Sentences with phrase «of the actin cytoskeleton»

Her laboratory focuses on the roles of the actin cytoskeleton in cell architecture and physiology in organs such as muscle, blood and eyes.

In contrast, injection of bacterial cells of the insect pathogen Photorhabdus leads to a rapid «freezing» phenotype of the hemocytes associated with significant rearrangement of the actin cytoskeleton.

Role of actin cytoskeleton in cell migration.

The gene discovered in the research couples the exocytosis - regulating protein Sec10 with formin, a protein that regulates the remodeling of the actin cytoskeleton critical to forming cell shapes.

In general, he focused on GTPases, exploring a wide range of biological roles, with a major emphasis on neutrophil chemotaxis, the NADPH oxidase burst in leukocytes and regulation of the actin cytoskeleton.

Further, they linked the chemical reactions of the different molecules to the reorganization of the actin cytoskeleton, which gives the cell its shape.

High curvature also induces a circumferential alignment of the actin cytoskeleton, stabilized by multiple focal adhesions.

The Golgi comprises a paired stack that is separated at G2 by modulation of the actin cytoskeleton through Abi and Scar: WAVE Developmental Cell 12:901 (2007)

This process implies a partial cell depolarization and the acquisition of a motile phenotype that involves rearrangements of the actin cytoskeleton.

This step requires remodeling of the actin cytoskeleton and the expression of exploratory, sensory organelles known as filopodia.

Specifically, the team hypothesizes that microRNA miR - 24 is a key regulator of actin cytoskeleton dynamics (i.e. the inner structural support of a cell); therefore, it plays a critical role in regulating multiple disease processes, including the angiogenesis (blood vessel growth), inflammation, and fibrosis (thickening and scarring of tissue) associated with choroidal neovascularization (CNV) in wet AMD.

The broad objective of our research is to understand how epithelial cells interact with their microenvironment during migration, focusing on the mechanism of cell migration and the role of actin cytoskeleton in this process.

These results show that in non-transformed cells, S1P induces a rearrangement of the actin cytoskeleton and stimulates proteolytic activity on cell surfaces.