Sentences with phrase «of spatial learning»

An object and place association - dissociation - association binding model (ADA) of spatial learning integrates object - based (object permanence) with space - based accounts of the A-not-B task

An object and place association - dissociation - association binding model (ADA) of spatial learning integrates object - based (object permanence) with space - based accounts of the A-not-B task Show more

Mu, J.S., et al. «Deprivation of Endogenous Brain - Derived Neurotrophic Factor Results in Impairment of Spatial Learning and Memory in Adult Rats,» Brain Research 835 (1999): 259 - 265

That means I need to find ways to increase BDNF more than in someone with the normal gene in order to preserve my cognitive function, memory, and emotional regulation.8 Mu, J.S., et al. «Deprivation of Endogenous Brain - Derived Neurotrophic Factor Results in Impairment of Spatial Learning and Memory in Adult... continue 9Cirulli, F., et al. «Intrahippocampal Administration of BDNF in Adult Rats Affects Short - term Behavioral Plasticity in the Morris Water Maze and... continue

Changes in the time it takes the rodent to find the platform in a series of successive trials can be used as a measure of spatial learning and memory.

In a test of spatial learning and memory, the mice with extra klotho performed twice as well.

Direct hippocampal stimulation in six subjects had no effect on their performance of the spatial learning tasks, as compared with no stimulation, with respect to both latency (z = 0.52, P = 0.69)(Figure 2B) and excess path length (z = − 0.52, P = 0.69)(Figure 2D).

Here, we examined the extent to which performance in the Morris water maze — the most frequently used behavioral assay of spatial learning and memory in rodents — translates to humans.

There was no difference between mutant and normal mice when it came to investigating an empty cage, however, and the mutants even outperformed normal mice on a test of spatial learning and memory, suggesting that their deficit was specific for social behavior.

Not exact matches

- strengthening the upper body and core muscles for other gross motor tasks - strengthening the upper body and core muscles to create a stable base for fine motor skills - developing stability in the bones of the shoulder joint (the ball and socket joints of the shoulders and hips are shallow and unstable at birth but are molded into stronger, more stable joints through weight - bearing)- visual development to quickly shift focus from near to far - hand - eye - coordination - providing plentiful early opportunities for motor planning (movement problem - solving)- refining balance - integrating the movement (vestibular), pressure & stretch (proprioceptive), visual and touch (tactile) sensory systems - learning to coordinate movements where two sides of the body are doing different movements - learning to coordinate upper body and lower body movements - developing body awareness and spatial awareness - fostering independence

Luckily, parents of girls can encourage a more mathematical mindset by offering spatial toys like blocks, balls, and technology aids that encourage learning engineering and tech concepts.

Your baby is now learning to hone the skill of throwing and even has a spatial awareness which allows them to throw a ball with a certain amount of accuracy.

Two new studies show how spatial parts of the brain are already functioning in infancy, revealing that not everything we understand about our surroundings is learned

Mice bred to have autismlike symptoms were injected with low doses of antianxiety drugs and showed notable behavioral shifts: improved social interaction, decreased repetitive behaviors and better spatial learning.

As part of the limbic system, it plays an important role in memory processing and spatial cognition, including how mammals learn to understand and navigate their environment.

Previous studies focusing on spatial - reward associative learning in foraging animals have assumed that foraging efficiency increases as the forager learns the locations of greater rewards.

According to McQuillan, a Ph.D. candidate in evolutionary biology at Lehigh and lead author of the study, the northern Black - capped Chickadee is a model species for studying spatial memory and learning, traits that are key to scatter - hoarders» survival.

The data have helped them learn more about the snakes» spatial range and behavior and develop population models they hope will be useful for conserving the locally threatened population of pine snakes.

«The pattern of activity in a brain region involved in spatial learning in the virtual world is completely different than when it processes activity in the real world,» said Mayank Mehta, a UCLA professor of physics, neurology and neurobiology in the UCLA College and the study's senior author.

For example, EEGs indicate that sleeping rats replay the running of a maze in a brain region devoted to spatial learning.

«By refining the spatial pattern of mass loss in the world's second largest — and most unstable — ice sheet, and learning how that pattern has evolved, we are steadily increasing our understanding of ice loss processes, which will lead to better - informed projections of sea level rise.»

That is changing, says Nora Newcombe, a professor of psychology at Temple University and principal investigator of the Spatial Intelligence and Learning Center.

«My lab works on the neural bases of learning and memory,» says Pozzo - Miller, «so we decided to test if LM22A - 4 was able to improve spatial discrimination deficits by enhancing synaptic plasticity in the hippocampus, the brain region responsible for spatial learning and memory.»

In a 2014 study in rats, researchers at the University of California found that the neurons in a brain region associated with spatial learning behaved completely differently in virtual environments compared to in real ones, with more than half of the neurons shutting down while in VR.

Co-author Dr Lisa Leaver of the University of Exeter added: «We predicted that squirrels would be quick to learn this task because learning spatial arrays is crucial for them in order to recover their food caches in the winter months.

«They drive all sorts of different forms of learning, the simplest being what we found here: spatial learning, contextual learning.»

In the future, the researchers are interested in examining how the neural substrates of social and spatial learning differ in mouse models of autism.

Witten and her research team performed optogenetic experiments with the mice to isolate precisely which circuits of the brain are involved in social - spatial learning.

«Using this combined approach, we were able to reduce the levels of amyloid - beta, but, importantly, restored spatial learning and memory to the level observed in healthy mice,» Jankowsky said.

These developmental defects in the wiring of neural circuits cause very selective alterations in spatial learning and memory in adult mice.

Common complications include high blood pressure, curvature of the spine, and specific learning problems, which are often related to spatial cognition.

Stimulation of the entorhinal region enhanced memory of spatial information when applied during learning.

A deficit in procedural learning can alter performance in the hidden - target task and confound the interpretation of spatial memory.

Our results show that spatial learning in humans can be enhanced by electrical stimulation of the entorhinal region, a specific site within the medial temporal lobe and the chief gateway into the hippocampus.

The subjects completed a spatial learning task that consisted of navigation through a virtual environment to deliver passengers to stores (Fig. 1 in the Supplementary Appendix).

Analysis of the distance, latency, and cumulative search error (CSE) rank - summary scores revealed that MCI - AD patients and hAPP mice were significantly impaired in this task (Table 1 and Figure 1, B — D and F — I), consistent with a deficit in hippocampus - dependent spatial learning.

The graphs show the behavioral performance of six subjects on spatial learning tasks during stimulation and nonstimulation of the entorhinal region (Panels A and C) and the hippocampus (Panels B and D).

Figure 2 shows the average of the subjects» behavioral performance during spatial learning with unilateral stimulation of the entorhinal region or hippocampus.

Although the behavior of the mutant mice seemed mostly normal, further testing showed that they had deficiencies in spatial learning, confirming the enzyme's key role in that process.

Harding, a medicinal chemist, and Wright, a neuroscientist, have been working on their compound since 1992, when they started looking at the impact of the peptide angiotensin IV on the hippocampus, a brain region involved in spatial learning and short - term memory.

In the AD reversal treatment strategy described here, J147 significantly improved several different aspects of memory affected in AD, including spatial memory, a disinhibition phenotype and hippocampal dependent associative learning (Figure 1).

They have spatial learning and memory defects as assessed in the Morris water maze and the radial arm maze, show developmental delay in sensorimotor milestones, and exhibit locomotor hyperactivity, lack of behavioral inhibition, and stereotypic behavior.

A large body of evidence indicates that theta rhythm is likely involved in spatial learning and navigation (Buzsáki, 2005).

Spatial learning ability of the threespine stickleback (Gasterosteus aculeatus) in relation to inferred ecology and ancestry.

The dentate gyrus, part of the hippocampus, is involved in learning, episodic memory formation and spatial coding.

Both assessments test spatial learning and require proper activation of the hippocampus, a brain structure that is one of the regions affected earliest in Alzheimer's disease.

The idea that the activity of a place cell is predictive and can be modified by learning and the behavior of other animals may make it easier to conceptualize an all - encompassing framework that ties together the hippocampus» role in spatial navigation with its well - established role in learning and memory formation.

Discovered that the persistent sodium current, INaP, paradoxically amplifies afterhyperpolarizations and reduces the frequency (f / I) gain, and strongly modulates spike timing (Vervaeke et al., Neuron 2006); that Kv7 / M / KCNQ - type K + channels but not SK channels are essential for excitability control in hippocampal neurons (Gu et al., J Physiol, 2005); that Kv7 / M / KCNQ - type K + channels are essential for spatial learning and prevention of epilepsy (Nature Neuroscience 8: 51 - 60, 2005), that KCa1 / BK - type K + channels are essential for cerebellar learning and motor control (Proc Natl Acad Sci USA 101: 0474 - 8, 2004), the role of postsynaptic voltage-gated K + channels in regulation of synaptic plasticity (LTP) and integration (Proc Natl Acad Sci USA 99:10144, 2002); that Kv7 / M / KCNQ - type K + channels are essential for intrinsic theta resonance in hippocampal neurons (J Physiol 545:783, 2002).

http://onlinelibrary.wiley.com/doi/10.1002/asia.201600259/full Subcutaneous administration of cyclodextrin significantly improved spatial learning and memory deficits in Alzheimer disease mice model doi: 10.1084 / jem.20121239.

In monkeys, deficiency of male hormones impairs the development of spatial perception (which, in humans, is normally more acute in men than in women), of learning ability and of visual discrimination tasks (such as would be required for reading.)