DOYLESTOWN, Pa. (January 23, 2018)-- For decades, researchers have tried to target cancer therapies to only the cancerous cells, to avoid the toxic bystander effects
of standard chemo and radiation therapy to normal cells.
In a mid-stage trial, 16 of 37 lung cancer patients given a placebo ahead
of standard chemo wound up hospitalized with severely low white blood cell counts.
Not exact matches
Howard Safran, MD, Interim Division Director, Division
of Hematology / Oncology and professor
of medicine at The Warren Alpert Medical School
of Brown University, and Denise Luppe, oncology research nurse supervisor, told Christine that they'd just started a Phase 2 clinical trial with a less toxic combination
of drugs than the
standard chemo protocol.
In contrast, no difference was observed in the sensitivity
of these cell lines to cytosine arabinoside (ARA - C), a
standard chemo - therapeutic drug which targets different pathways (data not shown).
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Standard chemo with radiation actually intentionally induces formation
of free radicals which has a selective effect on tumors and normal tissue.
Meningiomas are now 34 %
of new primary brain tumors, more than GBMs and strike twice as many women as men, yet no
standard chemo exists.
Meningiomas are now 34 %
of new primary brain tumors, more than GBMs and strike twice as many women as men, yet no
standard chemo exists.