This project depends upon our ability to obtain DNA - containing specimens from at least 25 dogs with a confirmed diagnosis
of sebaceous adenitis, in addition to specimens from unaffected dogs, preferably healthy close relatives.
Participation Requirements: Dogs must have a confirmed diagnosis
of Sebaceous Adenitis in addition to normal parents or siblings.
Not exact matches
Other less common possibilities for flaky skin in dogs include ichthyosis,
sebaceous adenitis or primary seborrhoea sicca — all
of which are primary keratinisation defects
of the skin.
Sebaceous adenitis is an inflammatory disease of the sebaceou
Sebaceous adenitis is an inflammatory disease
of the
sebaceoussebaceous glands.
Purpose
of Study:
Sebaceous adenitis is a skin disease that is seen in many breeds but most prevalent in the Standard Poodle, Havanese, Akita, and English Springer Spaniel.
Little is known about the mode
of inheritance; that is, whether they are simple as progressive retinal atrophy and
sebaceous adenitis are in some breeds or are, like hip dysplasia, a complex association
of many genes.
Granulomatous
sebaceous adenitis: a disease
of sebaceous (sweat) skin glands characterized by reactive tissue growth and autoimmune destruction
of the
sebaceous glands.
Tests that are available now are x-rays to detect displaced or malformed hips, elbows, and knees; eye tests for progressive retinal atrophy; a biopsy for
sebaceous adenitis; a blood test for hypothyrodism and vonWillebrand's disease (a bleeding disorder); the BAER (1) test for deafness; and a smattering
of other tests that aid in detecting breed - specific diseases.
Inherited diseases or structural problems such as hip dysplasia, glaucoma,
sebaceous adenitis (a skin disease), various heart ailments, and more tend to affect many breeds
of dogs.
Also, Poodles may suffer from hip dysplasia,
sebaceous adenitis, Cushing's disease, Addison's disease, and gastric dilatation - volvulus, so be aware
of the signs for those conditions in your Clumberdoodle as well.
Vitamin A has been advocated for
sebaceous adenitis but seems to be fading out
of popularity with the advent
of other oral treatments (see below).
Certain breeds such as Standard Poodles, Vizslas, Akitas and Samoyeds suffer from deep pyoderma or infection as a result
of the condition
sebaceous adenitis.
The Poodle Club
of America Foundation has provided funding to support a research project under the direction
of principal investigator Niels C. Pedersen, «Determining whether risk for
sebaceous adenitis of Standard Poodles is associated with a specific DLA class II genotype.»
Pedersen, N.C., Brucker, L., Green Tessier, N., et al. «The Effect
of Genetic Bottlenecks and Inbreeding on the Incidence
of Two Major Autoimmune Diseases in Standard Poodles,
Sebaceous Adenitis and Addison's Disease.»
Sebaceous adenitis is one
of those puppy and dog skin conditions that is often seen in specific breeds — especially Poodles and Akitas.
They are generally rather healthy, but they too can develop certain medical conditions such as hip dysplasia (with a score
of fair or better), elbow dysplasia, hypothyroidism, and von Willebrand's disease, Addison's Disease, Gastric Dilatation - Volvulus, Cushings Disease (Hyperadrenocorticism), Epilepsy, Hypothyroidism, Legg - Perthes Disease, Patellar Luxation, Optic Nerve Hypoplasia,
Sebaceous Adenitis (SA) and Von Willebrand's Disease.
For example, poorly - bred Dalmatians can be unilaterally or bi-laterally deaf; Newfoundlands can have heart problems; Basenjis are susceptible to Fanconi syndrome, a kidney disease; Akitas and Poodles are among a handful
of breeds susceptible to
sebaceous adenitis, a skin disease; Collies may have Collie eye anomaly; toy breeds are susceptible to patellar luxation (slipping kneecaps); and some breeds have a higher frequency
of particular types
of cancer.
For example, if both parents
of your Standard Poodle have certificates proving they were tested and cleared
of hereditary eye diseases, hip dysplasia, thyroid disease, and
sebaceous adenitis, your Standard Poodle has less risk
of developing those conditions.
OFA costs range from $ 15 for
sebaceous adenitis tests to $ 40 for combined readings
of hip and elbow radiographs and do not include the veterinary fee for taking the radiographs.
The Standard Poodle is the most likely
of all breeds to develop a serious skin disease called
sebaceous adenitis.
Akitas are prone to various skin disorders, some
of an autoimmune nature, such as
sebaceous adenitis.
Some
of them are prone to a skin disease (
sebaceous adenitis) and a few may have retinal atrophy (PRA), dry eye, or cherry eye.