Sentences with phrase «of the cell line at»

To settle the case, they analyzed the genetic sequence of the cell line at 500,000 locations across the genome.

Not exact matches

Babies have very sensitive stomachs; in fact, the cell lining of a baby's stomach is not equipped to handle any solid foods until at least 4 months of age, when gut enzymes have also started producing to help aid in digestion.

Jose E. Garcia - Arraras, a biology professor at the university's biology research center on the Río Piedras campus, said a power plant designed to keep scientific samples refrigerated broke down and the roof of a critical building gave way to flooding, rendering «samples, libraries, cell lines, etc. lost.»

«Our study results are the first to argue that we may be able to treat inflammatory bowel disease and protect against transplant rejection not only by blocking TNF alpha as is done currently, but also by stimulating ATG16L1 to prevent early death of cells lining the gut,» says study senior investigator Ken Cadwell, PhD, an associate professor at NYU School of Medicine and NYU Langone Health's Skirball Institute for Biomolecular Medicine.

In 2007, however, scientists at International Stem Cell, a California - based biotech firm, reported the first successful creation of human stem cell lines from unfertilized eCell, a California - based biotech firm, reported the first successful creation of human stem cell lines from unfertilized ecell lines from unfertilized eggs.

That was the dogma until a few years ago, when a group at Massachusetts General Hospital in Boston discovered stem cells tucked away in the protective lining of the ovary that mature into fresh eggs.

The year's most prominent science issue, federal support of embryonic stem cell research, is so controversial that the sons of Ronald Reagan gave dueling speeches at the opposing party conventions; Michael Reagan backs President George W. Bush's policies, including the ban on funding for research on new stem cell lines, while Ron supports Senator John Kerry's promise to lift restrictions.

Instead of presenting electronic content one line at a time, this display would translate words and images into tactile displays consisting of up to 25 rows, each with 40 cells side by side.

Of people seeking access to biomaterials referred to in published work (such as the cell lines, tissues, antibodies, and reagents), 35 % were denied access to these materials at least once in the last 3 years.

It is a smart filter at that: The cells lining the brain's blood vessels can build extra proteins for grabbing glucose if the brain needs a boost and can also destroy some of the proteins to dial the flow back down.

In addition, where cells derived from embryonic stem cells are great at proliferating — a potentially critical feature if one wants to grow sufficient numbers of cells for clinical use — ones from the iPS lines were much feebler.

According to Izpisúa Belmonte, who is also a professor at the gene expression laboratories of the Salk Institute for Biological Studies in San Diego, California, CMRB aims to become «a research centre of excellence in south Europe in the line of world - recognized institutions such as the Salk or the Whitehead institutes, where both pre - and postdoctoral researchers receive multidisciplinary training of the highest quality» in stem cell biology and cell regeneration.

Another problem is that in its July 2009 Guidelines on Human Stem Cell Research, NIH spelled out specific requirements about embryo donation for newly derived lines, says Pilar Ossorio, a legal scholar who studies research ethics at the University of Wisconsin Law School.

A special receptor on cells that line the sinuses, throat and lungs evolved to protect mammals from developing a range of allergies and asthma, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

The enzyme was tested in three different cell lineages: leukemia cells incapable of producing asparagine at normal levels (MOLT4); another line of leukemia cells, in this case capable of producing asparagine at normal levels (REH); and non-malignant cells, used as a control (HUVECs).

This work is being done in collaboration with Dr. Hasan Korkaya, assistant professor, Biochemistry and Molecular Biology at the Medical College of Georgia, who has developed drug - resistant cell lines, and with breast cancer clinicians.

Kenneth Ain, a thyroid cancer physician and researcher at the University of Kentucky, found that many of his cell lines were contaminated.

At perhaps 11,000 years old, CTVT is the oldest known line of mammalian cells on Earth, so it's no longer evolving much.

By carefully tracing a line of at least 2 millimeters outside of and around the edges of a mole that is suspected of being a cancer, doctors can remove all of its cells and avert the need for a second surgery.

A stem cell core facility at CHOP, directed by study co-author Deborah French under the auspices of the hospital's Center for Cellular and Molecular Therapeutics, generated the iPSCs lines used in these studies.

«Most researchers have relied on cell lines to screen the effect of drugs and other treatments including viruses,» said Dr. Cripe, who also is a professor at The Ohio State University College of Medicine.

Ain attended the annual Endocrine Society meeting in Toronto, where Bryan Haugen, head of the endocrinology division at the University of Colorado School of Medicine, told Ain that several of his most popular cell lines were not actually thyroid cancer.

«The bottom line question,» says Christopher Austin, a neurogeneticist at Merck Research Laboratories in West Point, Pennsylvania, is whether this kind of gene therapy can stem the rate of brain cell death.

Until 2009, Saitou's starting point had been cells taken from a live mouse epiblast — a cup - like collection of cells lining one end of the embryo that forms at the end of the first week of development, just before the PGCs emerge.

The researchers also employed a cutting - edge technology developed by their collaborators at Columbia University to reprogram the child's skin cells into early progenitor cells, then differentiate those into lung cells, the front lines of influenza infections.

To address this question, the research teams from Berlin and Würzburg took a closer look at human colon carcinoma cell lines that innately show high levels of c - MYC.

For this study, a tumor cell line was transplanted into a rat and imaged with each of the following: conventional MRI, the radiotracer carbon - 13 (C - 13) pyruvate and hyperpolarized MRI at a resolution of 2.5 mm, Medipix positron detector, luminescence sensor and a fluorescence microscope.

With help from researchers at Duke University, they showed that the gene has a unique pattern of methylation in breast cancer cell lines that might one day help doctors spot the disease.

The dispute had to do with Mikovits's insistence that another scientist at WPI had improperly ordered a cell line for experiments that were beyond the purview of his authority.

Ana Soto, professor of cellular biology at Tufts University School of Medicine, and her colleagues were studying the effects of estrogen on a breast cancer cell line.

One cell line produced ten times more than any of the others, most produced very few, and some produced none at all.

As acting NIH Director Raynard Kington explained at a press conference, there will be separate channels for determining whether a cell line is eligible depending on whether it was derived before or after 7 July, the effective date of the guidelines.

Breast cancer researchers have mapped early genetic alterations in normal - looking cells at various distances from primary tumours to show how changes along the lining of mammary ducts can lead to disease.

At the University of Washington, Hannele Ruohola - Baker, professor of biochemistry and associate director of the Institute for Stem Cell and Regenerative Medicine, Julie Mathieu, acting instructor and Henrik Sperber, graduate student, withdraw embryonic stem cell lines from liquid nitrogen storCell and Regenerative Medicine, Julie Mathieu, acting instructor and Henrik Sperber, graduate student, withdraw embryonic stem cell lines from liquid nitrogen storcell lines from liquid nitrogen storage.

In 2008 a group of medical researchers led by Robert Lanza at Advanced Cell Technology in Worcester, Massachusetts, reported another leap: They discovered a way to avoid destroying the embryo by deriving an entire stem cell line from a single embryonic cCell Technology in Worcester, Massachusetts, reported another leap: They discovered a way to avoid destroying the embryo by deriving an entire stem cell line from a single embryonic ccell line from a single embryonic cellcell.

A team of researchers in Germany and Denmark led by Steven Johnsen, Professor at the University Medical Center Göttingen, Germany, used human prostate cancer cell lines and depleted them of the DNA - binding protein CHD1.

Cheng, an assistant professor of medicine in hematology / oncology at Feinberg, provided the cell lines and NanoFlare targets the researchers used to model blood samples taken from breast cancer patients.

They used the gene editing technology CRISPR to engineer a series of human embryonic stem cell lines, which were identical apart from the number of DNA repeats that occurred at the ends of their HTT genes.

Daniel Henk, now at the University of Bath, UK, and colleagues collected fungal cells lurking on the platforms at 12 stations across the three lines.

«Endothelial cells make up the inner lining of blood vessels,» said William Durante, Ph.D., professor of medical pharmacology and physiology at the MU School of Medicine and lead author of the study.

The research, the team said, should not discourage the pursuit of experimental treatments but instead be heeded as a call to screen rigorously all cell lines for mutations at various stages of development as well as immediately before transplantation.

Putting together their analyses of the mitochondrial DNA in each tumour cell line and the metabolic pathways at work, the team were able to deduce how each cell line's genetics directly affected its ability to multiply.

Derived mostly from human embryonic kidney 293T (HEK293T) and HeLa cell lines, EdiGene Knockout (KO) Cell Lysates have been optimized through the use of genome editing technology and validated at the genomic level through PCR and Sanger - sequencing techniques to ensure the accuracy and knockout of the target gcell lines, EdiGene Knockout (KO) Cell Lysates have been optimized through the use of genome editing technology and validated at the genomic level through PCR and Sanger - sequencing techniques to ensure the accuracy and knockout of the target gCell Lysates have been optimized through the use of genome editing technology and validated at the genomic level through PCR and Sanger - sequencing techniques to ensure the accuracy and knockout of the target gene.

Earlier approaches to creating this growth environment, pioneered by study co-author Jason Spence, Associate Professor of Internal Medicine at the University of Michigan, had used a natural matrix derived from a tumor cell line.

The far - reaching potential of iPS research, combined with a higher likelihood that cell lines will stay linked to a single donor (and that donor's health history), heightens the need for consensus, said Timothy Caulfield, research director of the Health Law Institute at the University of Alberta in Edmonton.

In the different cell types, the loops begin and end at different specific chromosomal locations, so each cell line's genome appears to have a unique population of loops.

«In future, the decoded hamster genome will greatly advance the use of cell lines to produce pharmaceuticals», says Noll, who runs the Cell Culture Technology research group at the Faculty of Technology and participated in the research projcell lines to produce pharmaceuticals», says Noll, who runs the Cell Culture Technology research group at the Faculty of Technology and participated in the research projCell Culture Technology research group at the Faculty of Technology and participated in the research project.

Researchers at the University of California, San Diego School of Medicine report that dietary capsaicin — the active ingredient in chili peppers — produces chronic activation of a receptor on cells lining the intestines of mice, triggering a reaction that ultimately reduces the risk of colorectal tumors.

The article, «The Genomic and Transcriptomic Landscape of a HeLa Cell Line,» by Landry et al., was authored by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and was published in an early online version March 11, 2013.

Now, researchers at the University of Missouri have shown that a new line of genetically modified pigs will host transplanted cells without the risk of rejection.