Sentences with phrase «of signal transduction»

CD45 is a pan-leukocyte protein with tyrosine phosphatase activity involved in the regulation of signal transduction in hematopoiesis.

Roberto Villasenor (Zerial, MPG)-- «Regulation of signal transduction by endosomal EGFR distribution» (2012)

Klemke's interests, and what he envisions to be the future of signal transduction research, is finding which of these signals are active — which are phosphorylated and dephosphorylated, for instance — during cancer cell metastasis.

Understanding the nature of this intrinsic activity will require integrating knowledge from cognitive and systems neuroscience with cellular and molecular neuroscience where ion channels, receptors, components of signal transduction and metabolic pathways are all in a constant state of flux.

An important one of these is its role as a natural inhibitor of signal transduction by hedgehog (a hormone involved in morphogenesis).

My postdoc with Lew Cantley (at Harvard Medical School) opened my eyes to the world of signal transduction.

Numerous proteins and molecules are involved in the process of signal transduction.

«The Cancer Genome Atlas is a really rich and growing database of publicly available data created to help us understand cancer,» said Horvath, who is a program co-leader of the Signal Transduction in Cancer program at the Lurie Cancer Center.

Recent studies such as ours, however, establish protein phosphatases as positive and essential regulators of signal transduction, with remarkable substrate specificity and coordinated activities.

The involvement of NF - κB in β - interferon gene regulation reveals its role as widely inducible mediator of signal transduction.

Aside of the inhibition of signal transduction, on - target repositioning assumes that the targets recognized in nematods, such as mitochondrial respiration and microtubules, are hit in cancer cells [70, 89, 90].

On the one hand, we developed light - switchable compounds as tools for interrogating the dynamics of signal transduction in cells.

Synthetic multivalent ligands as probes of signal transduction.

A simple but realistic mathematical model was created and then used to explore the design principles of signal transduction and transport receptors.

With refinement of signal transduction components, stronger and more specific signaling pathways may be possible.

We have identified three classes of signal transduction mechanisms that may be mediated or modulated by NG2.

Several projects in the area of signal transduction, fluorescent proteins engineering, optogenetics and advanced microscopy are available.

COLQ encodes the collagenous tail of acetylcholinesterase, the enzyme responsible for termination of signal transduction in the NMJ.

During the early years of my PhD studies, I was very fascinated by the exciting discoveries in the field of signal transduction, in particular how receptor tyrosine kinases are activated to transmit their signals and how protein complexes are formed through defined protein folds (domains) interacting with specific cellular targets.

Biophysical and cell biological studies are carried out in conjunction with measurements of cellular activities so as to determine what features are critical for the initiation and regulation of signal transduction.