Sentences with phrase «of synapse»

A big step in that direction took place in December when the development arm of Synapse Capital closed on the purchase of a 9,900 - square - foot lot in Harlem.

I've spoken highly of Synapse 2.0 in the past for its intuitive interface and wealth of options, and it's still one of the best gaming - peripheral software packages on the market.

The versatility of the Synapse 2.0 software also supports real time updates and opens the door to backward compatibility of additional legacy products.

Last week, a team of Synapse staff members led by Dr. Elizabeth A. Stanton released a report detailing least - cost strategies for RGGI states to reduce emissions 40 percent below 1990 levels by 2030.

Panelists will include authors of the Synapse report Air Emissions Displacement by Energy Efficiency and Renewable Energy, a survey of evidence that renewable resources and energy efficiency have indeed displaced fossil fuel resources connected to the grid.

In 2014 she was the Curatorial Fellow at La Box, ENSA in France, and became a member of the SYNAPSE International Curators» Network of the Haus der Kulturen der Welt in Berlin in 2015.

Khaled Jarrar's film, «Infiltrators» (2012), which portrays the struggle of Palestinians in the face of Israeli checkpoints, will be shown at the Athens Biennale 2015 - 2017 «OMONIA» final opening of Synapse 2.

Nabil and Manuela met in 2013's edition of SYNAPSE at HKW Berlin in the context of The Anthropocene Project.

Some of the painted imagery, which is often repeated and presented in a square snap - shot format, reads like transient thoughts or obsessions, a snippet of the synapse between art and life.

Control is handled through Razer Synapse, and I actually had some issues here: The 3.0 beta version of the software would see the Basilisk mouse I was testing at the time but not the keyboard, while the non-beta version of Synapse would detect the keyboard but not the mouse.

Almost always found on lists of «VHS horror movies that need Blu - ray releases,» Stephen Carpenter and Jeffrey Obrow's 1987 creature feature The Kindred is finally headed to DVD and Blu - ray courtesy of Synapse Films.

Bear with me: this couldn't be worse than Michael Bay's plan for another trilogy of synapse - smashing giant robot attack movies starring Mark Wahlberg.

Aβ is believed to penetrate neuronal plasma membranes, where it leads to lipid peroxidation.10 It has also been implicated in deactivating a subunit of the pyruvate dehydrogenase complex, thereby inhibiting conversion of pyruvate to acetyl CoA and the eventual production of cellular energy as ATP.32 Another way Aβ affects glucose metabolism in the brain is that fragments of Aβ disrupt insulin signaling by binding to neuronal synapses, which alters their shape and function.15, 38 Insulin receptors are abundant at synapses, so if the integrity of the synapse itself has been compromised, the receptors won't function effectively.

Regular sugar consumption also inhibits the action of the dopamine transporter, a protein which pumps dopamine out of the synapse and back into the neuron after firing.

Specific effects in response to changing nutrient availability at the level of the synapse has not been reported before.

Molecular Physiology of the Synapse Laboratory, Biomedical Research Institute Sant Pau (IIB Sant Pau), Sant Antoni Maria Claret 167, 08025 Barcelona, Spain.

Beth Stevens, PhD Assistant Professor FM Kirby Neurobiology Center Boston Children's Hospital Harvard Medical School Immune Mechanisms of Synapse Loss in Health and Disease

The AgedBrainSYSBIO consortium is coordinated by the French National Institute for health and medical research (Inserm, Prof. Michel Simonneau) and brings together an scientists with internationally recognized expertise in systems biology of the synapse and four small to medium size enterprises (SMEs) with a leading role in the project to assure the innovation potential and translation of project results to clinical application.

«There are many diseases that are diseases of the synapse: schizophrenia, depression.

In effect, the more that one side of the synapse «talks,» the better the other side «listens,» and the more effective the communication becomes.

These effects lead to loss of synapse

The hypothesis is that astrocytes play a crucial role in dictating synapse formation and function via the release of specific proteins that determine the type of synapse that will form, and the strength of that synapse.

Researchers have constructed a new detailed map of the three - dimensional terrain of a synapse — the junction between neurons which are critical for communication in the brain and nervous system.

These data substantially increase existing knowledge of synapse protein phosphorylation and support a model where the synapse phosphoproteome is functionally organized into a highly interconnected signaling network.

This project will increase our fundamental knowledge of the synapse and will shed light on the physiopathology of several neuropsychiatric illnesses in which synaptic defects are at the core of the disease.

Anna Huttenlocher, University of Wisconsin, USA Neutrophils in the Tumor Microenvironment Neutrophils, Wounds, and Cancer Progression Stefan Kaufmann, Max Planck Institute, Germany Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis Constitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells Kathryn Moore, New York University, USA MicroRNA -33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis Lalita Ramakrishnan, University of Cambridge, UK Myeloid Growth Factors Promote Resistance to Mycobacterial Infection by Curtailing Granuloma Necrosis through Macrophage Replenishment Beth Stevens, Harvard University, USA Microglia: Dynamic Mediators of Synapse Development and Plasticity Do glia drive synaptic and cognitive impairment in disease?

Our lab is interested in identifying the cellular and molecular mechanisms involved in the organization and maintenance of the synapse with a specific focus on the control of neurotransmitter receptor expression and localization.

When the researchers looked on a network level, they found that many of the genes that were found to be mutated in patients had a clear connection with the function of the synapse.

When the growing nerve fiber and the target cell finally come in contact, the provisional adhesion consolidates into the structural and functional organization of the synapse.

The two most studied forms of such modification are long - term potentiation, which is a strengthening of a synapse, by an increase in the transmission of signals through a synapse, and long - term depression, which is a weakening of the synapse.

By taking measurements on each side of a synapse leading into the cerebral cortex, the team could measure when neurons were firing, the strength of the signal and the signal - to - noise ratio.

The scientists created a molecular sensor for BDNF and showed that mimicking the signal associated with learning caused the release of BDNF from the receiving end of the synapse.

It ensures that the cellular debris is isolated from the rest of the synapse.

The compound prevented the impairment of the synapse.

Firing may trigger connected neurons to fire, too, depending on the weight of the synapse between them.

If the neurons it connects fire in close sequence more frequently when driven by data than when they are firing randomly, the weight of the synapse is increased by an amount proportional to the difference.

Interestingly, Sharma says, the team found that LRP6 was only found on a specific kind of synapse known as an excitatory synapse, suggesting that it enables the Wnt pathway to tailor its effects to just one synapse type.

To address this question, the researchers made use of mice with mutations that affect different aspects of synapse unsilencing.

However, studying the general mechanisms of synapse formation and distribution in dendrites has been challenging due to a lack of reliable methods that trigger and monitor synapse formation.

This phenomenon, known as long - term potentiation (LTP), occurs following persistent, high - frequency stimulation of the synapse.

«If you have high levels of this synapse - building, inflammation - regulating protein, you may not have as much, if any, change in your memory,» he said.

To investigate how synapses are strengthened, Littleton and Cho studied a type of synapse known as neuromuscular junctions, in fruit flies.

Chemical synapses, which are the most abundant type of synapse, can be either excitatory or inhibitory.

The findings of the study will prove invaluable to other research studies examining the role of synapse function in the diagnosis and treatment of neurodegenerative and other diseases.

That prion aggregates until it stops, changing the structure of the synapse in a way that should last for a very long period of time, perhaps decades.»

Researchers have observed AMPA traveling from the inside of a neuron to the downstream end of a synapse, but they remain uncertain as to whether the migration into and out of the synapse is the major component in determining synaptic strength.

The pair devised 10 differential equations to track the rate at which AMPA moves around into and out of the synapse.

The newly discovered Merkel cell - nerve ending synapse is unique, Gu says, «because it is the only example of a synapse formed between a non-neuronal cell and a nerve cell, and it is the first synapse that is found underneath the skin.»

Functionally, docking sites limit the maximum number of vesicles that can be released at each action potential, this determines the strength of the synapse.

Results showed that after the reminder of the fear and after the test for fear relapse, those mice given alcohol had many more GluR1 receptors with phosphates at the edge of the synapse than did mice given only water.