Sentences with phrase «of the human genome gives»

These data provide a study design that can be used to determine how variation in the sequence of the human genome gives rise to human diversity.

Not exact matches

Then, given your clearly profound understanding of the relevant science, you can explain how humans came to possess a defunct gene for egg - yolk proteins in our placental mammal genomes and why the presence of this dead gene and the mutations rendering it defunct map to the lineages observable in the fossil record?

Given the enormity of the task and the projected budget of $ 3 billion spread out over a 15 - year period, the Human Genome Initiative is «big biology.»

If any part of the Human Genome Project is to be done at all, one might wish it were directed by someone who takes time off from scientific excitements to give careful thought to what it is that he and his colleagues are proposing to do.

«Anthropological reflection, in fact, leads to the recognition that, by virtue of the substantial unity of body and spirit, the human genome not only has a biological significance, but also possesses anthropological dignity, which has its basis in the spiritual soul that pervades it and gives it life.»

Given Britain's involvement in an international research consortium formed to create the most detailed and medically useful picture of human genetic variation to date, tonight's other discussion points include the scientific value of the information and the regulatory implications of providing public access to personal genome data through academic research projects, as well as through commercial organisations.

On average, every duplication of the human genome includes 100 new errors, so all that reproducing gave our DNA many opportunities to accumulate mutations.

Encased in ice for 4,000 years, a clump of prehistoric human hair gave up its secrets to the University of Copenhagen's Eske Willerslev, the first researcher to sequence an ancient human genome.

Researchers were able to determine the genome of stomach bacteria that infected the famous Iceman at the time of his death, in the process giving us clues about ancient human migrations.

He was fascinated by a talk one of his engineering professors gave about high - performance computing in the Human Genome Project, and he began to see other connections between biology and engineering.

«The Human Genome Project gave us a list of parts,» Vidal explains.

«This study gives deep new insights into the life of a parasitic fluke in the human bile duct, and was enabled by the development of an exciting new genome assembly tool called OPERA - LG in our lab.

Careful attention to phenotyping diseases, facilitated by our knowledge of the human genome and computational analysis, has allowed observant physicians and physician - scientists to identify and categorize diseases in a manner that has informed basic science, given it new contexts, and in many instances provided important new directions for investigation.

To identify the genes that give rise to the palette of human skin tones, Crawford et al. applied genome - wide analyses across diverse African populations (see the Perspective by Tang and Barsh).

DNA methylation is a biochemical alteration of the building blocks of DNA and is one of the markers that indicate whether the DNA is open and biologically active in a given region of the human genome.

«By itself, the human genome was not a recipe for new treatments,» he says, «but it gave medicine amazing amounts of basic, quantitative information to start from.»

At any given moment, the human genome spells out thousands of genetic words telling our cells which proteins to make.

That, too, is unusual, especially given that on the tree of life, even primitive anaerobic fungi, like the three that underwent genome sequencing in this study, are evolutionarily much closer to humans than to bacteria.

Given the outward differences, it seems reasonable to expect to find fundamental differences in the portions of the genome that determine chimp and human brains — reasonable, at least, to a brainocentric neurobiologist like me.

For instance, in the human genome we still see the remnants of the large olfactory receptor gene family that gave our evolutionary ancestors a keen sense of smell, even though humans no longer rely on them.

The sequencing of the human genome (ScienceNOW, 14 April 2003:) gave scientists major new insights into what makes us human: Although we share more than 98 % of our genetic code with the chimpanzee, natural selection has turned us into a very different animal than the chimps, from whom our hominid ancestors split evolutionarily some 6 million years ago (ScienceNOW, 31 August).

Although the Green et al. analyses are suggestive of admixture, the role of Neandertals in the genetic ancestry of humans outside of Africa was likely relatively minor given that only a few percent of the genomes of present - day people outside of Africa appear to be derived from Neandertals.

In a Philadelphia Inquirer op - ed, he wrote that such eternal life was in our reach because «Being able to decode the human genome allows us to develop detailed models of how major diseases, such as heart disease and cancer, progress, and gives us the tools to reprogram those processes away from disease.»

The study for the first time estimates the minimum number of locations in the human genome — 250 to 300 — where gene copy number variation (CNV) can give rise to autism spectrum disorder (ASD).

BETHESDA, Md., Wed., Oct. 5, 2005 - The National Institutes of Health (NIH) today announced contracts that will give researchers unprecedented access to two private collections of knockout mice, providing valuable models for the study of human disease and laying the groundwork for a public, genome - wide library of knockout mice.

Ultimately, given that we are able to detect little phenotypic impact where there are vast amounts of DNA turnover, our findings support lower estimates for the functional proportion of the human genome.

On Aug. 3, the scientific article in Nature finally gave us some facts about the much - hyped experiments that involved editing the genomes of human embryos at the Center for Embryonic Cell and Gene Therapy at Oregon Health and Science University.

«We believe that this type of multi-stakeholder discussion is necessary before proceeding, given the significant issues and concerns related to human germline genome editing,» he said.

«The time is right for pursuing the complex question of healthy aging given the rapid advances in analytical technologies and the expanding knowledge of the human genome and microbiome and their interactions.

Now, after a multi-year concerted effort by more than 440 researchers in 32 labs around the world, a more dynamic picture gives the first holistic view of how the human genome actually does its job.

Very good for giving the overview of the BioTech industry as it applies to the Human Genome sequencing race and the potential for use of this information in the future for Personalized Medicine.

The American Society of Human Genetics (ASHG) and the National Human Genome Research Institute (NHGRI) co-sponsor the Genetics and Public Policy Fellowship to give genetics professionals an opportunity to contribute to the policy - making process.

The total reagent costs for human genome sequencing is approximately 14 000 SEK given a 30 fold coverage of the human genome.

At the opposite end of the scale, Lee's other well - known series of work from the late 1990s gave gruesome shape to our worst biotechnological fears, in a period marked by hysteria over the Y2K bug, the start of the Human Genome Project, the commercialisation of genetically modified crops and the birth of Dolly the sheep.

In reality, we owe our existence to the power of the human genome and the perseverance, ingenuity and adaptability of our species and as our species has given life to each of us as individuals, so have we inherited the responsibility to ensure that our species continues to live in a healthy, sustainable way in its environment.

This should not surprise, given that the human genome differs only minimally from that of a roundworm.

In biomedicine, just to give you an example of what PCAST can do, we can harness the historic convergence between life sciences and physical sciences that's underway today; undertaking public projects — in the spirit of the Human Genome Project — to create data and capabilities that fuel discoveries in tens of thousands of laboratories; and identifying and overcoming scientific and bureaucratic barriers to rapidly translating scientific breakthroughs into diagnostics and therapeutics that serve patients.

The news that scientists had pieced together an early draft of the human genome had given a palpable lift to the end of the Clinton presidency.

Finally, there is even recent evidence showing that N. gonorrhoeae has incorporated a piece of human DNA into its own genome — though at this point, scientists can only speculate as to whether this gives it evolutionary advantages.