FDA medical officer Frances Oldham Kelsey averted the tragedy
of thalidomide birth defects in the United States
Holmes also notes that the relative paucity
of thalidomide births in the United States means that few researchers there can speak with authority on the drug's effects.
Not exact matches
Meanwhile, reports
of startling
birth defects in babies born to mothers who had taken
thalidomide were surfacing in Germany, Australia and other countries where the drug was legal — including Kelsey's native Canada.
If you look at the original work on the epidemiology
of thalidomide [a morning - sickness drug that turned out to cause
birth defects], there were specific time points where, if the woman was exposed, the baby had a high probability
of having bona fide autism.
The prime example is
thalidomide, which was outlawed in the 1960s because it caused
birth defects but has now found a niche in the treatment
of cancer and leprosy.
To test the potential
of the system as a drug - screening tool, the researchers exposed the differentiating cells to
thalidomide, a drug known to cause severe
birth defects.