Sentences with phrase «of signal transducer»

Activation of Signal Transducer and Activator of Transcription 1 (STAT1) Is Not Sufficient for the Induction of STAT1 - dependent Genes in Endothelial Cells: COMPARISON OF INTERFERON --LCB- gamma -RCB- AND ONCOSTATIN M

Not exact matches

Gold nanoparticles provide bigger surface area for the affinity interactions between the antibody - antigen and thus enhance the translated signal, while the antifouling molecules help to resist the non-specific adsorption of unwanted proteins from serum onto the transducer surface.

The STAT3 protein - it stands for «signal transducer and activator of transcription 3» - is a suspected factor in the relapse of nearly 40 percent of children with AML.

Serving as the acoustic indicator of drug delivery dosage, the microbubble emission signal y (t) is used to find the expected controller output u (f) which is fed back to help control ultrasound transducer transmission.

STAT3 (signal transducer and activator of transcription 3) is a protein that activates the transcription of genes in response to IL - 6, a signaling protein released by cells in response to injury and inflammation.

The so - called Signal Transducers and Activators of Transcription, or STATs, are key components of many different signalling pathways.

Intra - and intermolecular signal transduction mechanisms in membrane - embedded (photo --RRB- receptor / transducer complexes are studied using the photoreceptor / transducer complex NpSRII / NpHtrII, which is responsible for the photoactive behavior of the halophilic archaeon Natronomonas pharaonis.

Right: Light induced EPR signal changes for spin labels bound to positions 159NpSRII (green), 78NpHtrII (red) and 100NpHtrII show the transfer of the signal from the receptor NpSRII to the transducer NpHtrII occurring during the M photocycle intermediate monitored at 400 nm.

A novel disrupter of telomere silencing 1 - like (DOT1L) interaction is required for signal transducer and activator of transcription 1 (STAT1)- activated gene expression.

Signal Transducer and Activator of Transcription - 5 Mediates Neuronal Apoptosis Induced by Inhibition of Rac GTPase Activity.

My Honours project focused on genetically validating the Signal Transducer and Activator of Transcription 3 (STAT3) protein as a therapeutic target by using a novel transgenetic mouse model in which a short hairpin RNA directed against STAT3 can reversibly be induced by the administration of doxycycline.

Rho family GTPase inhibition reveals opposing effects of mitogen - activated protein kinase kinase / extracellular signal - regulated kinase and Janus kinase / signal transducer and activator of transcription signaling cascades on neuronal survival.

Signal transducer and activator of transcription - 5 mediates neuronal apoptosis induced by the inhibition of Rac GTPase activity.

G proteins: transducers of receptor - generated signals.

The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections.

Further, we identified a role for ABL kinases in promoting the expression of multiple pro — bone metastasis genes such as AXL (which encodes a receptor tyrosine kinase), IL6 (which encodes interleukin - 6), MMP1 (which encodes matrix metalloproteinase 1), and TNC (which encodes tenascin - C) through TAZ - and signal transducer and activator of transcription 5 (STAT5)-- mediated signaling.

Abbreviations: ASC, apoptosis - associated speck - like protein containing a caspase - recruitment domain; ATM, adipose - tissue - resident macrophage; BAT, brown adipose tissue; CCR2, CC chemokine receptor 2; CHOP, C / EBP (CCAAT / enhancer - binding protein)- homologous protein; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; ER, endoplasmic reticulum; GPCR, G - protein - coupled receptor; HIF, hypoxia - inducible factor; IFNγ, interferon γ; IKK, inhibitor of nuclear factor κB kinase; IL, interleukin; IRS - 1, insulin receptor substrate - 1; JNK, c - Jun N - terminal kinase; LDL, low - density lipoprotein; Ldlr, LDL receptor; LXR, liver X receptor; MCP - 1, monocyte chemoattractant protein 1; miRNA, microRNA; mTOR, mammalian target of rapamycin; NAFLD, non-alcoholic fatty liver disease; NF - κB, nuclear factor κB; NLRP3, NLR (nucleotide - binding - domain - and leucine - rich - repeat - containing) family, pyrin - domain - containing 3; oxLDL, oxidized LDL; PKR, double - stranded RNA - dependent protein kinase; PPAR, peroxisome - proliferator - activated receptor; STAT6, signal transducer and activator of transcription 6; SVF, stromal vascular fraction; TLR, Toll - like receptor; TNFα, tumour necrosis factor α; UPR, unfolded protein response; WAT, white adipose tissue

The LIM / Homeodomain Protein Islet1 Recruits Janus Tyrosine Kinases and Signal Transducer and Activator of Transcription 3 and Stimulates Their Activities

377/11: 00 Signal transducer and activator of transcription 2 (STAT2) deficiency is a novel disorder of mitochondrial fission.

Antibody staining also shows increased phosphorylation of the Nodal signal transducer, Smad2, in lefty2 mutant embryos as compared to wild - type embryos (Author response image 1)(Dubrulle et al. 2015; Schier 2009).

Dietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PANC - 1 cancer cells.