Sentences with phrase «of the major gene for»

«Ninety five percent of the aromatic rice analyzed shared the same version of the major gene for fragrance found in Thai Jasmine rice,» says Dr. Melissa Fitzgerald, grain quality researcher at IRRI.

Previously, a possibility of the existence of a major gene for hip dysplasia has been reported in the German Shepherd Dog and the Labrador Retriever (Leighton, 1997).

Not exact matches

This is the second generation of the API undertaking and will extend the study to a larger share of people who have the APOE4 gene, which is a major genetic risk factor for Alzheimer's.

Yet for decades, scientists have known surprisingly little about what genes are linked with the development of Major Depressive Disorder (MDD).

The treatment, named Kymriah, was hailed by doctors and the life sciences community as a major advance in medicine and a boon to children and young adults with a certain form of leukemia (the group for whom the gene therapy is approved).

And on Wednesday, in a major milestone for this burgeoning and potentially world - changing industry, the Dutch startup UniQure, developer of the Western world's first approved gene therapy, raised $ 82 million in its initial public offering, Reuters reports.

«Our work showed that SPIKE is indeed one of the major gene responsible for the yield increase that breeders have spent many years searching for,» said Dr. Inez Slamet - Loedin, head of IRRI's Genetic Transformation Laboratory.

A. White wheat is a different type of wheat that has no major genes for bran color (unlike traditional «red» wheat which has one to three bran color genes).

This money came from major medallion owners, including $ 4000 each from Evgeny «Gene» Freidman (who was recently in the news for his assertion that Mayor Bloomberg personally promised to «destroy [his] fucking industry» when he leaves office), Guy Roberts, and Neomi Yakuel, all of whom are on the board of the Greater New York Taxi Association, a powerful trade organization.

The major concern is that current gene drives «are probably too powerful for us to seriously consider deploying in conservation,» says geneticist Neil Gemmell of the University of Otago in Dunedin, New Zealand.

Last December, the same research team demonstrated blocking the expression of the gene that encodes apoC - III led to major relief of triglyceridemia in patients suffering a rare and extreme form of hypertriglyceridemia, which in turn opened the door for the identification of unexpected mechanisms that govern blood fat.

Since studies had shown that children in heavily polluted areas of the Central Valley had more infections, and pollution and secondhand smoke contain similar toxic compounds, Nadeau searched for genes that played a major role in fighting infection.

For example, the study found down - regulation of genes involved in interferon tau, the major signal of pregnancy recognition.

Researchers who 5 years ago successfully hunted down a gene for a common form of Alzheimer's disease (AD) announced at a press conference today that they have zeroed in on a second major Alzheimer's gene.

Finally, the authors addressed two major challenges for any study that generates large data - sets of individual genes and proteins in model organisms like yeast: How to assemble the data into coherent maps?

«However, recent work has shown that at least some of the fungal partners in arbuscular mycorrhizal symbioses lack the genes for enzymes involved in the major pathway of lipid biosynthesis, and are therefore unable to produce certain essential fatty acids,» Gutjahr explains.

To do that, they deleted the gene for SIRT1, which encodes the major mammalian sirtuin, in endothelial cells of mice.

The discovery of CHD2 as the culprit gene in a subset of children with epileptic encephalopathy is a major step for us.»

The Grants had shown that gene flow has occurred in the finches of Daphne Major during the past 40 years, but the new study found extensive evidence for gene flow throughout the roughly 1 million years that the birds have occupied the archipelago, which has helped the researchers update their understanding of how the lineages diverged over time.

Researchers from KTH Royal Institute of Technology's Science for Life Laboratory (SciLifeLab) research center and Gothenburg University employed the biological networks generated for 46 major human tissues in order to identify the liver - specific gene targets.

They looked specifically for genes coding the major histocompatibility complex (MHC)-- a molecule found on the surface of cells that acts as a crucial component of the immune systems of most vertebrates.

By developing a new technique for labeling the gene segments of influenza viruses, researchers now know more about how influenza viruses enter the cell and establish cell co-infections — a major contributing factor to potential pandemic development.

They looked for mutations in healthy tissue, and focused on 60 genes known to be a major cause of at least some forms of the disease.

Carrying a particular version of the gene for apolipoprotein E (APOE) is the major known genetic risk factor for the sporadic, late - onset form of Alzheimer's disease, but exactly how that variant confers increased risk has been controversial among researchers.

This will cover a pilot project in a small region — about 1/1000 of the human genome — containing the genes for the major histocompatibility complex (MHC), proteins that present snippets of pathogens to immune cells.

Both De Luca and Marinkovich's teams are exploring a similar gene therapy for another major form of the disease, called dystrophic EB, caused by a different genetic error affecting a larger protein.

The results open the possibility that scientists have been overlooking a major pathway for the origins of toxin genes.

Researchers had already identified two genes for the class of silk known as major ampullate, which forms the superstrong dragline threads that anchor webs and are the inspiration for a major effort to make spider silk commercially (see p. 293).

Using gene mapping and gene validation, researchers from Boston University School of Medicine (BUSM) were able to identify cytoplasmic FMR1 - interacting protein 2 (CYFIP2) as a major genetic risk factor for binge eating.

After decades of frustrations, firms believe there are now major opportunities for gene therapy in treating inherited conditions such as haemophilia.

The discovery, the product of a multiyear effort to provide a high - quality full genome map of the oil palm plant and to scour the sequence for genes of importance to both science and industry, has major implications for agriculture and the environment.

We predicted a link between gene expression evolution across species and the degree of sexual selection, but this is the first statistical evidence for it and shows how powerful sexual selection can be in leading to major changes in how a gene is expressed.»

Researchers found that the gene XIST, which is responsible for inactivating one of the two copies of the X chromosome in cells that store genetic material, works overtime in female patients with mental illnesses, such as bipolar disorder, major depression and schizophrenia.

Not only did a high percentage of embryonic cells get repaired, but also gene correction didn't induce any detectable off - target mutations and genome instability — major concerns for gene editing.

The major test compared fungal genes for telltale signs of inbreeding, where heterozygous strips of DNA become homozygous.

«Even though the specific molecular changes that are found in PCB - resistant tomcod and killifish are different, in both species AHR2 seems to be one of the genes — possibly the major gene — that is responsible for the resistance,» Hahn said.

In the new study, a team led by molecular ecologist Silke Steiger and her graduate adviser Bart Kempenaers at the Max Planck Institute for Ornithology in Starnberg, Germany, searched for smell - related genes in nine species representing seven major branches of the avian family tree.

Approximately, unbiased (AU) tests (Shimodaira 2002) were conducted for each gene to test for significant support of either the species tree (major topology) or the two minor tree topologies.

«Regarding the other histones, which are major proteins in the regulation of gene expression, we know which enzymes modify them, their functions, and how they are regulated... But for some reason, the functions of histone 1 have not been addressed,» he adds.

Several major organizations, including the American Medical Association, the March of Dimes and the American Society for Human Genetics, filed friend - of - the - court briefs in support of the challenge to the patents on the BRCA genes.

Since then he has continued to investigate new strategies to overcome the major hurdles to safe and effective gene transfer, translate then into new therapeutic strategies for genetic disease and cancer, and allowed new insights into hematopoietic stem cell function, induction of immunological tolerance and tumor angiogenesis.

This work is one basis for the use in the scientific community of transgenes as a major technique to study gene regulation in normal and malignant cells.

Oligonucleotide probe selection and synthesis — The 1,178 genes comprising the Falk Center for Molecular Therapeutics (FCMT) Rat CNS microarray were compiled from currently available NCBI / EMBL / TIGR rat sequence databases and commercially available central nervous system (CNS) microarrays (Affymetrix, Santa Clara, CA) and provided representation from greater than 90 % of the major gene ontological categories [47].

«The knowledge gained will help us understand many human disorders caused by malfunctions of gene regulation, a major goal of the NIH and of our new Institute for Genomics and Systems Biology in Chicago» White said.

The Human Protein Atlas has reached a major milestone by releasing protein data for more than 80 % of the human protein - coding genes and RNA expression data for more than 90 % of the genes.

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The alliance will employ Illumina's platform for high - multiplex single - nucleotide polymorphism (SNP) genotyping to develop tests for gene variants deCODE has previously shown to have impact on the risk of a growing number of common diseases with major public health impact.

Performance Plants is involved in gene discovery, trait development & commercialization of technologies for seeds to protect and enhance yields in all major crops globally.

ApoE4 is a major gene, with semi-dominant inheritance, for late - onset AD; however, its roles in the pathogenesis of AD are unclear.

One major change is the recommendation to test for alterations to the gene ROS1 in all cases of lung adenocarcinoma, which make up about half of all cases of non-small cell lung cancer.