Sentences with phrase «of sequencing runs»

The MinION replaces the conventional model of «sequence followed by analysis to final result» with instant access to data before the completion of a sequencing run.

Not exact matches

What's more, retirees who are drawing on their investments to support themselves run a market «sequence of return risk.»

In the third sequence of ads, DJ Khaled has launched a personal training program in his crazy - fancy mansion where a group of people run on a golden treadmill.

But the biggest threat to a successful retirement is a long run of bad returns in the early years, otherwise known as sequence of returns risk.

The periods run in a natural sequence around the starting point of price stability.

Evolution is not testable — Every new fossil dug up, every genome sequenced, every new species discovered, every new simulation run is a test of evolutionary theory.

Only in these two places in the Christian Bible do we find this sequence of verbs: he runs, falls on his neck, and kisses him.

The key sequence at the end: Georgia blocked a 27 - yard Oklahoma field goal on the Sooners» opening possession of double OT, then got a 27 - yard touchdown run from Sony Michel to win it.

That was the case right up until an almost miraculous block of a Gareth Bale shot during a terrifying sequence of Real attacking nearly found the back of the net, finally letting Atlético launch forward on the counter — and Juanfran found Carrasco running for the far post, drilling a low cross to the Belgian that got emphatically fired home to level the scoreline and send Atlético fans all over the world into rapturous joy.

Once he recorded the offstage voice for the game sequence in the Broadway production of Damn Yankees, and in a movie called The Babe Ruth Story Allen's voice described Ruth's then remarkable 60th home run.

Similarly, Fellaini looked as influential as he did during United's previous best run under Van Gaal where they beat Tottenham Hotspur, Liverpool and Manchester City in a six - game sequence of consecutive wins last season, during which the Belgian was used to bully opposing right - backs and midfielders to great effect.

Saturday's 1 - 1 draw with free - falling Blackpool at home stretched their winless run to four in the league, having won just one of their last nine Premiership matches in a destructive sequence which has destroyed any hope they had of competing in the Champions League for a second consecutive season.

When trying to predict the results of football matches, do you study the form or do you expect long running sequences to come to an end?

The high point of that sequence was Wednesday's 5 - 0 rout of 10 - man Heerenveen, which saw Siem de Jong run in a hat - trick after Heerenveen goalkeeper Brian Vandenbussche was sent off in the third minute.»

Barcelona have a W7 D1 L2 record from that sequence and both defeats in that run of games did happen out on the road for them.

Owen Coyle will have no doubt hand - picked plenty of positives from a festive period which didn't exactly reap may rewards in terms of points, though even the potential manager of the season will have his fair share of concerns regarding his team's current frame of mind following ta three - match sequence without registering a win in the league, a run that probably wasn't remedied by a 2 - 0 FA Cup third - round victory over Conference side York City simply because it was scruffy and very fortuitous, not to mention required Coyle to draft in his big boys in the dyeing embers of the game.

Barcelona are running on a 13 match unbeaten streak against Atletico Madrid, winning ten of those and that is their best ever sequence against the Madrilenian opposition.

The causal sequence, as I understand it, runs as follows: (1) Inadequate regulation of the financial sector leads to (2) crisis in the financial sector which leads to (3) crisis in the whole economy which leads to (4) falling tax revenues which leads to (5) a bigger budget deficit.

Soil samples are run through powerful machines to have their microbes genetically sequenced, drones are flying overhead taking hyperspectral images of the crops, and soon supercomputers will be crunching the massive volumes of data collected.

The man responsible for one of the original sequences of the human genome as well as the team that brought you the first living cell running on human - made DNA now hopes to harness algae to make everything humanity needs.

Through detailed genome comparisons, sequence - alignment algorithms and other bioinformatics tools run on Los Alamos computers, the Los Alamos team identified features that differentiate among F. tularensis and other novel clinical and environmental Francisella isolates, providing a knowledge base for comparison of new sequences from clinical or environmental surveys.

«It's also able to run the latest in cutting - edge genetic analysis called Next Generation Sequencing, which a lot of researchers are currently utilizing.

The result was an extremely high - throughput sequencing protocol that, in a single run, can cover portions of the genomes of over 50,000 microbial cells (2).

Each particle has a 50 - 50 chance of being measured as spin - up or spin - down; the sequence of clicks would be a random series of +1's (upper counter) and -1's (lower counter), averaging out over many runs to an equal number of clicks from each detector.

Time sequence of frames, running top to bottom, suggests how some «seed photons» from spontaneous annihilation of a few Ps atoms will stimulate subsequent Ps annihilations, resulting in a pulse of 511 keV gamma rays

In a random sequence like tossing a coin, a run of one event (heads) makes people think the other outcome (tails) is due next; this is known as the «gambler's fallacy».

Finally, they ran the results through a software program that combed through many gene sequences simultaneously, comparing each one with the sequences of known viruses stored in online databases.

But intensive DNA sequencing of four species of this alga did not turn up any plastid; nor did the alga's main genome have any of the genes typically needed to keep a plastid genome running smoothly.

If we could get all of that material out of the deep freeze and run it through the sequencing machine, we would find the answer.

«We detect changes in the sequence of code the program runs, ones often introduced by malicious programs.

The software is designed to run on the MinION, an instrument the size of a credit card that pulls in strands of DNA through its microscopic pores and reads out sequences of nucleotides, or the DNA letters A, T, C, G.

When the promoter upstream of the GFP gene was activated, the RNA polymerase ran headfirst into the termination sequence, stopped reading the DNA, and didn't produce the fluorescent protein.

Searfoss estimates that only about 5 percent of a commander's launch training is running through normal sequences — the rest of the time is spent learning how to cope with emergencies.

Most sequencing technologies tick off the sequence of DNA's four chemical letters — A's, G's, C's, and T's — by linking fluorescent molecules to the letters and the progression of colors produced by running through the sequence of each DNA strand.

DNA samples were then pooled at an equimolar ratio and run on a Roche / 454 GS FLX using standard chemistries at the University of Pennsylvania's DNA Sequencing Facility.

(F, G, H) The number of unique sequences within the subsets which share exact runs of CDR3 residues are plotted on the y - axis against runs of increasing CDR3 length on the x-axis for (F) B9, (G) A14 and (H) B21 at the time points indicated in the legend.

The CDR3 sequences of the subsets were then analyzed for the frequencies of residues that matched to those found in the mature CDR3 at the same position and the number of unique reads where sequential CDR3 residues (runs) matched to the mature CDR3 sequence.

The revised age model for the top 30 m of MAL05 - 1C (Fig. 4) was generated using 15 radiocarbon ages (7) and the latest high - precision YTT age estimate of 75.0 ± 0.9 ka (4) in a Bayesian P - Sequence depositional model (37), run in OxCal version 4.1 (38) with outlier analysis (39) and interpolation at 0.5 m intervals.

These are displayed in the form of «time lines» running across the screen and indicating the length of each sequence.

And they're just these beautiful, clever things where one card can let you run through this whole very complicated sequence with dozens of levers.

The difficulty in measuring such a small increment in chromosome 21 DNA concentration has recently been overcome with the use of massively parallel genomic sequencing.20 This technique can identify and quantify millions of DNA fragments in biological samples in a span of days.23 Three cohort studies have shown the feasibility of using the technique to identify fetuses with trisomy 21 by analysis of maternal plasma DNA.24 25 26 The sample numbers studied were small because, typically, only a few samples could be analysed in each sequencing run.

Amplicons were sequenced on a multiplexed 454 - FLX - Titanium pyrosequencing run at the Human Genome Sequencing center at Baylor College of Medicine.

The authors of this scientific report explain further that comparing aligned sequences relative to their respective genomes using BowTie version 0.12.7 served two purposes: (i) To obtain unaligned reads for further analysis; and (ii) to observe variation in the numbers of both aligned and unaligned reads across different runs, experiments and organisms.

When you are looking for potential SNPs, particularly without a reference genome, you run the risk of identifying sequence differences between duplicated sequences rather than differences between individuals.

After this course you should be able to: - Prepare libraries from genomic DNA for amplicon or whole genome approaches to nanopore sequencing - Run ONT devices and assess sequencing performance during a run - Understand the basics of ONT data handling and analysis - Analyse and interpret ONT amplicon data and whole genomic data from bacterial sampRun ONT devices and assess sequencing performance during a run - Understand the basics of ONT data handling and analysis - Analyse and interpret ONT amplicon data and whole genomic data from bacterial samprun - Understand the basics of ONT data handling and analysis - Analyse and interpret ONT amplicon data and whole genomic data from bacterial samples

Introduction to ONT devices and latest technology Wet lab training and best practices for sample quality and library preparation for Nanopore sequencing Running MinKNOW and real - time sequencing data handling Introduction to basecalling and analysis tools (ONT and opens source) for analysis of ONT data

It is constructed with a JavaScript - based algorithm; thus, it wholly runs on the client - side so that large amounts of sequencing data do not need to be uploaded to the server.

AmpliSeq HiQ libraries for sequencing were prepared on the Ion OneTouch 2 system, quantified using the Qubit 2.0 fluorometer (Life Technologies, Thermo Fisher Scientific, Waltham, MA, USA) and massive parallel sequencing (MPS) was subsequently performed on the Ion Proton System utilizing a PI chip (Life Technologies, Thermo Fisher Scientific, Waltham, MA, USA), with 2 or 3 samples (in cases of family trio) loaded per run.

Results: MinION correctly identified pathogens without culture and, among 55 acquired resistance genes detected in the cultivated bacteria by Illumina sequencing, 51 were found by MinION sequencing directly from the urines; with three of the four failures in an early run with low genome coverage.

Genomes that have been sequenced as part of a GWAS can be run through PrediXcan to generate a gene expression level profile, which is then analyzed to determine the association between gene expression levels and the disease states or the trait of interest being studied.