Sentences with phrase «of signaling networks»

Our approaches include gene discovery, mapping of signaling networks in cell culture models and in vivo functional analyses done through gene knock - out and knock - in techniques in mice.

Stuart explained that the integrated datasets from multiple analyses enabled the researchers to build a generic model of the signaling networks involved in metastatic prostate cancer.

Researchers are also developing rudimentary models of signaling networks in cells and simple brain circuits.

To this end Dr. Linding is currently leading high - level, strategic, multidisciplinary studies of signaling network dynamics driving cancer metastasis in collaboration with other labs at Harvard, Yale, The Jackson Laboratory, Memorial Sloan Kettering Cancer Center, MIT, and BRIC.

Additionally, ERK1 / 2 and AKT are known to cross talk with multiple substrates including several kinases, transcription factors, etc. which increase the complexity of the signaling network.

We hope to provide a more complete picture of the signalling network and to help find compounds beneficial in unravelling basic principles in signal transduction and, ultimately, in ion and enzyme secretion relevant to CF patients or in insulin secretion of s - cells.

Not exact matches

The loss of Starz hit Netflix's share price hard, since investors were concerned not just about losing access to the company's library of movies and TV shows, but about whether the move signaled that distributors and traditional networks were going to start playing hardball with the streaming service.

Instead of feeding NASA's neural network cat photos, however, the researchers fed it «15,000 signals» taken from the Kepler data that scientists confirmed were from exoplanets.

SAN JOSE, Calif., May 1 - Facebook Inc will offer its first dating service, Chief Executive Mark Zuckerberg said on Tuesday, signaling the entry of the world's largest social network into a growing market that sent shares of established dating site operators tumbling.

It helps signals move faster around the neural network, and in two important areas of the brain, the frontal and temporal lobes, myelin levels increase with age, peaking on average around age 50 and in some people continuing to rise into their 60s.

Significant investments would be needed to build a network of transmitter stations to give signal coverage, or to upgrade existing ones dating back decades when radio navigation was standard.

To build nationwide 5G, they either have to kick current customers off LTE, which would take years, or use a type of spectrum (millimeter wave) that can only carry a signal 2,000 feet from a cell site — versus multiple miles for other spectrum — making it nearly impossible for either of them to create a truly nationwide 5G network quickly.

Influencers create the kinds of signals that social network algorithms reward with higher visibility.

The decline of BB is perhaps a more familiar story, but «Losing the Signal» enhances the drama with personal human stories: how the founders» genius and strengths ultimately became their downfall: the reliance on efficiency of network and battery use ignored the groundswell of desire for an always - with - me computer.

5G and small cells go hand in hand since the technical standards of the next - generation networks will support many more connection points with fast backbone connections but lower - powered radio signals.

Google X Lab, the visionary arm of the tech company, aims to deploy a network of helium balloons floating in the stratosphere, each of them beaming a strong 4G signal to non-urban, hard to reach areas.

This appointment of a long - time party loyaltist also signals that the NDP don't have a broadly developed network of fresh talent to draw from in Calgary and southern Alberta, which may explain the large number of out - of - province hires.

If the device is connected to a Wi - Fi network, Google will route calls and data to Wi - Fi to further reduce the use of more expensive cellular signals and help customers save up on data costs.

We've built an extensive SEO Network that is designed to effortlessly address important ranking signals used by search engines to determine the value and relevancy of a website.

While some moves by the networking giant seem to give the signal that it is going out of the way to endear itself to people — like Zuckerberg holding an open Q / A session for the first time, explaining why they made the Facebook messenger a standalone app, making the privacy policy shorter and simpler to understand, others make it more than obvious that they care two hoots for the people who make up the site!

At the end of the year I concluded that a group of people can not regularly gather for what they feel to be religious purposes without developing a complex network of signals and symbols and conventions — in short, a subculture — that gains its own logic and then functions in a way peculiar to that group.

Through these introductory chapters I have stressed the idiomatic nature of parish culture, its thick networking of construable signs to form a dialect of signals and symbols.

On Radio National breakfast this morning ACCC Chairman, Graeme Samuel, was asked about price signalling between banks, the ACCC's plans to review James Packer's acquisition of an interest in the Ten Network and about the ACCC's roll in the implementation of the NBN.

When those signals suggest that life is going to be hard, the network reacts by preparing for trouble: raising blood pressure, increasing the production of adrenaline, heightening vigilance.

There is no possibility of any interference with any public or private Wi - Fi networks as well, providing a completely interference - free digital signal for an uninterrupted video footage.

The short - term dependence on the proximity of a caregiver for physiological regulation, and protection is just finally being recognized scientifically as being extremely important and beneficial (see Barak et al. 2011 Should Neonates Sleep Alone, downloadable from this website) Mosko et al., 1998; McKenna et al 2007), and helps to explain why infants should avoid sleeping alone outside the sensory range by which a caregiver and infant detect each others sensory signals, cues, or stimuli, all of which facilitate and represent interactions that augment neurological connections and provide the foundation for the development of cognition and intellectual development, and the proliferation of neural networks that support these systems.

But railway historian Christian Wolmar told TP Weekly News: «This announcement does not signal the break - up of Network Rail as some have suggested.

«In the next 15 years Network Rail has to renew 63 % of the signalling system in this country as it will be life expired,» he said.

The MTA needs to invest the lion's share of its resources in upgrading a signaling network that predates World War II — and our gutless political class needs to hold the MTA to account.

London has already installed a computerized signal network on four of its 10 main subway lines, with work is underway on four more.

The Success Academy charter school network has refused to sign mandatory contracts granting the city Department of Education oversight over its pre-kindergarten program, deputy mayor Richard Buery said Thursday, signaling the latest showdown between the charter network and Mayor Bill de Blasio's administration.

When a smartphone user walks near one of those access points, the receivers recognize their mobile devices and relay a signal to the phones, which in turn transmit the data via cellular networks or Wi - Fi to the place where they are analyzed.

By studying these examples, the neural network learned on its own what the light signal of an exoplanet looked like, and could then pick out the signatures of exoplanets in previously unseen signals.

The algorithm uses the time a signal arrives at a number of nodes, together with a map of the network's structure, to deduce the most likely source node.

So if two nodes on either side of a network see a signal at roughly the same time, the source must lie in the middle of the network; if one node sees it earlier, the source is likely to one side.

Nevertheless, on Nov. 11, 2014, a global network of robotic telescopes named ASASSN (All Sky Automated Survey for SuperNovae) picked up signals of a possible tidal disruption flare from a galaxy 300 million light years away.

All of these networks respond to a signal and produce a hormonally active substance.

So the researchers looked for a stronger signal, the wave of time shifts that would sweep across the whole 50,000 - kilometer - wide GPS network if Earth passed through a large domain wall as the galaxy rotates in its cloud of dark matter.

Rubin - Delanchy — in collaboration with Nick Heard, reader in statistics at Imperial College London, and Carey Priebe, professor of statistics at The Johns Hopkins University — has developed a «linear algebraic» approach to network anomaly detection, in which nodes are embedded in a finite dimensional latent space, where common statistical, signal - processing and machine - learning methodologies are then available.

«Our findings provide a possible flanking strategy to counteract the ability of melanoma cells to re-wire their signaling networks,» said co-coresponding author Meenhard Herlyn, Caspar Wistar Professor in Melanoma Research and director of the Melanoma Research Center at The Wistar Institute.

The major innovation, the authors say, is to combine the network analysis with the subtle statistical analyses of the early warning signals for the monsoon onset and withdrawal.

During three flybys of Enceladus, between April 2010 and May 2012, the scientists collected extremely precise measurements of Cassini's trajectory by tracking the spacecraft's microwave carrier signal with NASA's Deep Space Network.

Professor Taylor, who co-ordinated the research, says: «Our findings provide the very first insight into how biochar stimulates plant growth — we now know that cell expansion is stimulated in roots and leaves alike and this appears to be the consequence of a complex signalling network that is focussed around two plant growth hormones.

Seeking additional insight into similar mechanisms at work in other centers of the brain, Donato and his team discovered that the signal to develop one area known to be involved in more abstract functions, including memory and navigation, originated from deep within the brain, in a specific population of neurons that kicks off the maturation of an entire neural network.

Of all the human senses, the visual system — the network that turns light into neural signals that create the perception of sight — is the most studied and best understooOf all the human senses, the visual system — the network that turns light into neural signals that create the perception of sight — is the most studied and best understooof sight — is the most studied and best understood.

For this year's solar eclipse, they will observe radio signals using an existing network of GPS receivers in Missouri, and intersperse it with small, cheap GPS receivers that are similar to the kind in most phones.

A study published in the journal PLOS ONE reports that the synthetic molecule JK - 31 blocks the signalling of a «growth factor» chemical that promotes the creation of networks of blood vessels to feed tumors.

Researchers still don't know how this range corresponds to their versatile functions, but being more like a string than like a lump with keyholes means that a protein can make many contacts with other molecules to regulate the network of signals that drives the cell.

So instead of bouncing radar signals off aircraft, ADS - B uses GPS signals to continuously broadcast a plane's identity, ground position, altitude and velocity to networks of ground stations and other nearby aircraft.

The strength of the signal, direction, name and security level on these are translated into an audio stream made up of a foreground and background layer: distant signals click and pop like hits on a Geiger counter, while the strongest bleat their network ID in a looped melody.