophrenia in and
of itself, but rather from some genes that contribute to the disease.
People who were bullied by siblings during childhood are up to three times more likely to develop psychotic disorders such as
schizophrenia in early adulthood, according to new
research by the University
of Warwick.
Research presented at a Berlin psychiatric conference shows teenage cannabis use hastens onset
of schizophrenia in vulnerable individuals
According to Gur, whose program specializes in
schizophrenia, translational neuroscience requires thoughtful consideration
of the relevance
of basic
research findings to human behavior.
«Part
of the terror
of schizophrenia is that the brain can't properly integrate sensory information, so the world is a disorientating series
of unrelated bits
of input,» says Albright, the Conrad T. Prebys Chair in Vision
Research.
He first began
researching possible autoimmune causes
of schizophrenia in the early 2010s while working at the National Institutes
of Health and published early papers on the subject.
Using the new testing method, the
research group was able to correctly differentiate the samples
of those who had been diagnosed with
schizophrenia from those who had no history
of the disorder.
Further
research showed that fetal mice bred to lack these molecules — like animals lacking MHCI, and like humans with autism or
schizophrenia — undergo inadequate synaptic pruning in some parts
of their brains.
«While further
research is required before this blood test could be clinically available, these results provide evidence regarding the fundamental nature
of schizophrenia, and point towards novel pathways that could be targets for preventative interventions,» Perkins said.
In addition to running his own lab, he directs the Applied Neurotherapeutic
Research Group, a collaborative research initiative funded jointly by SFI and Wyeth, to understand the molecular underpinnings of changes in behavior and to identify new drug targets for diseases such as schizo
Research Group, a collaborative
research initiative funded jointly by SFI and Wyeth, to understand the molecular underpinnings of changes in behavior and to identify new drug targets for diseases such as schizo
research initiative funded jointly by SFI and Wyeth, to understand the molecular underpinnings
of changes in behavior and to identify new drug targets for diseases such as
schizophrenia.
Dr Rachael Panizzo, Programme Manager for Mental Health and Addiction at the Medical
Research Council, added: «This large study provides further evidence
of the complex genetics underlying
schizophrenia.
Working with an international group
of scientists from Cardiff University, Stanford University and Duke University in addition to screening post-mortem brain samples from the Stanley Medical
Research Institute, the scientists are the first to identify a molecular genetic component
of the blood brain barrier with the development
of schizophrenia.
Remarkably, two compounds that seem to exert these neuroprotective effects — both
of them a focus
of intense interest in
schizophrenia research — aren't sophisticated drugs but simple compounds found in nature.
The
research effort he directs focuses on entirely new compounds that might slow the loss
of brain cell connections, which may play a role in
schizophrenia biology.
«We knew this gene's alteration likely contributed to
schizophrenia and we wanted to better understand how,» said Mei, chairman
of the Department
of Neuroscience and Regenerative Medicine at the Medical College
of Georgia at Augusta University, Georgia
Research Alliance Eminent Scholar in Neuroscience and a corresponding author
of the study in the journal PNAS.
► The Broad Institute received a huge donation — $ 650 million, the largest ever made for psychiatric
research — from philanthropist and businessman Ted Stanley, to study the biological basis
of psychiatric diseases such as
schizophrenia and bipolar disorder, Emily Underwood wrote at ScienceInsider.
The model expands the
research toolkit for investigations
of social behaviors and psychiatric diseases like autism and
schizophrenia.
Christianson said the findings set the stage for a large - scale investigation
of the brain circuits that work together to orchestrate responses to social emotional information with the hope that such
research will lead to better treatment for people with conditions marked by aberrant social cognition, such as autism or
schizophrenia.
Carson and his colleagues plan future studies involving PET imaging
of synapses to
research epilepsy and other brain disorders, including Alzheimer's disease,
schizophrenia, depression, and Parkinson's disease.
People with
schizophrenia may now benefit from more effective, tailored treatments and greater self - empowerment, thanks to
research establishing a link between childhood trauma and some
of schizophrenia's most common symptoms.
Nevertheless, the flood
of data stemming from this
research has failed so far to yield truly effective therapies for
schizophrenia, depression, and other disorders, or a truly persuasive explanation
of how brains make minds.
«Childhood trauma link offers treatment hope for people with
schizophrenia: People with
schizophrenia may now benefit from more effective, tailored treatments and greater self - empowerment, thanks to
research establishing a link between childhood trauma and some
of schizophrenia's most common symptoms..»
But with all the effort being put into
researching the disease, he says, «maybe 5 to 10 years from now we will have some idea
of how
schizophrenia works.»
Virologist Robert Yolken
of Johns Hopkins Medical School in Baltimore and psychiatrist E. Fuller Torrey
of the National Alliance for the Mentally Ill
Research Institute in Bethesda, Maryland, have long argued that each
of these factors may stimulate infectious agents that could provoke individuals to develop
schizophrenia as adults.
«I think I can best serve the
research by not being a user - advocate,» he says, heeding a healthy number
of studies that show the drug can precipitate psychiatric illnesses like
schizophrenia and cause people to engage in lethal behavior like jumping off buildings.
In his lecture Blom will mention a number
of examples
of disturbances that in practice are often mistaken for
schizophrenia, and he will explain how empirical scientific
research can contribute to improving care for people with diverse psychotic disturbances.
Scientists
of the Transfaculty
Research Platform «Molecular and Cognitive Neurosciences» (MCN) at the University
of Basel and the Psychiatric University Clinics have now described a network
of genes that controls fundamental properties
of neurons and is related to working memory, brain activity and
schizophrenia.
Yet
research has consistently failed to directly link parenting to the onset
of schizophrenia, although numerous investigations suggest that intense familial criticism may hasten its relapse.
The Broad Institute, a collaborative biomedical
research center in Cambridge, Massachusetts, has received a $ 650 million donation from philanthropist and businessman Ted Stanley to study the biological basis
of diseases such as
schizophrenia and bipolar disorder.
Although effective new drugs based on such
research may be decades away, near - term payoffs could include ways
of identifying teens at risk
of developing
schizophrenia early on, or tools that help physicians better manage their patients» medications, added Steve McCarroll, director
of genetics
research at Broad.
The new findings, published 21 January in
Schizophrenia Research, support an alternate theory: Autism and
schizophrenia are independent outcomes
of the same genetic syndrome.