The
sequencing of the human genome in the year 2000 revealed how the 3 billion letters of A, C, G and T, that the human genome consists of, are ordered.
The goal
of the human genome project was to use DNA sequencing to reveal all three billion DNA letters in our chromosomes and find all our genes.
Scientists published the first
draft of the human genome nearly a decade ago, but the hunt for disease genes is far from over.
The publication
of the human genome in 2001 revealed its sequence — the significance of which remains a mystery.
Now an international team has applied this approach to tackle the wheat genome, which is five times the
size of the human genome and much more complicated.
The functional
portion of the human genome probably falls between 10 percent and 15 percent, with an upper limit of 25 percent, suggests new research.
Most of the sequencing
of the human genome by this international consortium has been done in just the last 15 months.
Going forward, it's easy to see how greater
knowledge of the human genome — knowing which gene does what as well as its precise location within the genome — has enormous potential.
If it does, then the future rewards
of human genome research will extend well beyond medicine and the linking up of genes and diseases.
Around two per
cent of the human genome acts as a blueprint for proteins, which work as molecular machines assuming important functions in the cells of our bodies.
Since the
publication of the human genome sequence in 2001, scientists have found that the so - called junk DNA that lies between genes actually carries out many important functions.
The scientists noted that the steady flow
of human genome data has been a boon to research and has not cluttered up databases with incomplete information, as some had feared.
DNA technology will continue to develop as we try to understand how the
elements of the human genome work and interact with the environment.
Previous studies on natural resistance to malaria had implicated a
section of human genome near to a cluster of receptor genes.
To gain a comprehensive
view of the human genome and biological systems, they instead had to work in a highly integrated fashion.
The sequencing
of the human genome involved hundreds of researchers around the world, with five centers taking on the lion's share of the work (see chart).
These data provide a study design that can be used to determine how variation in the sequence
of the human genome gives rise to human diversity.
«We need to know the functional
fraction of the human genome in order to focus biomedical research on the parts that can be used to prevent and cure disease,» he said.
In this
era of the human genome map, it would seem a simple matter to pinpoint the bit of DNA responsible for each disease and use that knowledge to find a cure.
Scientists are now contemplating the
fabrication of a human genome, meaning they would use chemicals to manufacture all the DNA contained in human chromosomes.
A team of scientists has developed an algorithm that can accurately pinpoint, in large
regions of the human genome, mutations favored by natural selection.
After scientists announced the first
draft of the human genome, people began to wonder how our new understanding of DNA would change life.
Surprisingly, the study also found that the genomes of Latino individuals are a uniquely powerful resource for assembling
maps of the human genome.
This story and the one accompanying it are part of a collection this month reflecting on the 10th anniversary of the
publication of the human genome, which are gathered here.
Phrases with «of the human genome»