Sentences with phrase «of signaling complexes»

Control of T cell signaling occurs through both positive and negative regulation, as well as through the actions of molecular scaffolds that contribute to the formation of signaling complexes.
Dimers are grouped in threes to form larger units of the signaling complex, called trimers of dimers.

Not exact matches

The simplicity allows traders to render quick decisions about their signals without getting a bunch of complex and confusing information.
Security regulators are sending out signals that they intend to step up review of distribution of complex financial products, such as variable annuities and equity - linked instruments...
Sending a signal requires maintaining the order of the connection in a complex process, because a signal depends on a whole series of steps having meaning.
At the end of the year I concluded that a group of people can not regularly gather for what they feel to be religious purposes without developing a complex network of signals and symbols and conventions — in short, a subculture — that gains its own logic and then functions in a way peculiar to that group.
The uncertainty surrounding reporting laws may not only reflect complex relations between church and state; they may also signal uncertainty about the practice of confidentiality in the church.
Almost helpless two years ago, they are suddenly one of the best teams in football, and the reason, simply stated, is Van Brocklin, a pro quarterback since 1949, and one of the few signal callers left in this complex, demanding business who still calls his own signals.
The experiments revealed that the creation of a wound generates a complex series of calcium signals in the surrounding tissue:
In complex wound management, we think a lot about what the signaling pathways are and what factors can be involved and what kind of things we could do to improve things.
One theory — the complex contagion theory — posits that costly behaviors (like going for an exhausting run) require a lot of signals from a lot of people.
When muscle injury occurs, a complex chain of signals prompts the satellite cells to awaken and generate new muscle cells to repair the injury.
Was there a chemical or genetic signal that induced stem cells to create the complex structures of the body and brain?
The birds possess the complex ability of referential communication, which involves signals such as calls, displays and whistles to convey information.
In two star - forming regions of the galaxy, ALMA picked up signals emanating from three complex organic molecules, including dimethyl ether and methyl formate, which had not previously been detected outside our own galaxy.
The nonredundant protein sets of flies and worms are similar in size and are only twice that of yeast, but different gene families are expanded in each genome, and the multidomain proteins and signaling pathways of the fly and worm are far more complex than those of yeast.
Professor Taylor, who co-ordinated the research, says: «Our findings provide the very first insight into how biochar stimulates plant growth — we now know that cell expansion is stimulated in roots and leaves alike and this appears to be the consequence of a complex signalling network that is focussed around two plant growth hormones.
«This was the proof that the root hair response to auxin is complex and possibly the result of a signal chain,» the plant scientist explains.
Stanford University researchers studying how the brain controls movement in people with paralysis, related to their diagnosis of Lou Gehrig's disease, have found that groups of neurons work together, firing in complex rhythms to signal muscles about when and where to move.
The researchers examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein inhibits the signal transduction pathway of interferon gamma.
The structure of the SRP signal - sequence complex is determined using x-ray crystallographic methods.
Instead of the conventional signals used in today's technology — bits — which can only be a one or a zero, the new hardware will have to process far more complex quantum entangled states.
The advance improves on a staple of modern computation known as the fast Fourier transform, or FFT, which breaks down a complex signal into its component parts — almost like describing a piano chord by identifying the individual notes that need to be played.
CANTOS grew out of years of ups and downs in the heart disease field, as scientists tried to trace the role of inflammation, a complex cascade of immune signals and various white blood cells that occurs in response to wounds, infections, and more.
It is a product of all five senses (hearing included) interacting in unexpected ways, those sensory signals subject to gross revision as they are integrated by the brain into one complex, sometimes wonderful perception.
This «gain» in current prevents signals from decaying as they travel, and that's a key reason why transistors are crucial for the complex circuits of electronics.
They call this form of activation «non-ligand-dependent,» and in a complex series of biochemical and animal experiments, traced the pathway through which FER's binding to MET inside the cell sets off a cascade of cell - signaling events, all directly connected in prior research with cancer initiation, including RAC1 / PAK1 and SHP2 - ERK.
Cell biologists would like to reduce the complex communication patterns traced by molecules that regulate the health of the cell to a set of signaling rules.
However, ants have evolved a complex set of signals that allow colony members to distinguish between residents and intruders.
In disaster scenarios, the use of radar signals can be particularly complex.
To unravel the complex journey of the body's GPCRs, scientists used biophysical tools, including fluorescent biosensors; biochemical tools, such as cell signaling in neuronal cultures; as well as computational models.
«All too often, in fact, data from the brain are analysed using linear methods, but the brain is a complex system that produce signals that are non-linear and dynamic in nature and analysing with these linear methods results in loss of information.»
Dysfunction in dopamine signaling profoundly changes the activity level of about 2,000 genes in the brain's prefrontal cortex and may be an underlying cause of certain complex neuropsychiatric disorders, such as schizophrenia, according to UC Irvine scientists.
«This is the first time that this specific protein - protein signaling complex has been identified in GBM, and it gives us a new potential target for drug development,» says Fisher, Thelma Newmeyer Corman Endowed Chair in Cancer Research and co-leader of the Cancer Molecular Genetics research program at VCU Massey, professor and chair of the Department of Human and Molecular Genetics at the VCU School of Medicine, and director of the VIMM.
Frey and his colleagues made use of mathematical models to analyze the complex interplay between ecological factors and population dynamics, and were able to demonstrate that populations can indeed respond in a coordinated fashion to chemical information even when the signal molecules are generated by only a subset of the cells.
They're what gives the device its ability to decode the complex «language» of the brain, expressed through the electrical signals of large groups of neurons.
University of California, Santa Barbara, PhD student Emily Ellis and her colleagues in the laboratory of Dr. Todd Oakley are interested in the evolution of complex traits, particularly those related to vision and visual signaling.
Because traditional rigid implanted probes are invariably unstable, he explained, researchers and clinicians rely on decoding what they call the «population average» — essentially taking a host of neural signals and applying complex computational tools to determine what they mean.
Just a day after fertilization, embryonic brains begin sending signals to far - off places in the body, helping oversee the layout of complex patterns of muscles and nerve fibers.
To unravel the complex signaling pathway map, the scientists used their own findings from the analysis of factors regulated up or down in the interplay between tissue and stem cells, linking them with the signaling pathways described in existing literature.
The NIST synapse's combination of small size, superfast spiking signals, low energy needs and 3 - D stacking capability could provide the means for a far more complex neuromorphic system than has been demonstrated with other technologies, according to the paper.
The first signs of life on another planet may not be a complex signal captured by an antenna or images of a scampering creature on the horizon, but a track left in long - dried mud.
Dr. Yaffe's research focuses on the biology of the complex signaling pathways that cells use to respond to DNA damage and inflammation, particularly the role of protein kinases and modular binding domains in tumor development and anti-cancer therapeutics.
Achieving the goal of improved wireless performance is particularly challenging indoors because of the complex interactions of radio signals with the environment.
Other advances that gave the researchers a clearer view of the signaling mechanisms reported in Science include CRISPR gene editing, live - cell imaging techniques, and more powerful ways to look at all components of a protein complex.
Using radio telescopes in Spain, France, and Australia, a team headed by researchers from the Max Planck Institute for Radio Astronomy in Bonn, Germany, scanned the LMH for signals in the precise wavelengths that would reveal the presence of more complex molecules.
The researchers identified dysfunctional brain mechanisms of sustained attention using functional Magnetic Resonance Imaging data and complex modeling of fMRI signals.
At a minimum, the result is an incredibly complex web of cellular signals that are constantly working together (or in opposition, as the case may be) to adjust the number and type of proteins expressed in a cell and so, ultimately, the health of the cell itself.
«These observations unmask the relevance of primitive brain regions previously linked to eating to other complex behaviors,» said lead author Marcelo Dietrich, M.D., assistant professor of comparative medicine and neurobiology and a member of the Yale Program in Integrative Cell Signaling and Neurobiology of Metabolism at Yale School of Medicine.
But whether all the signaling is part of a complex mating system or some other form of behavior entirely remains to be seen, he added.
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