The kinase activity of RIPK1 mediates hypothermia and lethality in a mouse model of TNF - induced shock, reflecting the hyperinflammatory state
of systemic inflammatory response syndrome (SIRS), where the proinflammatory «cytokine storm» has long been viewed as detrimental.
Conejero, R., Bonet, A., Grau, T., Esteban, A., Mesejo, A., Montejo, J. C., Lopez, J., and Acosta, J. A. Effect
of a glutamine - enriched enteral diet on intestinal permeability and infectious morbidity at 28 days in critically ill patients with
systemic inflammatory response syndrome: a randomized, single - blind, prospective, multicenter study.