Sentences with phrase «of stable disease»

Research from Rutgers Cancer Institute of New Jersey shows that the «first in human» series of vaccine injections given directly into a pancreatic cancer tumor is not only well tolerated, but also suggests an «encouraging» period of stable disease.

«Encouraging» period of stable disease suggested in direct injection vaccine treatment of pancreatic cancer.»

Of 22 patients evaluable for response, 3 (14 percent) had very good partial responses, 3 (14 percent) had minor responses, and 10 (45 percent) had a period of stable disease.

«We can reassert control, at least in terms of stable disease, in essentially everybody we've treated so far,» Wrangle said.

Not exact matches

Since stable, long - term monogamous relationships would solve much of the disease problem in the gay community, and we are just getting started in encouraging those, I think sheer compassion would drive Jesus to join that effort.

Caregiver duties and responsibilities can include: Assisting with personal care: bathing and grooming, dressing, toileting, and exercise Basic food preparation: preparing meals, shopping, housekeeping, laundry, and other errands General health care: overseeing medication and prescriptions usage, appointment reminders and administering medicine Mobility assistance: help with getting in and out of a wheelchair, car or shower Personal supervision: providing constant companionship and general supervision Transportation: driving to and from activities, running errands, and help getting in and out of wheelchair - accessible vehicle Emotional support: being a stable companion and supporter in all matters personal, health - related and emotional Care for the elderly: orienting or grounding someone with Alzheimer s disease or dementia, relaying information from a doctor to family members Back - up care (or respite) services: providing other caregivers a break Home organization: help with organizing

Trans fats — fats that are partially hydrogenated, making them more shelf - stable — have been linked to higher levels of bad cholesterol and elevated risk of coronary heart disease.

While the disease remains a modest threat in rural, undeveloped areas, Green warns that our current stable relationship with plague in the developed world is only as good as our control of urban rodent populations.

Eran Bendavid of Stanford University, US, discussing the research in an accompanying Perspective, says: «Averting deaths of young children from malaria or vaccine - preventable diseases such as polio or measles promotes more stable and prosperous societies.

Of these nine patients, 100 percent either had stable disease or had a partial response to the treatment used in this study.

Of the 21 patients treated, nine previously either had stable disease or responded to single - agent immunotherapy before becoming resistant to this treatment.

Populations of this unique species, currently known as highly threatened, were previously considered to have remained relatively stable in the face of the disease that has ravaged many amphibian species worldwide, but the frogs may have been infected over a decade ago, with the impacts only recently observed.

This could greatly expand the utility of hair restoration surgery to women and to younger patients — now it is largely restricted to the treatment of male - pattern baldness in patients with stable disease.»

The clear result of this clinical study — that the combination reduced strokes, heart attacks and cardiovascular death by practically 25 per cent compared to either drug alone in both patients with stable coronary or peripheral artery disease — caused the clinical trial to be stopped early, after 23 months, in February 2017.

Although aspirin reduces the risk of major cardiovascular events by 19 per cent, a more effective antithrombotic strategy could have major benefits for the large population of patients with stable cardiovascular disease.

Of the 10 patients enrolled in the study — a clinical trial designed to evaluate safety and feasibility — none of the participants experienced any dangerous side effects and one patient's disease remained stable after 18 monthOf the 10 patients enrolled in the study — a clinical trial designed to evaluate safety and feasibility — none of the participants experienced any dangerous side effects and one patient's disease remained stable after 18 monthof the participants experienced any dangerous side effects and one patient's disease remained stable after 18 months.

In melanoma, researchers observed prolonged stable disease in 20 percent of the patients on temozolomide.

In a bid to get round some of these issues the researchers looked at the association between occasional or persistent mental distress and the risk of death in 950 people with stable coronary heart disease who were between 31 and 74 years old.

Research has shown that miRNA molecules are incredibly stable in blood, making them an excellent biomarker of disease.

In cohort two, which had patients that were heavily pretreated, six patients had a partial response, and six achieved stable disease for at least six months, for a combined disease control rate of 54.5 percent.

This study of 27 patients indicates that temsirolimus, an mTOR inhibitor, and HCQ is safe and tolerable, blocks autophagy, and had significant antitumor activity; researchers observed stable disease in 75 percent of those patients with metastatic melanoma.

More people are eating gluten - free, although the prevalence of celiac disease appears to have remained stable in recent years, according to an article published online by JAMA Internal Medicine.

And they go on to say: «These findings suggest that in patients with stable [coronary heart disease], long term mortality risk is related to the cumulative burden of psychological distress.»

Further experiments revealed that modulating activity of ATP synthase with J147 changes the levels of a number of other molecules - including levels of ATP itself - and leads to healthier, more stable mitochondria throughout aging and in disease.

Persistent moderate to severe mental distress is linked to a significantly heightened risk of death among patients with stable coronary heart disease, finds research published online in the journal Heart.

An analysis of diagnostic test results from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial — in which patients with stable chest pain were randomized to either anatomic or functional testing as an initial diagnostic strategy — showed that the presence and extent of coronary artery disease detected by CT angiography better predicted the risk for future cardiac events than did measures of exercise tolerance or restricted blood flow to the heart muscle.

In previous studies, the same group along with others had demonstrated that microRNAs (miRNAs) produced by eukaryotic cells and viruses are present in human blood in highly stable, cell - free forms and these so called circulating miRNAs can serve as non-invasive biomarkers for the early diagnosis of various diseases, including viral diseases.

«Hardening, or «furring», of the arteries can lead to very serious disease, but it's not clear why the plaques are stable in some people but unstable in others,» explains Professor David Newby, the BHF John Wheatley Professor of Cardiology at the Centre for Cardiovascular Science, University of Edinburgh.

The University of Florence team's 2011 statistical analysis of health outcomes for almost 1,700 male patients showed that those involved in stable extramarital relationships had about twice the cardiovascular disease as other patients in the study, particularly if the man reported that his wife was still sexually interested in him.

The MDS stem cells were rare, sat at the top of a hierarchy of MDS cells, could sustain themselves, replenish the other MDS cells, and were the origin of all stable DNA changes and mutations that drove the progression of the disease.

While no clinical benefit could be definitively determined from the study, one patient did achieve stable disease at the 18 - month follow up, a response that remains today, following infusion of CART - EGFRvIII.

Overall, 65.2 % of patients on regorafenib showed complete or partial response or stable disease, compared to 36.1 % of the placebo group.

The disease control rate (defined as partial response or stable disease for more than 12 weeks) for all patients was 32 percent (6 of the 19 patients) and 50 percent (three of six patients) in patients who received one prior line of chemotherapy.

Of the 19 pancreatic patients, one had a complete response and two had partial responses, while four patients had stable disease.

One of these patients has stable disease and the other has a durable confirmed partial response.

The study included 22,917 patients from 19 medical centers in Ontario, Canada, who received a diagnosis of stable coronary artery disease following coronary angiogram for chest pain (chronic stable angina) between Oct. 1, 2008, and Sept. 30, 2013.

Bone diseases, either genetic (X-linked hypophosphatemia) or dietary (rickets), represent an essential failure of the bone cell secretory system to maintain a stable calcium phosphate - mineralized collagen scaffold.

Data from the trial on 29 patients presented in June of this year showed that 24 % of the patients achieved a partial response, 14 % a minimal response, and another 24 % had stable disease.

Of these patients, 1 achieved a durable complete response (95 weeks), 1 achieved a durable partial response (53 weeks), 1 had a transient partial response, and 3 had stable disease at the conclusion of the triaOf these patients, 1 achieved a durable complete response (95 weeks), 1 achieved a durable partial response (53 weeks), 1 had a transient partial response, and 3 had stable disease at the conclusion of the triaof the trial.

There were five partial responses across the six cohorts (10.4 %), and 15 patients had stable disease (31.3 %); this yielded a clinical benefit rate of 41.7 %.

When examined alone, the ASPS patients had a clinical benefit rate of 83 %, as two patients had stable disease along with the three partial responses.

Further experiments revealed that modulating activity of ATP synthase with J147 changes the levels of a number of other molecules — including levels of ATP itself — and leads to healthier, more stable mitochondria throughout aging and in disease.

Following completion of a massive epitope discovery effort (also supported by an HHS contract), current work on MTB includes development of tools to isolate MTB - specific T cells (supported by the Gates Foundation) and identifying T cell signatures that distinguish three possible infection states: cleared infection, stable latent infection, and latent infection with high risk of progression to disease (in conjunction with a large consortium led by Henry Blumberg at Emory University).

These epithelial organoid cultures are genetically and phenotypically extremely stable, allowing transplantation of the cultured offspring of a single stem cell, as well as disease modeling by growing organoids directly from diseased patient tissues (45).

Most of the patients had a long CFS disease duration, also with a stable or worsening clinical course the last year before study entry.

Within the subset of 23 patients that were in the higher dose cohorts and would qualify for the Toca 5 trial, patients had a median survival of 14.4 months and 43.5 % (10/23) of patients had clinical benefit (5 complete responses and 5 stable disease patients).

[10] Complete responses (CRs) and partial responses (PRs) were reported in 3.2 % and 8.7 % of patients, respectively, with stable disease (SD) in 25 % of the two patient cohorts combined.

Participants were divided into four groups: those diagnosed with probable Alzheimer's when entering the study, healthy controls with no sign of dementia, individuals with mild cognitive impairment that remained stable over the two to three years for which scans were available, and those with mild cognitive impairment that progressed to Alzheimer's disease during the study.

«Ebola has been around for 40 years so we have a pretty good sense of how it functions and its genome has been pretty stable,» says Dr. Tom Frieden, director of the U.S. Centers for Disease Control and Prevention (CDC).

A low glycemic index — below 55 — is considered best to maintain stable blood sugar levels, while a high glycemic index — of 70 and above — can increase your risk of suffering from obesity, diabetes and heart diseases.