Sentences with phrase «of the new blood vessels in»

Last spring the team reported that their fibers induced the formation of new blood vessels in both cell cultures and living animals.
«We saw the formation of new blood vessels in tumors reduced by 70 percent,» she says.
«This novel combination therapy simultaneously targets multiple pathways contributing to metastasis» explains Professor Augustin, «On the one hand, we inhibit the growth of new blood vessels in metastases.
«If we could prevent development of the new blood vessels in the cancer tissue driven by these signals, tumor growth and metastasis can be slowed down or prevented.»
Earlier studies by Basu and others have shown that dopamine blocks the growth of new blood vessels in tumors by inhibiting the action of vascular endothelial growth factor - A (VEGF - A).
Cardiac cell therapy stimulate the growth of new blood vessels in the heart to help restore blood flow to your heart.
Other research has shown that oxygen - deprived cells in the retina produce a type of protein called vascular endothelial growth factor (VEGF), which triggers the growth of new blood vessels in the retina.
Recent studies have shown that curcumin can reduce growth of new blood vessels in tumors and metastasis and basically help kill off cancerous cells.
Exercise manages insulin levels, reduces inflammation, and helps stimulate the growth of new blood vessels in the brain.
Inhibit angiogenesis, which prevents the growth of new blood vessels in breast cancer cells.
A component of green tea called epigallocatechin gallate (ECCG) is a powerful antioxidant that is believed to suppress the growth of new blood vessels in tumors.
Therapeutic benefits of HBOT include a greatly increased oxygen concentration in all body tissues (even with reduced blood flow), improved healing time of stubborn wounds, stimulated growth of new blood vessels in areas of reduced circulation.
This type of chemotherapy schedule was developed with the goal to block the formation of new blood vessels in the cancer, i.e. to have an «anti-angiogenic» effect.

Not exact matches

One of the hallmarks of rheumatoid arthritis is the development of new blood vessels, or angiogenesis, in the joints.
However its current use as a treatment to block new blood vessel growth in the wet form of age - related macular degeneration means there is already a body of research from which we can perhaps draw useful insights.
That's because hospitals are equipped with powerful new scanning machines primarily used to identify tumors, ballooning blood vessels, bone fractures, and a wide range of disorders in people.
HIF - 1 senses reduced oxygen levels and triggers many changes in cellular function, including a changed metabolism and sending signals for the formation of new blood vessels.
«In addition to protecting the islets, our engineered material promotes the formation of new blood vessels to nourish the cells.»
This happens because the loss of blood flow in a vessel causes the local oxygen level to drop, which stimulates local production of vascular endothelial growth factor, or VEGF, a protein which in most tissues causes the growth of new blood vessels to repair damage.
New research published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that age (or age at diagnosis) and duration of diabetes disease are linked to the risk of death and marcovascular complications (those in larger blood vessels), whereas only diabetes duration is linked to the risk of microvascular complications (in smaller blood vessels such as those in the eyes).
Some heart disease patients may not be able to grow new blood vessels around blocked arteries because they can't make enough of a vital protein, according to a report in the latest issue of Circulation.
Researchers in the Rice lab of chemist and bioengineer Jeffrey Hartgerink had just such an experience with the hydrogels they developed as a synthetic scaffold to deliver drugs and encourage the growth of cells and blood vessels for new tissue.
In mice, exercise generally stimulates growth of new blood vessels and boosts muscle mass.
A new report in The American Journal of Medicine found that a glass or two of red wine before lighting up a cigarette can counteract some of the short - term negative effects of smoking on blood vessels.
The international research team behind the study now suggests that targeting inflammation and fibrosis in the small blood vessels of the pancreatic islets may offer a new way of treatment for age - dependent dysregulation of blood glucose levels.
Trebananib (formally known as AMG 386; Amgen) is a first - in - class peptide - Fc fusion protein (or peptibody) that targets angiogenesis (the growth of new blood vessels into cancerous tumors) by inhibiting the binding of both angiopoietin 1 and 2 to the Tie2 receptor.
Milton Schiffenbauer of Pace University in New York, US, says that by protecting against this damage, polyphenols may reduce the blood vessel inflammation thought to promote cardiovascular disease.
In another study of mice injected with GDF11, postdoc Lida Katsimpardi and others in the lab of Harvard neuroscientist Lee Rubin found that GDF11 also encourages growth of new blood vessels and olfactory neurons in the mouse braiIn another study of mice injected with GDF11, postdoc Lida Katsimpardi and others in the lab of Harvard neuroscientist Lee Rubin found that GDF11 also encourages growth of new blood vessels and olfactory neurons in the mouse braiin the lab of Harvard neuroscientist Lee Rubin found that GDF11 also encourages growth of new blood vessels and olfactory neurons in the mouse braiin the mouse brain.
• A Columbia University team headed by Silviu Itescu used human bone marrow to build new blood vessels in the hearts of rats.
Later, it helps in the formation of new blood vessels and cell growth, and at the final phase, reduces scarring.
If fertilized, the egg grows in place, supporting itself via placental tissues that eat into the wall of the tube and by releasing chemicals that stimulate the formation of new blood vessels.
An international team of researchers, including scientists at A * STAR's Institute of Medical Biology (IMB), has shed new light on how the circulatory system and blood vessels are formed in the embryo.
Green's laboratory, which specializes in designing new drug - delivery systems, worked with Campochiaro and Aleksander Popel, Ph.D., professor of biomedical engineering, whose laboratory discovered the new drug — a short piece of protein that blocks the growth of unwanted blood vessels.
«The discovery of ferroelectricity in blood vessel walls adds an important dimension to the biophysical properties of blood vessel wall, which could lead to the development of new methods in prevention and treatment of cardiovascular diseases,» Liu and collaborators write.
Richard Lipton, director of the Montefiore Headache Center in New York City, says triptans were developed in response to the older idea that the dilation of blood vessels is the primary cause of migraine; triptans were supposed to inhibit it.
When the team tested the drug on cells grown in the lab, they found that it killed blood vessel cells and prevented growth of new blood vessels.
The toxicity of chokeberry extract on normal blood vessel lining cells was tested and found to have no effects up to the highest levels used (50 ug / ml), suggesting that the cell death effect is happening in a way other than through preventing new blood vessel formation (anti-angiogenesis), a process that is important in cancer cell growth.
Compared to their unmodified counterparts, the growth factors containing the PIGF - 2 sequence resulted in much faster wound closing and production of granulation tissue, and also led to a more pronounced new blood vessel formation, which is essential in sustaining the latter.
Two teams of Harvard bioengineers made big strides toward that goal in 2014, reporting two new 3 - D - printing methods that help construct rudimentary blood vessels.
In a series of studies this year, molecular geneticists at the University of Pittsburgh School of Medicine used a harmless virus to ferry new genes through the bloodstream, across blood vessel walls, and into almost every muscle cell in the bodies of hamsters bred to have human genetic diseaseIn a series of studies this year, molecular geneticists at the University of Pittsburgh School of Medicine used a harmless virus to ferry new genes through the bloodstream, across blood vessel walls, and into almost every muscle cell in the bodies of hamsters bred to have human genetic diseasein the bodies of hamsters bred to have human genetic diseases.
Cell migration is highly coordinated and occurs in processes such as embryonic development, wound healing, the formation of new blood vessels, and tumour cell invasion.
The research conducted by the University of Sheffield, published today in the Journal of Neurourology and Urodynamics, provides evidence which supports the use of a softer and more elastic material better suited for use in the pelvic floor and one that releases oestrogen into the surrounding pelvic tissue to form new blood vessels and ultimately speed up the healing process.
Roughly 20 percent of patients with age - related macular degeneration suffer from abnormal blood vessel growth and vascular leakage, says Campochiaro, and so may be helped by this new therapy, if it proves to work in clinical trials.
In their paper published online in the Journal of the National Cancer Institute, an MGH research team reports finding that the growth of metastases in lymph nodes — the most common site of cancer spread — does not require new blood vessels but instead takes advantage of existing blood vesselIn their paper published online in the Journal of the National Cancer Institute, an MGH research team reports finding that the growth of metastases in lymph nodes — the most common site of cancer spread — does not require new blood vessels but instead takes advantage of existing blood vesselin the Journal of the National Cancer Institute, an MGH research team reports finding that the growth of metastases in lymph nodes — the most common site of cancer spread — does not require new blood vessels but instead takes advantage of existing blood vesselin lymph nodes — the most common site of cancer spread — does not require new blood vessels but instead takes advantage of existing blood vessels.
Working with mice, a multicenter team of researchers has found a new way to reduce the abnormal blood vessel growth and leakage in the eye that accompany some eye diseases.
In fact, although only 10 percent of patients develop new blood vessels, this complication is responsible for most of the legal blindness associated with macular degeneration.
Unfortunately, the retina is such a complex and highly ordered tissue that the in - growth of these new blood vessels causes more visual loss than the original degenerative process.
One surprising finding from the study co-led by Johns Hopkins, Ehret says, was that many of the new sites identified were near genes that are active in cells that line the inside of blood vessels, suggesting those cells are somehow involved directly in blood pressure control.
Due to the lack of oxygen in the cancer cells, VEGF - A (Vascular Endothelial Growth Factor) is formed and this promotes the formation of new blood vessels to supply the tumor.
The cells were cultured in a suitable medium and the researchers checked the molecules they produced, in particular the pro-angiogenic ones, that is, molecules that nurture the production of new blood vessels.
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