In view
of the significant adverse impacts, SO2 emissions in the scenarios are increasingly controlled outside countries of the OECD.
A 2012 paper by the Institute for Social and Economic Research at the University of Essex studied the minimum wage and «found almost no evidence
of significant adverse impacts on employment».
Not exact matches
Examples
of these risks, uncertainties and other factors include, but are not limited to the
impact of:
adverse general economic and related factors, such as fluctuating or increasing levels
of unemployment, underemployment and the volatility
of fuel prices, declines in the securities and real estate markets, and perceptions
of these conditions that decrease the level
of disposable income
of consumers or consumer confidence;
adverse events
impacting the security
of travel, such as terrorist acts, armed conflict and threats thereof, acts
of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread
of epidemics and viral outbreaks;
adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment
of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount
of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the
significant portion
of our assets pledged as collateral under our existing debt agreements and the ability
of our creditors to accelerate the repayment
of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss
of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price
of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times
of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability
of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.
We believe that trauma - informed schools are the best educational environment for all children, but especially the
significant population
of children
impacted by
Adverse Childhood Experiences (ACEs).
«The loss
of significant offshore oil and gas tax revenues as the North Sea runs down will have a big
impact on our economy, jobs and balance
of payments, with
significant increases in household energy bills — and a very
adverse impact on the legacy for future generations in an independent Scotland,» he told EnergyVoice.com.
The Department
of Environmental Conservation and the Thruway Authority announced its finding Wednesday, saying the Pilgrim Pipeline project has the potential for
significant adverse impact on the environment and communities.
Regarding the Solar Farm proposal currently before the Town Board, solar energy is always good, but a large facility has to be reviewed so as to ensure that the
adverse impacts, such as the potential
impacts on aesthetics and the natural character
of the surrounding area, are either avoided or minimized to the point that they are not
significant.
«If you look at the timing
of that bill, as well as the content, back in late spring and early June... there was grave concern that this would have a
significant adverse impact on teachers, and that obviously didn't happen.
Quoting acting DEC deputy commissioner Thomas Berkman's reference to the project's «potential for
significant adverse environmental
impacts,» the document states, «the very large number
of affected communities demands a scoping process that can accommodate their effective participation to identify issues
of local and regional concern.»
«Because
of the close proximity
of the 137 - unit Ezra Prentice Homes residential housing development to Global's facility, the potential for these proposed changes to have
significant adverse impacts on the environment must be fully analyzed,» D.E.C. officials wrote in a letter.
A preliminary review
of the application indicates there is the potential for
significant adverse environmental
impacts associated with the construction and operation
of the pipeline, including, but not limited to,
impacts to hundreds
of acres
of forest, regulated water bodies and wetlands.»
The Planning Board conducted a review
of the project and on September 10 issued a «negative declaration» under State Environmental Quality Review Act (SEQRA) review, meaning that the Planning Board found that there would be no
significant adverse environmental
impacts from the project, and issued a «preliminary» site plan approval
of the project subject to Zoning Board
of Appeals (ZBA) review
of «performance standards.»
Trans fats — on their way to being largely phased out
of food — had the most
significant adverse impact on health.
Moreover, given the amount
of CEA - backed debt outstanding, such a failure would likely have a
significant adverse impact on the State's borrowing rate.
In addition, to the extent the Fund has
significant holdings in a particular regulated industry, regulatory changes affecting that industry may have an
adverse impact on the prices
of securities
of companies in that industry, thereby adversely affecting the net asset value
of the Fund.
A material defect is a specific issue with a system or component
of a residential property that may have a
significant,
adverse impact on the value
of the property, or that poses an unreasonable risk to people.
On the other hand, those many influences listed can also have an
adverse effect on your principal and even the smallest bit
of unrest somewhere in the world can have a
significant impact on your investment.
The therapeutic dotential
of dietary precursor modulation by a fish - oil - supplemented diet (n - 3 fatty acids), such as eicosapentaenoic acid (C20: 5,n - 3) and docosahexaenoic acid (C22: 6,n - 3) in the therapy
of ulcerative colitis has been shown to result in a 35 % to 50 % decrease in neutrophil production
of LTB4.28
Significant improvement in symptoms and histologic appearance of the rectal mucosa has been observed in several small series of patients with Crohn's disease and ulcerative colitis given fish oil at 3 to 4 g daily for 2 to 6 months in uncontrolled studies.29 However, a larger, randomized, double - blind trial comprising 96 patients with ulcerative colitis failed to reveal any benefit in remission maintenance or treatment of relapse on 4.5 g of eicosapentaenoic acid daily, despite a significant reduction in LTB4 synthesis by blood peripheral polymorphonuclear cells.30 It should be emphasized, however, that the anti-inflammatory actions of the fish oils, in addition to inhibition of LTB4, include suppression of IL - 1 and platelet activating factor synthesis and scavenging of free oxygen radicals.30 The impact of increased lipid peroxidation after fish oil supplementation should be considered when altering the n - 6: n - 3 fatty acid ratio.31 Antioxidant supplementation may be able to counteract the potentially adverse effects of n - 3 f
Significant improvement in symptoms and histologic appearance
of the rectal mucosa has been observed in several small series
of patients with Crohn's disease and ulcerative colitis given fish oil at 3 to 4 g daily for 2 to 6 months in uncontrolled studies.29 However, a larger, randomized, double - blind trial comprising 96 patients with ulcerative colitis failed to reveal any benefit in remission maintenance or treatment
of relapse on 4.5 g
of eicosapentaenoic acid daily, despite a
significant reduction in LTB4 synthesis by blood peripheral polymorphonuclear cells.30 It should be emphasized, however, that the anti-inflammatory actions of the fish oils, in addition to inhibition of LTB4, include suppression of IL - 1 and platelet activating factor synthesis and scavenging of free oxygen radicals.30 The impact of increased lipid peroxidation after fish oil supplementation should be considered when altering the n - 6: n - 3 fatty acid ratio.31 Antioxidant supplementation may be able to counteract the potentially adverse effects of n - 3 f
significant reduction in LTB4 synthesis by blood peripheral polymorphonuclear cells.30 It should be emphasized, however, that the anti-inflammatory actions
of the fish oils, in addition to inhibition
of LTB4, include suppression
of IL - 1 and platelet activating factor synthesis and scavenging
of free oxygen radicals.30 The
impact of increased lipid peroxidation after fish oil supplementation should be considered when altering the n - 6: n - 3 fatty acid ratio.31 Antioxidant supplementation may be able to counteract the potentially
adverse effects
of n - 3 fatty acids.
The Injunction The original complaint — filed by the Urban Wildlands Group, Endangered Habitats League, Los Angeles Audubon Society, Palos Verdes / South Bay Audubon Society, Santa Monica Bay Audubon Society, and the American Bird Conservancy — was brought under the California Environmental Quality Act, with the plaintiffs arguing, for instance, that TNR «can cause
significant adverse environmental
impacts by causing proliferation
of rats and raccoons and creating water pollution problems.»
In this instance, however, the overall weight
of the evidence from the cumulative body
of information contained in this Public Health Review demonstrates that there are
significant uncertainties about the kinds
of adverse health outcomes that may be associated with HVHF, the likelihood
of the occurrence
of adverse health outcomes, and the effectiveness
of some
of the mitigation measures in reducing or preventing environmental
impacts which could adversely affect public health.
That hope came to fruition Wednesday with passage
of House Bill 3561, which «prohibits construction or operation
of a wind energy facility, or facility expansion, from encroaching upon or having a
significant adverse impact on the mission, training or operations
of any military installation or branch.»
His argument will be based on probability and
impact — that there is now enough evidence to render
significant adverse impact likely, and that the human and economic cost
of inaction would outweigh the cost
of effective action.
The report found the terminal could have «
significant and
adverse»
impact on the climate, and the combustion
of coal from the terminal could generate annually as much carbon pollution as 672,000 cars.
Recalling the concern reflected in the outcome document
of the United Nations Conference on Sustainable Development, entitled «The future we want», 1 that the health
of oceans and marine biodiversity are negatively affected by marine pollution, including marine debris, especially plastic, persistent organic pollutants, heavy metals and nitrogen - based compounds, from numerous marine and land - based sources, and the commitment to take action to significantly reduce the incidence and
impacts of such pollution on marine ecosystems, Noting the international action being taken to promote the sound management
of chemicals throughout their life cycle and waste in ways that lead to the prevention and minimization
of significant adverse effects on human health and the environment, Recalling the Manila Declaration on Furthering the Implementation
of the Global Programme
of Action for the Protection
of the Marine Environment from Land - based Activities adopted by the Third Intergovernmental Review Meeting on the Implementation
of the Global Programme
of Action for the Protection
of the Marine Environment from Land - based Activities, which highlighted the relevance
of the Honolulu Strategy and the Honolulu Commitment and recommended the establishment
of a global partnership on marine litter, Taking note
of the decisions adopted by the eleventh Conference
of the Parties to the Convention on Biological Diversity on addressing the
impacts of marine debris on marine and coastal biodiversity, Recalling that the General Assembly declared 2014 the International Year
of Small Island Developing States and that such States have identified waste management among their priorities for action, Noting with concern the serious
impact which marine litter, including plastics stemming from land and sea - based sources, can have on the marine environment, marine ecosystem services, marine natural resources, fisheries, tourism and the economy, as well as the potential risks to human health; 1.
Even so, the report said that since the buildup
of the DART network it has «experienced
significant outages that can have
adverse impacts on the capability
of the Tsunami Warning Centers to issue efficient warnings, to use near real - time forecasts, and to cancel warnings.»
In this context, for the Administration to have released a U.S. Climate Action Report with a chapter on climate change
impacts that identified a range
of likely
adverse consequences, based on scientific reports including the National Assessment, could rightly be seen as an anomaly and appeared to be seen as a
significant political error by Administration allies dedicated to denying the reality
of human - induced global warming as a
significant problem.
Local and regional
impacts of climate change, both
adverse and beneficial, may indeed have
significant ramifications in other parts
of the world.
Cites conditions under which the Administrator may waive requirements for the renewable fuel program, based in part upon an assessment by the Secretary
of Energy whether the renewable fuel requirement will likely result in
significant adverse impacts on consumers on a national, regional, or state basis in 2006.
I believe the strong role
of anthropogenic contributions to climate change with potentially
significant adverse impacts (global warming and ocean acidification) is well documented by a large array
of independent evidence.
EPA's authority to review applications for consistency with the law comes from Section 404 (c) which authorizes and compels EPA to determine whether permitted activities would result in «
significant and unacceptable
adverse impacts on municipal water supplies, and prohibit, restrict, or deny, including withdrawal, the use
of any defined area as a disposal site.»
CO2 limits will hurt the poor «Legally mandated measures for reducing greenhouse gas emissions are likely to have
significant adverse impacts on GDP growth
of developing countries, including India.»
«The most
significant labor case on this year's Supreme Court docket was handed down this morning, with a somewhat muddled result,» writes employer's lawyer Mike Fox in his assessment
of the Supreme Court's reversal
of the 5th Circuit's decision, rejecting the theory
of adverse impact under the Age Discrimination Act.
The current economic recession has had a
significant adverse impact on clients, including the financial services, real estate, high tech sectors, that are the foundation
of revenue for many law firms.
Additionally, the
impact of the costs
of extended medical care in treating such injuries combined with the trauma that goes along with such ordeals can have a
significant and
adverse impact on a person.
The second session
of the International Conference on Chemicals Management (Geneva, 10 - 15 May 2009) will review progress made toward achieving the Johannesburg Plan
of Implementation goal that by 2020 chemicals will be produced and used in ways that minimize
significant adverse impacts on the environment and human health.
Therefore, federal assessment
of impacts in these areas with a view to preventing
significant adverse effects is likely intra vires, even when there is no decision to be made under other Federal statutes.
We believe that trauma - informed schools are the best educational environment for all children, but especially the
significant population
of children
impacted by
Adverse Childhood Experiences (ACEs).
These results are similar to those found in other sustained nurse home visiting studies, 1 14 although the intervention
impacted on a broader range
of domains
of the home environment for this subgroup
of women than has been reported previously.1 An increasing body
of evidence from both animal and human studies suggests that stress in pregnancy has
significant impacts on developmental and behavioural outcomes for children.29 While the mental development
of children
of mothers who were not distressed antenatally in both the intervention and comparison groups was comparable with the general population, children's development was particularly poor in the distressed subgroup in the absence
of the MECSH intervention, suggesting that sustained nurse home visiting may be particularly effective in ameliorating some
adverse developmental
impacts for children
of mothers with antenatal distress.
Our adult ADHD case definition also required endorsement
of the M.I.N.I. statement that ADHD symptoms were having a
significant adverse impact in 2 or more settings.
PND is now recognized, by virtue
of the distress caused to mothers, as well as the wider
adverse impact on the family, as a
significant public health issue.
Furthermore, both the United States
of America and New Zealand had made
significant attempts to convert Indigenous customary land to individual freehold title and leasehold title, and recently both countries have taken steps to overturn this approach due to
adverse impacts.
A material defect is a specific issue with a system or component
of a residential property that may have a
significant,
adverse impact on the value
of the property, or that poses an unreasonable risk to people.