The combined activity
of second messengers and enzymes (lipases, kinases, phosphatases and GEFs) yields a physiological response.
The researchers assume that this is the signal that sparks off the response: The bacterial cell now boosts the synthesis
of a second messenger, which in turn stimulates the production of an adhesin that firmly anchors the bacteria on the surface within a few seconds.
Catecholamines signal through the β2 - adrenergic receptor by promoting production
of the second messenger adenosine 3 ′, 5 ′ - monophosphate (cAMP).
The current study revealed that amlexanox exerts its effects through a specialized type of fat cell by increasing the level
of a second messenger molecule called cAMP.
Not exact matches
11:19), Jesus is apparently referring to himself in some sense as a special
messenger of God, but there is no suggestion here
of a supernatural and apocalyptic
second coming.
He can send his commandments down from Mt.
Second Floor and have his
messenger Moses Dicker smash the tablets at the feet
of the idolators and the lobbyist and the moneychangers amd the hospital and teacher's unions.
On April 30, if all goes well, after running out
of fuel to fight off orbital decay NASA's long - running
MESSENGER spacecraft will end its mission to Mercury by crashing into the planet's surface at nearly 4 kilometers per
second.
In his
second semester, he started doing research in three different labs, including that
of Carolyn Decker, a molecular biologist who was investigating how the cell controls gene expression through the destruction
of messenger RNA.
This marks the
second time in four years that the chemistry Nobel has been awarded to someone working with x-ray crystallography; in 2006 Roger Kornberg took the prize for detailing the structure
of messenger RNA, which is the molecule that carries the information the ribosome uses to build proteins, such as insulin or hemoglobin.
The recent explosion
of green fluorescent protein (GFP) based sensors
of pH, halides, proteases, kinases, G proteins, and many
second messengers (including Ca2 +, cAMP, cGMP, nitric oxide, and IP3) have provided important tools for the design
of screening assays.
In the
second phase, the reduction in
messenger RNA causes less
of the AtGRP7 protein to be formed.
DGKζ, a lipid kinase, phosphorylates the
second messenger DAG, terminating DAG - mediated activation
of RasGRP1 and PKC - θ, whereas Cbl - b, an E3 ubiquitin ligase, facilitates ubiquitination and subsequent degradation
of the p85 subunit
of PI (3) K. Previous studies have evaluated numerous aspects
of T cell biology in the two models (16 — 18, 25, 38), but the signaling and functional effects
of DKGζ deficiency and Cbl - b deficiency in T cells had not been directly compared.
On October 6, 2008, NASA's
MESSENGER spacecraft made its
second of three flybys around Mercury, to be undertaken before it settles into orbit around the innermost planet in March 2011.
Two methods published by BMG LABTECH describe (1) real - time detection
of Gs and Gi signaling and (2) detection
of GPCR
second messengers in living cells.
These versatile tools enable quantitative, functional imaging
of molecular interactions, protein activities or
second messenger concentration in single living cells.
This process is mediated by
of a diverse set
of signaling molecules, i.e. enzymes,
second messengers, scaffolds and transcription factors.
This has been used to create reporters for
second messengers by using protein (domains) that undergo a conformational change upon binding
of e.g. Ins (1,4,5,) P3, calcium or cAMP.
The nervous system can make very quick changes in a fraction
of a
second by sending electrical impulses through the spinal cord to the muscles, or it can make slow changes by sending chemical
messengers, called hormones, into the blood to reach the tissues and the organs.
He's wearing an eyepatch and carrying a bundle
of papers, which he hands over to Downey's character like a
messenger handling the afterthought
of the
second half
of the script.
The
second day
of this festival, Kukur Puja, also known as Diwali, worships dogs, who are believed to be
messengers of the God
of Death.
The date honors the launch
of the US Army K - 9 Corps program in 1942 and the memory
of the brave Belgian Sheep Dogs, Doberman Pinschers, Eskimo dogs, Collies, German Shepherds and Malamutes who trained to become
messengers, sentries and scouts during the
second World War.
Firstly, I have no need
of Mann's code (this isn't my field) and secondly, I have only your word about the
second issue — this is your dispute, not mine and I am certainly not your
messenger boy.
The social
messenger Telegram has closed the
second round
of its token sale, attracting $ 850 million.
Messengers of the «avoid using an objective & # could do a better job
of explaining themselves, no doubt, and those on the opposing side should avoid building up drama, leading with criticism, and offering split -
second «fact & # interpretation.