«He was always using my experimental versions,» said Jones, then at the Max Planck Institute for Biochemistry, now professor
of structural biology at Uppsala University in Sweden.
«Now it is time to start making a serious impact on the
field of structural biology of G protein - coupled receptors and other challenging membrane proteins and complexes.
Since then, she has handled research papers in the
areas of structural biology, biochemistry, and biophysics as an Associate and Senior Editor.
«At the time, there were rapidly evolving techniques and there was a need for someone who could bridge between the hardware, software and
knowledge of structural biology methods to put things together,» says Sliz, who also collaborated with Walz on solving the clathrin lattice, with Stephen Blacklow on the Notch complex and with Suzanne Walker on o - GlcNAc transferase (OGT).
Nicola G. A. Abrescia, group
leader of structural biology at the Center for Cooperative Research in Biosciences (Centro de Investigación Cooperativa en Biociencias, CIC bioGUNE), is funded by Ikerbasque.
The three studies, published in tomorrow's issue of Nature, push the
limits of structural biology and set an important precedent for understanding how molecular pumps work, including those in humans, notes Werner Kühlbrandt of the Max Planck Institute of Biophysics in Frankfurt am Main, Germany.
«This selenium phasing technique is called «the magic
bullet of structural biology» because it's very powerful,» says Mark Hunter, SLAC scientist.
«This is a complete reversal» of earlier goals, said Cyrus Chothia, a
theoretician of structural biology at the Medical Research Council Laboratory of Molecular Biology in Cambridge, U.K..
We utilize a
combination of structural biology, biochemistry, and cell biology to determine the unique and critical protein and nucleic acid components in these pathways that can be targeted for new therapeutic strategies aimed at drug resistant infections.
In Leemor Joshua - Tor's lab, researchers study the molecular basis of nucleic acid regulatory processes using the
tools of structural biology and biochemistry.
In addition to advising and at times leading committees that have managed the National Synchrotron Light Source at Brookhaven National Laboratory, she has served on advisory panels on the
future of structural biology and on the biomedical workforce for the National Institutes of Health.
«The last 50
years of structural biology has been about trying to get detailed pictures of all the parts of the cell to understand them thoroughly,» Yeates said.
The work, which combines the static snapshot - oriented
techniques of structural biology with the dynamic live imaging of single molecule fluorescence, provides a view, for the first time, of a protein cruising inside the microtubule lumen.
«Don Wiley pioneered the
use of structural biology and structural methods to provide insights into biological problems,» she says.
The rapidly changing state - of - the - art demands that young researchers are trained to meet these new experimental, technical and analysis challenges at the
forefront of structural biology and photochemistry.
After earning a chemistry degree at MIT in 1985, Julie Forman - Kay headed to Yale for graduate work in the
lab of structural biology pioneer Fred Richards.
Working at the
interface of structural biology, biochemistry and biophysics constituted fantastic training for my future forays into interdisciplinary research.
Very close cooperation between traditionally separate fields of research continues to be absolutely essential at the very cutting
edge of structural biology.
Professor Curry,
professor of structural biology at Imperial College London, announces the new signatories to the declaration in a column published in Nature on 8 February.
During this period I continued to work in the
area of structural biology but also had the freedom to develop a bioinformatics - oriented laboratory.
Many neurodegenerative diseases, such as Alzheimer's and Parkinson's, are being studied beneficially in the light of new
knowledge of structural biology and protein folding.
«We produced uromodulin using mammalian cells, both as a net that we could examine under a microscope and in a form that can be crystallised,» says principal investigator Luca Jovine, professor
of structural biology at the Department of Biosciences and Nutrition at Karolinska Institutet.
In Huntington's and several other progressive brain diseases, certain proteins aggregate to form plaques or deposits in the brain, said senior investigator Patrick C.A. van der Wel, Ph.D., assistant professor
of structural biology, Pitt School of Medicine.
«Until now, it often has been a real mystery which antigens T cells are recognizing; there are whole classes of disease where we don't have this information,» said Michael Birnbaum, a graduate student who led the research at the School of Medicine in the laboratory of K. Christopher Garcia, the study's senior author and a professor of molecular and cellular physiology and
of structural biology.
Berkeley Lab played a key role in the 2017 Nobel Prize in chemistry, awarded today, honoring the development of cryo - EM, an imaging technique that has launched the fields
of structural biology and biochemistry into an exciting new era of discovery.