Sentences with phrase «of the amino acid sequence in»

Instead, biologists may have to understand and control variations, or codes, of amino acid sequences in the protein that apparently guide them to engage in certain kinds of assemblies and prevent droplet assemblies from turning into tangled knots.

Grains probably being number one trigger becau — partly because of the amino acid sequence in the grains, I very similar to the surface proteins of the thyroid.

Not exact matches

biochemical evidence such as Cytochrome - cyto - C is just one of the thousands of sequences and is not proof of common ancestry, as there are more variations than similarities in the genetic code, on the other hand a study of the amino acid make - up reveals that man is closer to lamprey than are fish.

Biochemists found out how to determine the sequences of amino acids in proteins.

There is no such «direct» evolution: animals, bacteria, and algae have a common ancestor from which they have diverged, as can be shown by aligning and comparing amino acid sequences of proteins and nucleotide sequences of homologous ribosomal RNA molecules that are found in both bacteria and vertebrates.

I love biology, every pain staking detail of DNA - one mess up in an amino acid sequence and you get sickle - cell anima, or the proteins don't function correctly.

The major function of DNA is to encode the sequence of amino acid residues in proteins, using the genetic code.

The tools included TCRdist, which researchers used to calculate the similarity and differences of key features of T cell receptors, such as amino acid sequences in important regions for antigen recognition.

Molecular geneticist Cheng Chi Lee, developmental biologist Gregor Eichele, and their co-workers at the Baylor College of Medicine in Houston have isolated a gene in mice and humans that shares 44 % of the amino acid sequence of the period (per) gene of the fruit fly Drosophila melanogaster.

To create their code, the researchers tested out many amino acid combinations and found a particular set of amino acids that will bind each of the four bases at any position in the target sequence.

The shape in which a protein naturally folds is known as its native state, which is determined by its sequence of amino acids.

It persists, in large part, due to continual changes in the sequence of amino acid «building blocks» that make up the viral protein hemagglutinin, enabling it to avoid recognition and removal by immune system antibodies.

Naturally occurring peptides can be composed of 20 different amino acids, so there is a great deal of possible variation in their sequences.

The genetic code is the set of rules by which information encoded in genetic material (DNA or RNA sequences) is translated into proteins (amino acid sequences) by living cells.

As the authors of the new research explain: «There are three main levels of analysis in the study of proteins: the first is the sequence of amino acids, the second is the three - dimensional structure that these filaments take on a very short time after they are synthesized, while the third regards their function.

They found that the proteins of prokaryotes (the group of organisms that includes bacteria and blue - green algae) tended to have sequences of about 150 amino acids, or a multiple of that number, while the proteins of the eukaryotes (which account for all other organisms) had amino acid sequences in multiples of around 125.

Chemical analysis of the protein yielded seven sequences of about 10 to 20 amino acids in length.

Critics also noted that one of the six amino acid sequences reported in the 2007 paper was misassigned and is likely incorrect.

Astrochemists have already spotted signs of amino acids in space as well as sequences of molecules that might have given rise to them.

«Genes code for the sequence of amino acids in proteins, and some are involved in the regulation of the expression of other genes,» he says.

They found that one small section of the toxin is «highly conserved,» meaning that its sequence of amino acids is identical to the same sequence in other Clostridium species.

By generating the sequence of one Neandertal and 50 present - day humans at these positions, we have identified 88 amino acid substitutions that have become fixed in humans since our divergence from the Neandertals.

By March 2014 — about the time the epidemic was detected, but some 3 months after the first case actually occurred — the sequences had split into two distinct lineages, one of which was characterized by a single amino acid change in a region of the virus's surface protein and allows it to bind to cells.

When they compared the amino acid sequence of naked mole rat protein, the researchers found that three of these protein building blocks were different from the rat version and one was also different from the same protein in other mole rats.

Most orthology determination methods make use of sequence comparisons: the amino acid sequences of all proteins in two species are compared with each other, and the two sequences that are most similar are considered to be orthologs.

Additionally, colleagues from the Washington University in St. Louis predicted the sequences of the amino acids responsible for Sup35 sensing changes in the cytoplasmic pH value.

Variations in N - CAM activity thus do not occur by changes in the amino acid sequence that alter the specificity of binding.

They looked for those that were triggered to release oxygen by bicarbonate ions, and found that human haemoglobin behaved like its counterpart in crocodiles if it contained a particular sequence of just 12 amino acids from the crocodile's haemoglobin.

Cloning and sequencing of complementary DNA's from normal and WHHL rabbits, shows that this defect arises from an in - frame deletion of 12 nucleotides that eliminates four amino acids from the cysteine - rich ligand binding domain of the LDL receptor.

Just as the letters of the alphabet can be combined to form an almost endless variety of words, amino acids can be linked in varying sequences to form a huge variety of proteins.

Dan Graur of Tel Aviv University bases his surprising claim on a study of genetic mutations, which produce changes in the amino acid sequence of the protein a gene codes for, and which are assumed to accumulate at a fairly steady rate.

Starting in the late 1980s, their labs revealed steps in how the endoplasmic reticulum, the cell's factory for processing secreted and membrane proteins, deals with proteins whose linear sequence of amino acids hasn't folded into a proper 3D shape.

Prions can exist as distinct strains — proteins that have the same sequence of amino acids but misfold in different ways and have distinct biological behaviours, much as different strains of a pathogenic virus can be aggressive or weak.

This work led to Inz - 5, which exhibited dramatically improved potency and selectivity for fungal cytochrome B. Although cytochrome B is highly conserved across humans and many pathogenic fungi, including Cryptococcus neoformans, Aspergillus fumigatus, and Rhizopus oryzae, Inz - 5 exploits important differences in the amino acid sequence of the protein that enable selectivity for fungi.

They characterized the set of HA mutations required to increase the preference of the viruses for human receptors, discovering that only a single amino acid change in the HA sequence is necessary for this to occur.

Then he used a computer to compare the string of amino acids making up the protein to the sequence of amino acids in all other known proteins.

Researchers studying a protein that causes a hereditary degenerative brain disease in humans have discovered that the human, mouse and hamster forms of the protein, which have nearly identical amino acid sequences, exhibit distinct three - dimensional structures at the atomic level.

Collins already had developed a method to identify ancient species by differences in the amino acid sequences of collagen and other proteins preserved in fossils.

When the researchers checked a database with genome sequences of more than 6000 flu virus variants, they found that the amino acid sequence of this region remains constant in many viral strains.

Samples of the virus were sent to the US Centers for Disease Control and Prevention (CDC) in Atlanta, where analysis of amino acid and RNA sequences revealed that it is closely related to the deadly Hendra virus, first isolated in Brisbane in 1994.

In its first phase, the money was distributed between nine structural - biology research consortia, each of which would go on to produce dozens of protein structures per year — with the lofty goal of eventually predicting structures for most of the amino - acid sequences possible in naturIn its first phase, the money was distributed between nine structural - biology research consortia, each of which would go on to produce dozens of protein structures per year — with the lofty goal of eventually predicting structures for most of the amino - acid sequences possible in naturin nature.

With the large quantities of NGF made available by their technique Ruth Hogue Angeletti and Ralph A. Bradshaw of the Washington University School of Medicine were able to determine the sequence of amino acids in the protein.

A comparison of the sequence of amino acids in NGF with that of several other polypeptides by William A. Frazier of Washington University revealed that NGF and insulin have certain sequences in common.

Although this intriguing possibility remains theoretical, the similarities in the amino acid sequences of NGF and insulin are not great enough to result in any similarity of function: the two molecules have completely different target cells and biological activities.

Genome sequencing of six children with autism has revealed mutations in a gene that stops several essential amino acids being depleted.

Modern molecular technologies (genomics and other omics), through comparing nucleic acid and amino acid sequences across living species, are enabling the identification of genetic components and patterns stingily conserved by evolution, from those in which times of evolutionary branching of the tree of life can be inferred.

The alignment encompasses a substantial part of C. elegans and human sequences (e.g., 90 % of W01A8.1 and 87 % of Perilipin 2) and covers all three domains characteristic for perilipins (N - terminal PAT, imperfect amphiphilic 11 - mer repeat (Brasaemle, 2007) and C - terminal four - helix bundle (Hickenbottom et al., 2004)-RRB- covering approximately amino acids 10 — 100, 125 — 190 and 220 — 380 respectively in W01A8.1 a.

Delbrück's summer course on bacteriophages in 1945 at Cold Spring Harbor in New York set in motion the chain of events that led to understanding the genetic code by which the sequence of the nucleotides in DNA is translated into the sequence of amino acids in a protein.

Compared to the pNL4 - 3 reference sequence (GenBank: AF324493), this plasmid contains a four nucleotide insertion (TCGA) resulting in a stop codon after amino acid 46 of Nef.

The discovery is unusual because the enzymes do not bear a resemblance — in their structures or amino - acid sequences — to any known class of enzymes.