Sentences with phrase «of simian immunodeficiency»

The first reports that gene - editing of bone marrow stem cells in monkeys infected with a variant of simian immunodeficiency virus (SIV) significantly reduces the number Read more about Gene - editing and vaccines could improve HIV treatment - Scimex

The first reports that gene - editing of bone marrow stem cells in monkeys infected with a variant of simian immunodeficiency virus (SIV) significantly reduces the number of dormant «viral reservoirs» that pose a risk of reactivation.

In April two studies of simian immunodeficiency virus, a kin of HIV that infects monkeys, reported that the virus swiftly infects and decimates key immune cells in the gut within days, not years, of infection.

Researchers believe that sometime in the 1930s a form of simian immunodeficiency virus (SIV) jumped to humans who butchered or ate chimpanzee bush meat in the Democratic Republic of Congo.

So far only one person, a 62 - year - old Cameroonian woman living in Paris, France, has been found to be infected with the virus, which closely resembles strains of simian immunodeficiency virus (SIV) recently discovered in wild western gorillas.

Not exact matches

To study the pathogenesis of HIV - induced PNS disease, Jamie Dorsey, Research Technologist, and the research team led by Dr. Mankowski developed a simian immunodeficiency virus (SIV)- infected macaque model that closely reflects key peripheral nervous system (PNS) alterations seen in HIV patients with peripheral neuropathy.

Their hypothesis draws on the observation that sooty mangabeys (monkeys) infected with the simian immunodeficiency virus (SIV)-- a pathogen thought to be the ancestor of HIV — have a high viral load but low immune activation.

Taking a cue from AIDS researchers, who use simian immunodeficiency virus in monkeys as a model for HIV infection, Fred Wang of Brigham and Women's Hospital and Harvard Medical School in Boston set out to find a primate version of EBV.

Vaccine - mediated protection of nonhuman primates against low doses of cell - free HIV - 1, HIV - 2, or simian immunodeficiency virus (SIV) has been demonstrated.

And in a study of monkeys, researchers discovered that a cytomegalovirus - based vaccine protected 50 percent of animals from infection by simian immunodeficiency virus.

HIV's close cousin, the simian immunodeficiency virus (SIV), has been around for tens of thousands of years — much longer than the few hundred years that some studies had suggested.

The ebola virus is responsible for thousands of gorilla and chimpanzee deaths in Africa and the origin of HIV, the virus which causes AIDs, is SIV, simian immunodeficiency virus.

Studying simian immunodeficiency virus (SIV), the team found that specialized cells in the intestine called Paneth cells are early responders to viral invasion and are the source of gut inflammation by producing a cytokine called interleukin - 1 beta (IL - 1β).

Now a research team led by investigators at Beth Israel Deaconess Medical Center (BIDMC) in collaboration with the U.S. Military HIV Research Program has demonstrated that the viral reservoir is established strikingly early after intrarectal simian immunodeficiency virus (SIV) infection of rhesus monkeys and before detectable viremia.

One, the simian immunodeficiency virus, is the predecessor of HIV; the other is simian T - lymphotropic virus 1, whose descendant in humans, HTLV - 1, can cause leukemia.

Given that adipose tissue (which makes up between 15 and 20 % of the body weight in healthy people) is a source of inflammation in obese individuals, Christine Bourgeois and Olivier Lambotte, from the University Paris SUD, France, and colleagues, decided to investigate a possible role of the adipose tissue in humans infected with HIV and in macaques infected with simian immunodeficiency virus (SIV, an HIV relative that causes AIDS - like disease in some non-human primates).

The sooty mangabey, found in West Africa, has somehow adapted to the simian immunodeficiency virus — the nonhuman version of HIV — so that even with a high viral load, it rarely gets sick.

A new study led by scientists at Beth Israel Deaconess Medical Center (BIDMC) shows that an HIV - 1 vaccine regimen, involving a viral vector boosted with a purified envelope protein, provided complete protection in half of the vaccinated non-human primates (NHPs) against a series of six repeated challenges with simian immunodeficiency virus (SIV), a virus similar to HIV that infects NHPs.

The virus most closely related to HIV - 1 is a simian immunodeficiency virus (SIV) thus far identified only in captive members of the chimpanzee subspecies Pan troglodytes troglodytes.

A new study, published in PLOS Pathogens, investigates the genome editing of bone - morrow stem cells in pigtail macaques as a potential treatment for simian / human immunodeficiency virus (SHIV).

The tale of the «cut hunter» is just a theory, but it's considered one of the most plausible scenarios for how a simian immunodeficiency virus jumped from chimps to humans and became HIV.

Because of HIV's close resemblance to a simian immunodeficiency virus, researchers knew it must have originated as a virus carried by chimps.

SIV -(simian immunodeficiency virus): an HIV - like virus that infects and causes an AIDS - like disease in some species of monkeys.

Guido Silvestri, MD, division chief of Microbiology and Immunology at the Yerkes Research Center at Emory, and several of his research colleagues performed the first hematopoietic stem cell transplantation in three rhesus macaques infected with a simian human immunodeficiency virus (SHIV).

Reporting in Nature Medicine this week, Philip Johnson, a professor of pediatrics at the University of Pennsylvania, in Philadelphia, and his colleagues managed to protect monkeys from infection with the simian immunodeficiency virus (SIV), the animal model that is closest to HIV, by shuttling a gene into their muscles that produces antibody - like molecules that work against SIV.

Superior efficacy of a human immunodeficiency virus vaccine combined with antiretroviral prevention in simian - human immunodeficiency virus - challenged nonhuman primates.

Magnitude and quality of cytokine and chemokine storm during acute infection distinguish non-pathogenic and pathogenic simian immunodeficiency virus infections of nonhuman primates.

The research showed evidence that in rhesus macaques infected with simian immunodeficiency virus (SIV), the monkey form of HIV, loss of IL - 17 producing CD4 + and CD8 + T cells was associated with damage to the colon epithelium and with immune activation (see Monkey Matters, IAVI Report, Nov. - Dec.

School of Veterinary Medicine researchers first described simian and feline immunodeficiency viruses in monkeys and cats, which became the earliest animal models for AIDS research.