Sentences with phrase «of substantial variation»

We also have evidence of substantial variation in the quality of adult - child interactions in child - care settings.

Not exact matches

Landing page optimization is crucial when it comes to e-commerce, because the slightest variation of pricing, syntax and even design can cause substantial fluctuations in conversions.

Comments on the NPRM and various media reports together suggest that there is substantial variation in different firms» preparedness to comply with various provisions of the Fiduciary Rule and PTEs.

A lot of people say so based on myths and anecdotes, but an authoritative background study for the Mowat Centre Report on EI by Day and Winer found that «there is no evidence in the empirical literature that regional variation in the generosity of the employment insurance system has altered internal migration patterns in Canada in a substantial manner.»

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

An article in the March 15, 1999 issue of Restaurants and Institutions says that the cuisine of India will make a «substantial impact» on foodservice, and that because of the complexity of spice blends, it offers endless possibilities and variations.

Thirdly, there are substantial patterns of geographical variation in electoral support, as the regional distribution of votes reveals

The researchers also found that a substantial amount of genetic variation among individual warblers is associated with the different precipitation levels of their respective environments.

«The substantial variation in prescribing patterns of such extremely addictive medications for minor injuries results in many thousands of pills entering the community, and places patients at an increased risk of continued use and potentially addiction,» said lead author M. Kit Delgado, MD, MS, an assistant professor of Emergency Medicine and Epidemiology at Penn. «It's vital that we identify and understand the root causes of this growing issue.»

The results of the poll reveal substantial variation in how institutions handle postdoc affairs — not just because of the varying natures of the institutions, but because «we're all at different stages, doing different things,» Lakoski says.

There is little dispute that genetics accounts for a large amount of the variation in people's intelligence, but studies have consistently failed to find any single genes that have a substantial impact.

Fewer than half of U.S. schools have full - time nurses, with substantial variation by region, according to the data.

Although results from most of these studies do not find an increased risk, the results do show substantial variation, said Dr Jensen; this may be because of the limited size and follow - up time in most of them.

The lack of an optimal management strategy has led to substantial variation in the care for this vulnerable population, unnecessarily exposing many infants to potential harm.

The analysis also found that the chance of pregnancy was reduced in all age groups, with substantial variations between different cancer diagnoses — notably, reduced pregnancy rates in women with cervical cancer, breast cancer and leukemia.

Using occupancy modeling to control for variation in detectability, we show substantial (∼ 500 meters on average) upward changes in elevational limits for half of 28 species monitored, consistent with the observed ∼ 3 °C increase in minimum temperatures.

Table 1 also reports the percentage of spouses who died within a year after their own hospitalization; as expected, the diseases show substantial variation in lethality, with one - year death rates varying from 7.3 percent (for women with psychiatric disease) to 82.0 percent (for men with pancreatic cancer).

Quantifying the value of E accurately is difficult, and the variation across the models is substantial, primarily reflecting our incomplete knowledge of aerosol forcing.

There are substantial multi-decadal variations in the Pacific sector over the 20th century with extended periods of weakened (1900 — 1924; 1947 — 1976) as well as strengthened circulation (1925 — 1946; 1976 — 2005).

Currently, primary hepatocytes are the most common cell model, but their utility is fundamentally constrained by the substantial variation between donors and the finite number of cells that are harvestable from each donor.

Our analyses reveal that a substantial fraction of the genome - wide variation that is present in domesticated horses is not present in Przewalski's horses.

There is substantial international variation in mortality rates after treatment for abdominal aortic aneurysm, or enlargement of the aorta.

The list therefore contains some substantial specimens (OH9, 12 and 13), which are all way, way outside the morphological range of variation of modern humans, as well as some pretty insubstantial ones (OH11, 14 and 15) which I have not seen, and I bet no - one in AiG has seen — at any rate, if AiG have any evidence to dispute Tobias's assessments of them, then they are not letting on.

This same study revealed large inter-locus variation in cline width and cline center among some loci, consistent with substantial variation in patterns and levels of introgression as indicated by previous work [21], [24]--[26].

These results highlight the paradox of why substantial variation is observed in only a subset of epitopes.

The hamstrings did not record any substantial activation in any of the variations.

«Between the two extremes (high - vegetable, low - meat diet [s] versus high - meat, low - vegetable diet [s]-RRB-, a risk ratio of about 8 appears to exist, sufficient... to explain a substantial part of [that] international variation in the incidence of colorectal cancer.»

* A versatile, substantial layer that offers year - round comfort * Made from soft, certified organic cotton * Woven with jacquard stripes and then washed to create its undulating look and inviting texture * Due to the sand - washed nature of this bedding, slight variations in color will occur * Portugal Twin: 72» x 94» Double: 88» x 94» Queen: 94» x 98» King: 112» x 98» Standard Sham: 20» x 26»

Some of the choices lead to short added scenes, while others create more substantial variations.

Consistent with other research on school effects, we find that the school a student attends can explain a substantial share of the overall variation in test scores: that single factor explains 34 percent of the variation in math scores and 24 percent of the variation for reading.

Nevertheless, even the most conservative of our three methodological approaches suggests substantial variation in principal effectiveness: a principal in the top 16 percent of the quality distribution will produce annual student gains that are 0.05 standard deviations higher than an average principal for all students in their school.

The basic statistical models, which include the level of income, the quantity of schooling, and population growth rates, explain a substantial portion of the variation in economic growth.

Given the substantial variation in motivation and engagement throughout the school day and between students, we conclude every moment of every day for every student matters.

This analysis makes clear that large differences in the performance of high - SES students and low - SES students in the same schools do exist; that these apparent gaps are not simply reflective of gaps in preparation; and that while the variation across school districts is substantial, the variation within school districts may be even larger (at least among the largest districts in Florida).

According to Bhagat, one of the difficulties in implementing an inquiry - based teaching approach is that there is substantial variation in what educators mean by inquiry - based teaching, and a lack of understanding of the skills required to help students generate their own inquiries and guide, rather than direct the investigation that follows.

[5] At the beginning of the study period in 2001, there was substantial variation in quality across charter schools and, on average, charter schools in Texas were less effective than traditional public schools.

Appendix Figure 2 shows the substantial difference in average net prices charged to low - income students (publics charge substantially less, on average), although there is greater variation in the distribution of prices across private, non-profit colleges.

All district leaders believe that they focus on instruction, but we found substantial variation from district to district in the levels of skill and understanding with which they address this focus.

However, the variation in the impact of being so assigned was substantial.

But while assessment tests were standard practice, there was substantial variation in the types of other measures used across colleges and across subjects.

Murphy and Hallinger note, however, that there was substantial variation among their small sample of superintendents in how these functions were enacted, and they caution about the absence of corroborating data from their interviews.

A key consideration with much of this research is the substantial amount of variation in effectiveness within each approach to school improvement.

An initial review of the 1201 (a) MOE certifications revealed that that there is substantial variation among the States in the way they calculated and certified to their planned level of effort regarding State funding for the types of projects that are funded by the Recovery Act for the statutory period of February 17, 2009 through September 30, 2010.

Differences in advisors» beliefs affect not only their own investment choices, but also cause substantial variation in the quality and cost of their advice.

This substantial input of variation from wild ancestors has provided the raw material for phenotypic change, but unique development and genetic mechanisms may also have assisted the course of artificial selection.

``... the ecological and conservation significance of these kill tallies is difficult to contextualise, because (1) there are no reliable estimates of the total population of birds in Australia; (2) predation may fall disproportionately on some bird species; (3) some bird species may be able to sustain high mortality rates and maintain viable populations but others may not; and (4) as demonstrated here, there is substantial spatial variation in the numbers and proportion of birds killed across Australia.»

There was also substantial variation across breeds in the number of inherited disorders (median 32.5, range 10 — 77) and longevity (surveys: median 11.45 years, range 6.3 — 14.3; veterinary hospital records: median 6.5 years, range 3.5 — 9.1).

We only have direct observations of total solar irradiance (TSI) since the beginning of the satellite era and substantial evidence for variations in the level of solar activity (from cosmogenic isotopes or sunspot records) in the past.

For cause and effect: You never know, but I don't think that cloud cover regulates the sun cycle... Globally, the variation of cloud cover during a sun cycle is around 2 %, which can have a substantial influence on global temperatures.

The study, described in an article today in The Times, finds that poorly understood variations in water vapor concentrations in the stratosphere were probably responsible for a substantial wedge of the powerful warming trend in the 1990s and a substantial portion of «the flattening of global average temperatures since 2000 ″ (to anyone who hates talk of plateaus and the like, those are the authors» words, not mine).