Sentences with phrase «of synaptic connections»

Synaptic plasticity, the ability of neurons to alter the strength of their synaptic connections with activity and experience, is thought to play a critical role in memory storage.

One study concluded that magnesium threonate increases the number of synaptic connections between brain cells and boosts the density of synapses (30).

Last year, Gladstone scientists announced a promising new drug candidate that prevents memory deficits and the loss of synaptic connections between brain cells — key features of Alzheimer's — in mice modeling the disease.

Learning and memory have been closely linked to strengthening of synaptic connections between neurons (i.e., synaptic plasticity) within the dentate gyrus (DG)- CA3 - CA1 trisynaptic circuit of the

«After a year of sound deprivation, we observed dramatic changes in the inner ear — notably, a significant loss of the synaptic connections through which the sensory cells send their electrical signals to the brain,» Dr. Maison said.

The human brain contains as many as 100 billion neurons, most of which make hundreds to thousands of synaptic connections with specific target cells.

This targeted electrical stimulation changes the strength of synaptic connections in the brain, resulting in improved health and function after a brain or spinal cord injury.

The same information can be represented as lines on paper, as electrical charges inside a PC's memory banks or as the strength of the synaptic connections among nerve cells.

«Collectively, our recent work offers significant evidence that RPM - 1 coordinates how long an axon grows with construction of synaptic connections,» said Grill.

Amidst the astounding complexity of the billions of nerve cells and trillions of synaptic connections in the brain, how do nerve cells decide how far to grow or how many connections to build?

In the brain, MeCP2 is found in high concentrations in neurons and is associated with maturation of the central nervous system and the formation of synaptic connections.

Further experiments showed that the protein inhibits the synthesis of molecules responsible for the stabilization of synaptic connections.

The so - called musashi protein is responsible for the structure and function of the synaptic connections of the brain, the place where information is communicated from one neuron to the next.

When synaptic connections were made, researchers observed that the distribution of Tau was 50 % more efficient than in the absence of synaptic connections.

In fact, it is generally accepted that a loss of synaptic connections leads to a loss in cognitive skills.

They are exploring whether these developmental findings can be used to address diseases such as stroke, by promoting the repair of synaptic connections following injury.

The CREB gene produces biochemical changes that facilitate the development of synaptic connections, which ultimately contribute to the formation of long - term memories.

In 2011, Professor Denk reported his breakthrough: there was indeed asymmetry in the numbers, or density, of synaptic connections made between pairs of starburst amacrine cells and retinal ganglion cells that were responding to a directional light signal.

This also works the other way round: as soon as the activity level exceeds an upper limit, the number of synaptic connections is reduced to prevent any overexcitation — the neuron firing rate falls.

The brain's neural circuits are established early during development, with milestones including the creation and migration of neurons, the formation of synapses — the pathways by which the neurons carry their electrical signals — and the strengthening of those synaptic connections.

«There is mounting evidence that the cellular machinery that controls cell death also controls the strength and number of synaptic connections,» Overstreet - Wadiche said.

A transient experience — one source of our memories — is capable of producing an enduring change in the strength of the synaptic connection, says Si.

The findings offer support for Tonegawa's new hypothesis that the strengthening of synaptic connections, while necessary for a memory to be initially encoded, is not necessary for its subsequent long - term storage.

«There is mounting evidence that the cellular machinery that controls cell death also controls the strength and number of synaptic connections»