«It's important because it shows that endotoxin can't work on its own,» says Erika von Mutius of the Ludwig Maximilian University in Munich, Germany, a proponent
of the hygiene hypothesis.
Not exact matches
Allergies in general are on the rise possibly because
of what's called the
hygiene hypothesis.
It also examines various theories about the cause
of food allergies, including the «
hygiene hypothesis» (i.e., our children's environments are too sterile) and the theory that vitamin D may play a role (doctors in cold states write three to four times as many prescriptions for epinephrine than doctors in warm states).
Experts have long supported the
hygiene hypothesis as another factor bumping up our rates
of food allergies.
Changes in the prevalence
of asthma wouldn't necessarily nullify the
hygiene hypothesis, he says, but they could complicate the picture.
The study supports the «
hygiene hypothesis,» which contends that such auto - immune diseases are more common in the developed world where the prevalence
of antibiotics and antibacterials reduce children's exposure to microbes.
This 2 - decade - old idea, called the
hygiene hypothesis, suggests that lack
of exposure to dangerous parasites in childhood makes the adaptive arm
of the immune system more likely to overreact when it comes into contact with benign allergens.
Until the theory is complete, Hannaway thinks the case for the
hygiene hypothesis is strong enough to warrant mixing some messiness into the spotless world
of the modern infant.
Hannaway reckons the
hygiene hypothesis will be part
of the ultimate theory but adds, «in all likelihood there are many reasons for the emerging epidemic.»
Some researchers have proposed a «
hygiene hypothesis» that sterile surroundings deprive infants» immune systems
of proper training.
I went to a couple
of history
of science — I am very interested in history
of science — there were some great sessions on Marie Curie and on the history
of alchemy, and the
hygiene hypothesis where you find that kids who are not exposed to enough
of an immunological challenge when they are in the womb or very young can have higher rates
of asthma and autoimmune conditions; and also some stuff on the Large Hadron Collider is going to be coming up.
The
hygiene hypothesis says that a lack
of exposure to dirt and microbes is to blame for increases in allergies and asthma.
That includes revisiting the
hygiene hypothesis, which holds that a lack
of childhood exposure to microbiota and other potentially infectious agents may hinder the development
of the immune system and increase susceptibility to immunological disorders.
Researchers have been debating the «
hygiene hypothesis» for years, but it is typically discussed as an explanation for the rising incidence
of allergies and asthma in developed countries, not cancer.
The fact that the association was particularly strong in those with no siblings suggests it may be related to the «
hygiene hypothesis» — the idea that exposure to mild infections in childhood, which might be more numerous with more siblings, are important to immune system development and may reduce the risk
of immune - related diseases.
Soong is sympathetic to the
hygiene hypothesis, the idea that as we stamp out deadly diseases and sanitize our kids more than ever before, the immune system «gets kind
of lonely» and attacks harmless things.
«The early benefit
of child care exposure can potentially be explained by the
hygiene hypothesis,» said Cabana.
Consistent with the «
hygiene hypothesis,» which holds that increased microbial exposure in the first years
of life is protective for asthma, the team's findings also indicate that the presence
of house dust components that stimulate the innate immune system decreases asthma risk.
This so - called «
hygiene hypothesis» proposes that our clean lifestyle, use
of antibiotics, and a diet high in processed food has caused us to lose touch with healthy components
of our «ancestral» microbiome.
First proposed by British epidemiologist Dr David Strachan in 1989, the
hygiene hypothesis asserts that a lack
of exposure to bacteria during early childhood increases the chances
of developing allergies.
The alarming and epidemic rise
of allergy and asthma rates in the United States can be explained by one relatively simple concept (aka the
hygiene hypothesis): Our environment has become far too clean.
«The early benefit
of child care exposure can potentially be explained by the
hygiene hypothesis,» said senior study author Dr. Michael Cabana, chief
of the UCSF Division
of General Pediatrics.
«In studies
of what is called the
hygiene hypothesis, researchers are concluding that organisms like the millions
of bacteria, viruses and especially worms that enter the body along with «dirt» spur the development
of a healthy immune system.
There's a big
hygiene hypothesis that as the infections go down, you use vaccinations, you have fewer viral infections, antibiotics [inaudible 00:50:26] fewer bacterial infections, and the parasites are removed, that also in that same sequence
of time lies a dramatic uptick in the autoimmune problems.
I'll freely admit that the vaccine question is outside
of my area
of expertise, but as the
hygiene hypothesis is gaining more and more ground as one
of the contributing factors for autoimmunity, it gives me a great deal
of pause.
In fact, the
hygiene hypothesis, embraced by many scientists, purports that the reason that autoimmune diseases and atopic disorders (eczema, allergies, asthma) are epidemic in the Western world while virtually absent from developing nations is the hyper - sanitized, antibiotic - ridden society in which we live, which has decimated our gut microflora and thus obliterated their beneficial effects on our immune systems (after all, 70 %
of our immune system resides within our gut)(Vighi et al., 2008).
The media darling for an explanation is the
hygiene hypothesis — that lack
of early childhood exposure to sufficient filth improperly prepares the immune system for later battles.
This is nothing more than fear - mongering and is typical what i would expect
of those who believe in the «
hygiene hypothesis», i.e, if we keep everything sterile around us we won't get sick.
«The findings support the «
hygiene hypothesis», which suggests that being exposed to microbes as a child reduces your risk
of developing allergies,» he says.
Giardia vaccine is new, unproven, and probably based on the
hypothesis that since it exists in humans (usually due to poorly treated water supply or personal
hygiene) owners may have heard
of it and want to prevent it in their pets.