Sentences with phrase «of synaptic density»

«This opens the door to follow the natural evolution of synaptic density with normal aging and follow how drugs can alter synapses or synapse formation.»

«Up to now any measurement of synaptic density was postmortem.»

Not exact matches

Li Li said: «For the first time, we have shown that visual learning can increase the density of nerve connections in this area of the brain and that an enriched environment, where bees are exposed to many colours without learning anything from them, can also affect the synaptic organisation in the brain.»

Bees with a greater density of nerve connections (known as synaptic complexes) in a specific part of their brains had better memories and learned faster than bees with fewer connections in these areas.

Additional experiments showed that bees that learned faster (shown by taking fewer landings to find the right flowers) also had a higher density of synaptic complexes in the visual association area.

With this noninvasive method, researchers may be able to follow the progression of many brain disorders, including epilepsy and Alzheimer's disease, by measuring changes in synaptic density over time.

For their study, the research team set out to develop a method for measuring the number of synapses, or synaptic density, in the living brain.

Along the long axis of PFs, the CB1 was localized at a much higher density on the perisynaptic membrane than on the extrasynaptic and synaptic regions.

APPsα, but not APPsβ, efficiently rescued deficits in spine density, synaptic plasticity and spatial memory of mice lacking both APP and APLP2 (cDKO).

mThy1 - AS mice administered only control IgG1 suffered dendritic atrophy (as suggested by reduced staining with MAP2) and synaptic loss (evaluated with postsynaptic density - 95 (PSD - 95) and synaptophysin) across several regions of the brain, but this neurodegenerative damage was substantially prevented in mice administered 1H7, 5C1, or 9E4.

Mice genetically engineered to lack PirB, or treated with an infusion of soluble PirB directly into the brain, also showed an increase in synaptic density and signalling in the visual cortex.

Within synapses, more specifically in areas of postsynaptic density (PSD), there is a high concentration of proteins that receive and transduce synaptic information.

One study concluded that magnesium threonate increases the number of synaptic connections between brain cells and boosts the density of synapses (30).

''... we hypothesize that repeated stress - related allostatic overload may affect brain function at three basic levels: (a) at the cellular level, it may compromise proteostasis (e.g. tau protein), organelles homeostasis, and induce epigenetic changes in neuronal DNA; (b) at the tissue level it may affect intracellular communication (synaptic contacts), number of cells (reduction of neuronal density), composition of the extracellular matrix (accumulation of amyloid plaques), and neuroinflammation; (c) at the systemic levels it may alter the brain's regulation of behavior (cognitive decline).

Both hippocampal synaptic density and LTP as well as contextual fear conditioning and spatial learning vary as a function of maternal care in the rat [10], [15].