Sentences with phrase «of sickle cell anemia»

But I have a couple of good Chem books now, including Linus Pauling; whom I once had the privilege of listening to; in a lecture on the molecular causes of Sickle cell anemia; which is a problem of molecular shape (Haemoglobin).

He chose to incorporate his medical condition of sickle cell anemia, an illness he had been living with his whole life.

Currently with St. Jude Children's Research Hospital, Cunningham has led research that expands medical understanding of sickle cell anemia and thalassemia.

He was best known for his work, with Linus Pauling, on the molecular basis of sickle cell anemia.

«The one thing that I think that is useful is maybe when people write knockout papers they might describe the housing conditions in more detail,» says Chris Paszty, scientific director at the biotech company Amgen, Inc., headquartered in Thousand Oaks, Calif., who as a postdoctoral researcher at Lawrence Berkeley National Laboratory developed a mouse model for the study of sickle cell anemia.

Tim Townes of the University of Alabama, Birmingham, and his colleagues wondered whether iPS cells might prove useful in a mouse model of sickle cell anemia.

In today's online edition of Science, researchers describe using induced pluripotent stem (iPS) cells to alleviate symptoms of sickle cell anemia in mice.

Enzymatic amplification of beta - globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia

The new model, which is a scaled - down version of an earlier numerical model by Shaqfeh and colleagues that provided the first large - scale, quantitative explanation of the formation of the layer, can predict how blood cells with varying shapes, sizes, and properties — including the crescent - shaped cells that are the hallmark of sickle cell anemia — will influence blood flow.

«The study indicates that screening for silent strokes in children starting school can lead to early detection and prevention of recurrences as well as reduction in other complications of sickle cell anemia such as acute painful episodes and acute chest syndrome.

It could be a more complicated version of the familiar case of sickle cell anemia: having two mutant copies of a certain gene causes the disease, whereas having only one mutant copy provides protection against malaria.

The overall benefit of sickle cell trait outweighs the cases of sickle cell anemia.

Individuals who carry sickle cell trait (the unexpressed mutation of sickle cell anemia) are more likely to survive malaria and therefore, the trait is actually protective against a disease that is endemic in many parts of the world.

Not exact matches

Emmaus Medical CEO Dr. Yutaka Niihara spent much of his career developing Endari, a recently approved FDA drug to treat sickle cell anemia.

The company's genome kit, which was named «Invention of the Year» by Time magazine in 2008, tests for 36 recessive disorders, including sickle cell anemia and cystic fibrosis.

That said, sickle - cell anemia, cancer, malaria, ebola, etc. are all pieces of the fabric of life, a part of the design, and all of their operations are manifestations of the physics of our universe which allow for our wonderful biotic world to exist.

My son had to be screened for sickle cell anemia when he ran track at college, even though it was patently obvious that he was not in any remote danger of having it.

Although most states require only a handful of tests, a panel of experts convened by the U.S. Department of Health and Human Services and the March of Dimes recommends newborns be screened for 30 genetic disorders, including hypothyroidism, cystic fibrosis, and sickle cell anemia.

The mutation that causes sickle cell anemia most probably became dominant because it gave some protection against malaria — but at a cost of its own.

As early as the first trimester, doctors can take a sample of placental tissue (chorionic villus sampling, or CVS) to detect whether a baby has the genes that would lead to sickle cell anemia or sickle cell trait.

Sickle cell anemia is caused by a genetic mutation that leads to «sickling» of the red blood cells.

When two individuals with sickle cell trait mate with each other and produce children, one quarter of the children will get a «double dose» of the trait and, therefore, suffer from sickle cell anemia.

Examples of recessive disorders: sickle cell anemia, Tay - Sachs, phenylketonuria (PKU).

Examples of disorders screened are cystic fibrosis, sickle cell anemia, congenital adrenal hyperplasia (enlarged adrenal glands), maple syrup disease, and many more.

Choose an obstetrician or health care provider Interview potential doctors Contact health insurance company about coverage Start and pregnancy and birth budget Discuss financial effects of pregnancy and baby with partner Stop smoking Stop drinking Stop using street drugs Talk to your physician about any prescription medications Drink at least 8 glasses of water every day Visit the doctor at least once per month or every 4 weeks Do not dye or perm hair Stop drinking coffee and other caffeinated beverages Exercise daily Start taking prenatal vitamins Eat foods rich in folic acid Eat iron rich foods Increase daily intake of whole grains, fruits and vegetables Nap as much as possible as fatigue is common Eat fish with low levels of mercury no more than 2 days per week Do not eat undercooked meats Do not eat unpasteurized dairy producs Do not eat cold cut deli meats Allow someone else to clean out the kitty litter, if applicable Limit exposure to chemicals Try to limit stress and tension Complete all prenatal tests — HIV, Chlamydia, Gonorrhea, Anemia, Blood Typing, Sickle Cell Anemia, Urine Screening and Rubella.

Although most people only get transfusions once or twice in their lives (if at all), individuals with conditions like sickle - cell anemia require consistent blood transfusions of red cells.

In people with sickle cell anemia, molecules of sickle hemoglobin clump together and form long rods that cause red blood cells to become rigid and take on a sickle shape.

Harvard Stem Cell Institute (HSCI) scientists have taken the first steps toward developing a treatment that would make bone marrow — blood stem cell — transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and ACell Institute (HSCI) scientists have taken the first steps toward developing a treatment that would make bone marrow — blood stem cell — transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and Acell — transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and Acell anemia, thalassemia, and AIDS.

Alan Flake at The Children's Hospital of Philadelphia (CHOP) in Pennsylvania is planning a similar clinical trial of maternal stem cells in fetuses with sickle cell anemia, a painful, debilitating disease that often shortens life.

«While sickle cell newborn screening is standard in the U.S., very few infants are screened in Africa because of the high cost and level of skill needed to run traditional tests,» says Dr. Little, Director of the Adult Sickle Cell Anemia Center, UH Seidman Cancer Center and Associate Professor at the School of Medsickle cell newborn screening is standard in the U.S., very few infants are screened in Africa because of the high cost and level of skill needed to run traditional tests,» says Dr. Little, Director of the Adult Sickle Cell Anemia Center, UH Seidman Cancer Center and Associate Professor at the School of Mediccell newborn screening is standard in the U.S., very few infants are screened in Africa because of the high cost and level of skill needed to run traditional tests,» says Dr. Little, Director of the Adult Sickle Cell Anemia Center, UH Seidman Cancer Center and Associate Professor at the School of MedSickle Cell Anemia Center, UH Seidman Cancer Center and Associate Professor at the School of MedicCell Anemia Center, UH Seidman Cancer Center and Associate Professor at the School of Medicine.

The primary cause of anemia is iron deficiency, but it can co-occur with other conditions, such as malaria and genetic disorders like sickle cell.

According to NHLBI, sickle cell anemia is the most common form of sickle cell disease, a serious disorder in which the body makes sickle - shaped red blood cells.

The findings suggest that the presence of sickle cell trait may explain, at least in part, prior observations of greater doses of anemia medications administered to African - American dialysis patients relative to Caucasian patients.

The stroke was just one complication of sickle - cell anemia, the hereditary disease that has haunted her since infancy.

Patients with sickle cell trait received about 13 % more of the medications used to treat anemia than other patients to reach the same level of hemoglobin.

Many of them were babies, and a few suffered from the hematologic disorders that have been the focus of Daley's research — diseases like Fanconi's anemia, thalassemia, sickle - cell anemia, and childhood leukemias.

Other ongoing stem cell trials are targeting blood disorders like aplastic anemia, leukemia, lymphoma, and, of course, sickle - cell disease.

Stem cell treatments are already a reality for diseases of the blood, such as leukemia and sickle - cell anemia (like Paizley's), and for tissue repair of the skin and the cornea.

Only a handful of states have outlawed discrimination based on genetic testing, and most laws are aimed at specific tests, such as one for sickle cell anemia.

On the other end of the spectrum are Mendelian diseases such as cystic fibrosis and sickle - cell anemia, which are caused by abnormalities to a single gene.

You made a name for yourself by curing mice of sickle - cell anemia.

Vanderbilt - led research, as part of an international, multicenter trial, found regular blood transfusion therapy significantly reduces the recurrence of silent strokes and strokes in children with sickle cell anemia who have had pre-existing silent strokes, according to study results released today in the New England Journal of Medicine (NEJM).

Silent strokes are frequent in sickle cell anemia (the most common form of sickle cell disease), occurring in approximately 3 percent of school - age children with the disease, and can cause poor school performance and limit performance of complex tasks.

Given the positive findings of the study, DeBaun and other authors of the study recommend that children with sickle cell anemia have a surveillance MRI, preferably without sedation, by the beginning of elementary school.

Over the next few years, similar maternal blood tests could detect hundreds of diseases caused by chromosome abnormalities or mutations, including cystic fibrosis, sickle cell anemia, Tay - Sachs disease, and genetic deafness and blindness.

The results of this trial will make a difference to children with sickle cell anemia and their families,» said Deborah Hirtz, M.D., program director at the National Institute of Health's National Institute of Neurological Disorders and Stroke (NINDS).

Because the deformation of red blood cells is a key factor in the Fåhræus - Lindqvist layer, its properties are altered in diseases, such as sickle cell anemia, that affect the shape and rigidity of those cells.

A number of new clinical trials aim to take cells from a patient, such as blood cells or immune cells, edit them and transfer them back with new power to undermine diseases like cancer or sickle cell anemia.

Along with his colleagues, Shaqfeh has now created the first simplified computer model of the process that forms that layer — a model that could help to improve the design of artificial platelets and medical treatments for trauma injuries and for blood disorders such as sickle cell anemia and malaria.

A child of parents who each possess one copy of the sickle - cell trait has a one - in - four chance of inheriting both sickle - cell alleles — and thus getting sickle - cell anemia.