Sentences with phrase «of the potassium ion»

The visual neurons, which had fired abnormally during the cortical spreading depression, had released large amounts of potassium ions.

That's because sequential rings of oxygen atoms exactly match the size, and balance the charge, of potassium ions.

This allows for a larger flow of potassium ions that are leaving the neuron,» the authors note.

The researchers who have conducted the study have previously discovered that naturally occurring resin acids can regulate an ion channel that allows the passage of potassium ions.

«We think that cAMP in fact widens the filter somewhat, thereby controlling the flow of potassium ions.»

Neurons transmit information with the help of special channels that allow the passage of potassium ions.

They form a pore with a filter that selectively allows the passage of potassium ions, and which is controlled by the signaling molecule cAMP.

Not exact matches

Minerals: Coconut flour is a source of electrolytes because it is rich in ions such as manganese, calcium, selenium, phosphorus and potassium.

This is a natural mineral (salts of potassium and phosphate ions) present in food and supplements that also serves to stabilize products.

Human milk has lower levels of protein, calcium, sodium, potassium and other ions.

Bound to the cell membrane, Na ± K+ATP ase uses the energy of adenosine triphosphate (ATP) molecules to pump sodium out of the cell and potassium into the cell, maintaining a charge gradient that allows ions to flow through open channels.

In frogs with the disease, the skin's ability to take up sodium and potassium ions from the water decreases by more than 50 per cent, Jamie Voyles of James Cook University in Townsville, Queensland, Australia, and his colleagues found (Science, DOI: 10.1126 / science.1176765).

But the native language of biology is positive: its building blocks are protons and positively charged ions such as potassium, sodium and calcium.

BK channels are potassium ion channels found on the surface of a variety of cell types that are essential for the regulation of several key physiological processes, including smooth muscle tone and neuronal excitability.

The potassium ion channel is critical to ending each heart contraction and is made up of the proteins Q1 and E1.

Although any kind of ion can enter the long hollow stem — the pore of the channel — only potassium ions can pass through a filter near the pore's end.

The mutation resulted in a lower single channel conductance for calcium and a strongly increased conductance for sodium and potassium, indicating that glutamic acid - 95 is a crucial constituent of the ion selectivity filter.

This small protein molecule contains a loop which fits, like a key in a lock, into the ion channel proteins found on nerve cell membranes, which are used to transport sodium and potassium ions in and out of the cell.

The ion channels closed and the flow of potassium stopped.

For example, ATP1B1 encodes a sub-unit of the sodium - potassium plasma membrane pump, which is essential for water and ion transport.

Despite a large body of work, the exact molecular details underlying ion selectivity and transport of the potassium channel remain unclear.

The cell's most ubiquitous gateways are potassium ion channels — the importance of this type of ion channels was underpinned in 2003 when Roderick MacKinnon received the Nobel Prize in Chemistry for resolving the first atomic structure of the bacterial KcsA potassium channel.

The mechanism is produced by layers of electrically charged particles (ions of sodium and potassium) on either side of the nerve membrane that change places when stimulated.

The researchers have investigated the effect of the substances on a potassium ion channel from fruit flies.

On the basis of this selective permeability, ion channels are classified as potassium channels, sodium channels, etc..

«These effects happen at the minute level of potassium, chloride, and other ions moving across the neuron outer membrane via channels and transporters,» Dani said.

His hydrogen - ion - creating system uses an indium tin oxide electrode and a container of water with cobalt and potassium phosphate mixed in.

Action potential When about 0.1 volt kicks in (1/100, 000 the strength of a static shock from a rug), negatively charged potassium rushes out of the cell, and positively charged sodium floods in at 100,000,000 ions per second.

They found that when the potassium channel is open, water molecules quickly bind to tiny cavities within the protein structure, where they block the channel in a state that prevents the passage of ions.

Voltage - dependent potassium ion (K +) channels (Kv channels) conduct K + ions across the cell membrane in response to changes in the membrane voltage, thereby regulating neuronal excitability by modulating the shape and frequency of action potentials.

Nerve cells use the movement of positively charged sodium and potassium ions across a membrane to create a chemical gradient that drives neural signals.

Nerve cells use the movement of positively charged sodium and potassium ions across a membrane to create an electrochemical gradient that drives neural signals.

Functional characterization of inward rectifier potassium ion channel in murine fetal ventricular cardiomyocytes.

We want to understand how cellular physiology is controled by basic molecular and cellular pathways regulating the biology of potassium - selective ion channels.

July 29, 2013 Water molecules control inactivation and recovery of potassium channels Just 12 molecules of water cause the long post-activation recovery period required by potassium ion channels before they can function again.

Another gem in the Jans» trove of findings emerged from their efforts to isolate the gene for proteins that shuttle potassium ions in and out of cells.

Unlike the recent bout of exploding lithium - ion cell phone batteries, the steel - brass batteries use non-flammable water electrolytes that contain potassium hydroxide, an inexpensive salt used in laundry detergent.

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transportion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transportIon channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

It's also an excellent source of vitamin C, ion, calcium, potassium, magnesium, and dietary fiber.

Excessive urination also leads to a loss of ions, such as sodium, potassium and magnesium etc. which are required by the body cells to perform properly.

† It helps maintain normal function of the heart, muscles, and nerves by facilitating the transport of ions like potassium and calcium across cell membranes.

The Na / K pump operates by transporting two potassium ions into your cells while moving three sodium ions out of your cells.

Potassium is a mineral and ion, one of the body's electrolytes, which maintain fluid balance in the cells.

The kidneys regulate the concentration of ions such as sodium, potassium, phosphate and hydrogen.

Considering Potassium Bicarbonate is metabolically similar to Potassium Gluconate, ie: Potassium Gluconate provides Potassium Ions (K + electrolytes) and the Gluconate metabolises in the liver to create Bicarbonates (HCO3 − electrolytes), therefore we have now changed the type of Potassium booster in PrimalKind Version 1.2 to Potassium Bicarbonate.

One of the main functions of the kidneys is to regulate both the volume and the composition of body fluid, including electrolytes, such as sodium, potassium, and chloride ions.

The details are complicated, but basically, in an intense workout, potassium ions accumulate outside of working muscles, making it harder for sodium ions to propagate the electrical signal.

The rationale is simple: Increases in potassium ion concentration stimulate the secretion of insulin (Desirable in terms of treatment objectives).

Magnesium also plays a role in the active transport of calcium and potassium ions across cell membranes, a process that is important to nerve impulse conduction, muscle contraction, and normal heart rhythm [3].

Tiny ions of hydrogen, chloride, sodium, potassium, magnesium, and calcium keep the brain, heart, and muscles functioning.