Sentences with phrase «of therapeutic approaches with»
EMDR is a complex method of psychotherapy that integrates a range of therapeutic approaches with eye movements or other forms of rhythmical stimulation that jump - start the brain's information processing system.
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If AA could combine its amazing program of social therapy with psycho therapeutic insights and techniques, particularly group therapy, an approach to alcoholism with maximum effectiveness might be produced.
A variety of therapeutic approaches — from Ludwig Binswanger's psychoanalytic approach to Viktor Frankl's neo-Adlerian methodology — have been associated with the existentialist position in philosophy.
The difficulty that stems from just assembling therapeutic components from different sources is that this approach usually produces a kind of hash eclecticism — a theory from here, a technique from there — with no integrating structure, no internally consistent core of assumptions about the nature, process, and goals of therapeutic change.
«At the same time, as the human ZNF217 is associated with poor survival in a variety of cancers, understanding how this protein operates in physiological conditions may help to predict cancer risk, achieve earlier diagnosis and provide novel therapeutic approaches.»
This imaging approach could also, in the future, help better define which patients with autoimmunity will likely progress to diabetes and classify subgroups of patients who might benefit from different therapeutic strategies.
«But if we can use those treatments in combination with a method of enhancing the brain's immune system, we would have a two - pronged approach that has tremendous therapeutic potential.»
Therefore, a novel therapeutic approach in inflammatory breast cancer could involve a combination of conventional chemotherapy with small - molecule inhibitors of the Cdk2 cell cycle kinase.
«Moreover, our initial data suggest that subtypes of AML with a poor prognosis are likely to be sensitive to this new therapeutic approach,» she says, adding that less than 10 percent of patients with certain forms of AML achieve long - term survival.
But in the future, this new line of research may offer a therapeutic approach for kids with Prader - Willi, Langouet says.
The continuation of this line of research is opening new avenues to identify what specific signals are used to promote this increased neurogenic response, with views focused in targeting neurogenesis as a therapeutic approach to promote the regeneration of lost neurons.»
«This therapeutic approach offers new hope for people whose migraines can not be treated with existing medicine,» says Stephen D. Silberstein, M.D., principal investigator of the HALO CM trial, Professor of Neurology and Director of the Jefferson Headache Center at the Jack & Vicki Farber Institute for Neuroscience at Thomas Jefferson University Hospital.
Inhibiting ALDH1A3 - mediated pathways slows the growth of mesenchymal glioma stem cells and might provide a promising therapeutic approach for glioblastomas with a mesenchymal signature.
Practically, these findings will enrich therapeutic approaches and certain motor strategies that will improve the quality of life of people with TS.
Dr. Paul R. Sanberg, Distinguished University Professor, a co-author of the paper, concluded that «these novel data showing BSCB damage in subacute and chronic ischemic stroke may lead to development of new therapeutic approaches for patients with ischemic cerebral infarction.»
«Our research shows that targeting cannabinoid receptors in the periphery with pharmacological inhibitors that do not reach the brain holds promise as a safe therapeutic approach for the treatment of overeating and diet - induced obesity,» said Nicholas V. DiPatrizio, an assistant professor of biomedical sciences in the School of Medicine, who led the research project.
«We have found another piece in the cancer puzzle — knowledge that could one day be used for more precision in screening and breast cancer prevention, and also help with therapeutic approaches to block some of the earliest alterations before cancer develops and starts to spread.»
A new therapeutic approach tested by a team from Maisonneuve - Rosemont Hospital (CIUSSS - EST, Montreal) and the University of Montreal gives promising results for the treatment of multiple myeloma, a cancer of the bone marrow currently considered incurable with conventional chemotherapy and for which the average life expectancy is about 6 or 7 years.
«Of course, one must be cautious with such an approach, but the ability to use combinations of treatments including antibiotics plus immune modulators such as these NFAT inhibitors might have considerable therapeutic value.&raquOf course, one must be cautious with such an approach, but the ability to use combinations of treatments including antibiotics plus immune modulators such as these NFAT inhibitors might have considerable therapeutic value.»f treatments including antibiotics plus immune modulators such as these NFAT inhibitors might have considerable therapeutic value.»
To achieve gene editing in mice with thalassemia, professor of therapeutic radiology and of genetics Peter M. Glazer, M.D. and his co-authors developed an alternative approach using a novel combination of nanoparticles, synthetic pieces of DNA, and a simple IV injection.
His primary clinical and research focus is dementia, with specific areas of interest including biomarkers to assist in the diagnosis and understanding of disease mechanisms for Alzheimer's and Parkinson's disease, and translational research using novel therapeutic approaches.
As a further therapeutic option, the researchers are pursuing the approach of using specifically developed antibodies against CEACAMs in order to fight diseases associated with the bacterium.
The study, published September 7 in Nature Medicine, provides promise for a new therapeutic approach to treating the millions of people suffering from muscle diseases, including those with muscular dystrophies and muscle wasting associated with cancer and aging.
«Evidence - based therapeutic approaches are vital to help all children deal with the effects of sexual abuse.
«At present, there is no clinically approved glucose - responsive modified insulin,» says Matthew Weber, Ph.D., co-first author with Chou and Benjamin Tang, Ph.D., who performed the work together while postdoctoral fellows at MIT in collaboration with senior authors and MIT professors Robert Langer, Ph.D., and Daniel Anderson, Ph.D. «The development of such an approach could contribute to greater therapeutic autonomy for diabetic patients.»
Interestingly, genomic analyses suggested that ESCC and head and neck squamous cell carcinoma (HNSCC) shared some common pathogenic mechanisms, and ESCC development is associated with alcohol drinking.These findings would provide a brand - new insight into the understandings of ESCC tumorigenesis, and would help clinicians to develop more effective diagnostic and therapeutic approaches for ESCC.
The designation recognizes the Center's collaborative environment and expertise in harnessing translational research to bridge scientific discovery to clinical delivery, with the ultimate goal of successfully introducing novel diagnostic, therapeutic and preventive approaches to cancer.
We leverage our cutting - edge platforms to produce product candidates and utilize distinct therapeutic approaches that, we believe, address the shortcomings of existing therapies and have the potential to treat a broad patient population either as individual therapies or in combination with other mechanisms of action.
Dr. Kulkarni's research focuses on investigating signaling pathways impacting growth and function of pancreatic islet cells with the long - term goal of improving therapeutic approaches for the treatment of type 1 and type 2 diabetes and obesity - associated conditions.
«The collaboration is important for Biotecnol's strategy of working with top cancer institutions in the immune - oncology field which will accelerate the development of cutting - edge therapeutic approaches to fight cancer.»
Our objective is to use our microbiome therapeutic approach to improve the efficacy of immunotherapy in patients with life - threatening cancers.»
The call seeks to address the need for innovative research to underpin new approaches to therapeutic intervention, connect centres with a critical mass of resources and expertise to drive a step change in neurodegeneration research.
The resulting data are being combined in a systems biology approach with high - resolution clinical phenotyping and findings obtained with a large array of established and novel in vitro, ex vivo and in vivo disease models to identify disease - associated genetic variants, disease - defining molecular signatures, and potential targets for therapeutic intervention.
«Nevertheless, this is a potentially exciting finding and it is possible that nivolumab, most likely in combination with other approaches such as therapeutic vaccines, may have a role in the eventual discovery of a cure for HIV.»
These promised to provide a new therapeutic target for treating obesity, with the researchers finding that they share the fat - burning abilities of brown cells, though they do decrease in number as we approach middle age.
Our group is specifically working on improvement of islet isolation and transplantation protocols in clinical practice and the development of novel therapeutic options in the field of beta cell replacement with a clear translational «bench to bedside» approach by linking experimental research with preclinical and clinical work:
«This partnership puts our mRNA Therapeutics platform in the hands of Karolinska's world - class scientists and clinical researchers to develop new drugs and therapeutic approaches that can not be done with small molecules or biologics — bringing new hope to patients with serious diseases.»
The project has the potential to provide important new information about mechanisms of drug resistance in melanoma - a key medical problem - as well as to evaluate the potential of splicing inhibitors as a therapeutic approach in two groups of melanoma pts with different response kinetics.
Our group has 3 major goals: Develop novel therapeutic approaches based on centrosomal clustering To further develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to clinical trials To evaluate novel agents in the preclinical setting and to initiate early phase clinical trials in hematologic malignancies with focus on multiple myeloma
«This therapeutic approach offers new hope for people whose migraines can not be treated with existing medicine,» says Stephen D. Silberstein, M.D., principal investigator of the HALO CM trial, Professor of Neurology and Director of the Jefferson Headache Center at the Vicki & Jack Farber Institute for Neuroscience at Thomas Jefferson University Hospital.
The objectives to achieve within the 4 years of the NAREB project are: 1 / to select antibacterial molecules and design nanocarriers with strong antibacterial activity, 2 / to test in vitro and in vivo the best therapeutic combinations including innovative genomic and bioimaging approaches, 3 / to assess safety, regulatory and production (GLP / GMP) aspects for the most promising nanoformulations, and 4 / to establishing the Clinical Development Plan for the preparatory work for the subsequent clinical testing of the selected nanoformulations.
The goal of her laboratory is to combine high - resolution computational reconstructions of the microbiome with synthetic biology to devise innovative approaches to create novel therapeutic interventions and investigate the underlying ecology of skin microbial communities.
This department provides clinicians and researchers with human and technological resources enabling the development of application - oriented projects, with the objective of improving care for cancer patients (assessment and validation of diagnostic, prognostic and patient support tools, as well as development of biomedical devices or therapeutic approaches resulting from basic research).
The Zhang laboratory studies ovarian cancer biology with the goal of developing novel therapeutic approaches to combat the disease with precision.
Together with our collaborators in other UT Health San Antonio departments, we are currently investigating if prohibiting the accumulation of DNA abnormalities can be used as a novel therapeutic approach for treating MDS.
The ultimate goal of this work is to contribute to the design of effective therapeutic approaches that target dysregulated ER functions for patients with leukemia and other malignancies.
With multiple therapeutic approaches now either in early clinical trials or nearing human testing, optimism is starting to mount that one of these approaches will ultimately prove a success.
Despite the marginal improvements in survival of patients suffering from malignant glioma treated with gene therapy vectors, the clinical trials conducted so far using viral vectors, in particular adenoviral vectors, have proven that the use of adenoviral vectors is a safe therapeutic approach, even in large, multicenter, phase 3 clinical trials.
Together with the region - specific progression of plaque densities, these models present a valuable tool for early intervention and improved assessment of potential therapeutic approaches for AD and in particular AD - induced aggression.
Detection of immune cell checkpoint and functional markers in the lung TME: The field of cancer immunotherapy continues to expand rapidly over recent years, with promising clinical results by immune checkpoint inhibitors and other therapeutic approaches.