Sentences with phrase «of the amino acid residues as»
SAR studies performed on FC131 analogues, such as modification of the amino acid residues as well as ring structures and backbones, indicated that a defined spatial arrangement of the functional groups on the side chain is necessary for the activity of such compounds.
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As a result of the mutational analysis, an amino acid residue of the JUNO protein, 62th Tryptophan (W62), was determined to be essential for the interaction with IZUMO1.
«NMR enabled us to obtain additional information such as which amino acid residues form salt bridges thus enhancing the stability of the fibrils,» explains Prof. Henrike Heise from Heinrich Heine University Düsseldorf and Jülich's Biomolecular NMR Center.