The National Institute of Health, a government agency (not funded by pharmaceutical grants) conducted a clinical trial to see if desiccated thyroid therapy is advantageous to T4 alone (8) The authors of the study concluded: «DTE (Desiccated Thyroid Extract) therapy did not result in a significant improvement in quality of life; however, DTE caused modest weight loss and nearly half (48.6 %)
of the study patients expressed preference for DTE over l - T4 (Levothyroxine).
The authors also showed that children who tested positive for high - risk sepsis but survived the infection (21 percent
of study patients) had greater degrees of organ failure and longer stays in the intensive care unit.
Moreover, the demography of the Ashkenazi population, the largest isolated population in the U.S., enables large - scale recruitment
of study patients and hence more genetic discoveries than in other well - known isolated populations like the Amish and Hutterites locally, or the Icelanders overseas.
All of the study patients received biological valves, developed from animal or donated human tissue.
Meanwhile, nine
of those study patients continued to lose weight, eventually reaching 15 percent weight loss.
The team found that patients with more varied types of bacteria in their digestive tract had longer median progression - free survival, defined at the time point where half
of studied patients have their disease progress.
The analysis showed that, during the two years prior to surgery, around 22 percent
of the studied patients had at least one emergency department (ED) visit or hospitalization in each one - year period.
Cook and colleagues were able to confine their study to patients who unquestionably had the disorder, based on an unusually thorough, six - hour evaluation
of each study patient by a multi-disciplinary clinical team that specializes in ADHD.
Dr. Cook and colleagues were able to confine their study to patients who unquestionably had autism, based on an unusually thorough evaluation
of each study patient by a multi-disciplinary clinical team that specializes in this disorder.
Not exact matches
«From 2012 to 2015, the absolute number
of patients treated with nitroprusside decreased by 53 %, and the number treated with isoproterenol decreased by 35 %,» wrote the
study authors.
While the new mid-stage
study results from DNDi were impressive (they showed cure rates
of 96 % to 97 % even for the sickest
patients and those with liver scarring), more late - stage trials will be necessary before the drug is available on a large scale in the developing world.
A new
study published in the New England Journal
of Medicine finds that Valeant Pharmaceuticals» infamous price hikes for a pair
of heart drugs called nitroprusside and isoproterenol — whose prices were increased by 310 % and 720 %, respectively — had significant downstream effects on
patient care.
A two - month 2010
study of nearly 300 cancer
patients at the Mayo Clinic found that those given 1,000 or 2,000 milligrams
of ginseng each day reported feeling more energized compared with those who took a placebo.
GOOGLE»S AI HELPS TO PREDICT CARDIOVASCULAR CONDITIONS BY ANALYZING EYE SCANS: Google and Verily — Google - parent Alphabet's life sciences unit — are exploring new ways that artificial intelligence (AI) can be used to identify
patients» risk
of suffering from a cardiovascular event, such as a heart attack or stroke, according to a newly published
study by the two Alphabet subsidiaries.
In all
studies, we assigned
patients measures
of unconventional natural gas development activity.
Finally, in our
study of symptoms, we found
patients with higher unconventional natural gas development activity had higher odds
of nasal and sinus, migraine headache and fatigue symptoms compared to those with lower activity.
A series
of preliminary Mayo Clinic
studies conducted in 2010 showed promise for the potential use
of a chemical component
of green tea (epigallocatechin gallate) in reducing the number
of cancer cells in
patients with chronic lymphocytic leukemia.
In the asthma
study, we found increased odds among asthma
patients of asthma hospitalizations, emergency department visits and a medication used for mild asthma attacks with higher unconventional natural gas development activity, compared to those with lower activity.
In health care, this amounts to an hourly avalanche
of new research papers, clinical trials, scientific
studies, and
patient health information.
A small pilot
study of schizophrenia
patients found that a particular video game where the user has to land a rocket helped the
patients control verbal hallucinations.
The
study participants were asked to develop strategies for landing the rocket mentally; this, in turn, allowed the
patients to strategize ways
of blocking out hallucinatory voices inside their heads.
The
study, published today in the journal Trauma Surgery & Acute Care Open, found most
of the fictional
patients (71 %) were transferred from emergency directly to the operating theatre.
After
studying numerous
patients with circadian rhythms out
of sync, he hypothesized that their adrenal glands were overworked and producing lower levels
of the hormones needed to cope with stress.
This
study, published in the journal Philosophical Transactions
of the Royal Society B, found that 22
patients who played the memory game made significantly fewer errors and needed significantly fewer attempts to remember the location
of different patterns specific tests.
British - based GlaxoSmithKline, for example, conducts more than 100
studies a year in Canada, with the participation
of some 10,500
patients in more than 1,000 medical centres.
For example, a small
study of 38
patients with Alzheimer's from 2016 looked at the effects
of Victoza.
BIIB098: MRI and relapse results from the phase 3 EVOLVE - MS - 1
study in
patients with relapsing and remitting multiple sclerosis were presented at the 70th annual meeting
of the American Academy
of Neurology (AAN).
In a
study cited in Shawn Achor's book The Happiness Advantage, three groups
of patients treated their depression with medication, exercise, or a combination
of the two.
FITBIT DATA AIDS RESEARCHERS IN UNDERSTANDING SURGERY RECOVERY: Fitbit data can help researchers and doctors predict the risk
of 30 - and 60 - day readmission after surgery for cancer
patients, according to a
study published in the Annals
of Behavioral Medicine.
Scientists at the University
of Wisconsin and UCLA conducted the
study, which implanted electrodes deep into the craniums
of epilepsy
patients to monitor their brain activity during seizures.
The company points to a simple resource allocation problem that's hindered the most effective
patient care: the fact that it is physically impossible for oncologists to keep track
of every
study, every clinical trial, and every breakthrough in the wildly stratified world
of cancer research.
A recent
study tested 79
patients, outfitting one - third
of them with a VR headset depicting a coastal scene, one - third with a VR cityscape and the remaining third with no VR at all.
Speaking
of checkpoint inhibitor drugs... Merck's star cancer immunotherapy treatment Keytruda is facing some troubling clinical trial incidents which have now compelled the Food and Drug Administration (FDA) to halt three
studies of the drug in multiple myeloma, a rare blood cancer, after a number
of patient deaths.
To participate in the
study, which concludes in July 2020,
patients must be 18 years or older and have a histological - or cytological - proven diagnosis
of a malignancy in the lung, breast, head and neck, genitourinary organs or ovaries or multiple myeloma.
«If we add machine learning, the field
of study that allows computers to self - learn without specific programming to do so, to existing artificial intelligence (A.I.), the resulting machines will be better able to diagnose and heal
patients than their human counterparts can now,» he notes.
The
study offers more validation for the use
of remote
patient monitoring (RPM) wearables and devices to provide clinicians with fuller, more accurate
patient data.
The first step in the process is to surgically remove the
patient's tumor and ensure that the
patient is cancer free by confirming that there is no sign
of cancer on blood tests and imaging
studies.
Now, the firms are hoping that the completion
of the
study will show cardiovascular improvement in these
patients, giving them a strong argument to present to reticent physicians.
Besides randomized controlled clinical trials, there are a number
of ways researchers can
study how a particular cancer treatment is playing out in the real world: there are retrospective
studies, observational
studies, and even prospective research done using
patient registries.
The
study, just published in Science, showed that the creation
of what the researchers are calling microtumors can help predict drug effectiveness in cancer
patients better than the current standard method
of testing the drugs on rodents.
Other
studies, meanwhile, are examining tryp's potential efficacy as an antifungal agent; and as a prognostic indicator in
patients with brain cancer (as seen by increased uptake
of the amino acid on a PET scan).
«While we are disappointed CheckMate - 026 did not meet its primary endpoint in this broad
patient population, we remain committed to improving
patient outcomes through our comprehensive development program, including the ongoing Phase III CheckMate - 227
study exploring the potential
of the combination
of Opdivo plus [our other cancer immunotherapy] Yervoy for PD - L1 positive
patients, and Opdivo plus Yervoy, or Opdivo plus chemotherapy in PD - L1 negative
patients,» he added.
The
study, by Yusuke Tsugawa and colleagues at the Harvard T. H. Chan School
of Public Health, Harvard Medical School, and other institutions, examined the record
of a large random sample
of Medicare
patients, 65 years or older, who were hospitalized from January 2011 to December 2014.
The ENDEAVOUR Phase 3
study data monitoring committee recommended dosing be suspended after it found «an imbalance
of mortality» in
patients who used revusiran as compared to placebo.
«
Patients in the
study spent an average
of approximately 27 minutes per day exercising over the course
of an average 30 days in recovery,» wrote the researchers.
Amgen Executive Vice President
of Research and Development Sean Harper said the
study was designed to explore Kyprolis dosing regimens, noting that the the trial did not meet its goal in improving progression - free survival versus Velcade in
patients who had not yet been treated for the disease.
«ICU care is inefficient, devoting substantial resources to
patients less likely to benefit,» their
study, published in the February edition
of JAMA Internal Medicine, concluded.
An early, outsourced clinical research
study with real
patients was encouraging, but there are many potential pitfalls yet to come, said University
of North Carolina diabetes researcher Dr. John Buse, who was briefed by Google on the lens last week.
Khosla referenced a
study that asked a group
of doctors to review
patient data in order to determine whether the individual was in need
of cardiac surgery.
The company's first product, called Prevent, is an online version
of the Diabetes Prevention Program, a series
of interventions that grew out
of a National Institutes
of Health
study that looked at how diet and exercise could curb
patients» chances
of developing diabetes.