Through the CIC program, the Cancer Research Institute conducts a number of important initiatives that seek among other things to build consensus across the field on key issues, to develop and implement new standards for carrying out and reporting immunological monitoring assays
of therapeutic cancer vaccines, and to establish and promote the adoption of new criteria for evaluating the clinical impact of cancer immunotherapies.
Celis» lab has shown how poly - IC, which behaves like the genetic material of viruses to also get the attention of the immune system, can improve the effectiveness
of therapeutic cancer vaccines.
Not exact matches
On the morning
of Monday, October 3, the Nobel Committee announced that immunologist Ralph Steinman had won the Nobel Prize in Medicine for his work on immune cells and a discovery that led to the first
therapeutic cancer vaccine.
One
of the most contentious and closely scrutinized decisions before the FDA concerns Provenge, a proposed
therapeutic vaccine made by Dendreon for use against prostate
cancer.
Unlike preventive vaccinations,
therapeutic cancer vaccines of this type are meant to kill established
cancer cells.
Currently there are only a few approved
therapeutic cancer vaccines, none
of which are approved for the treatment
of GBM.
A new
therapeutic vaccine, GTL001, developed by Genticel to clear HPV strains 16 and 18 — the types most likely to cause
cancer — is being evaluated for safety in a Phase I clinical trial at the University
of Louisville.
The second focus on my research is the development
of novel
therapeutic vaccine approaches for
cancer.
Drew Pardoll, Glenn Dranoff, Elizabeth Jaffee, Hyam Levitsky, and colleagues conduct preclinical studies showing that a
vaccine composed
of tumor cells irradiated and genetically modified to produce immune system growth factor GM - CSF (granulocyte - macrophage colony - stimulating factor)-- which would become known as the
therapeutic cancer vaccine GVAX — could induce potent, specific, and long - lasting anti-tumor immunity in multiple mouse tumor models.
The trial was part
of the
Cancer Vaccine Collaborative, a joint program between the Cancer Research Institute and the Ludwig Institute for Cancer Research to develop therapeutic cancer vac
Cancer Vaccine Collaborative, a joint program between the
Cancer Research Institute and the Ludwig Institute for Cancer Research to develop therapeutic cancer vac
Cancer Research Institute and the Ludwig Institute for
Cancer Research to develop therapeutic cancer vac
Cancer Research to develop
therapeutic cancer vac
cancer vaccines.
Lizée and colleagues are developing a different type
of vaccine called a
therapeutic vaccine, which triggers an attack against established
cancer.
This includes utilizing a modified chimpanzee virus as a
vaccine carrier to induce an immune response against HIV, and a new
therapeutic vaccine against human papillomavirus (HPV), a leading cause
of cervical
cancer.
A fact sheet that provides an overview
of how the immune system functions and describes the actions
of biological therapies, such as monoclonal antibodies, cytokines,
therapeutic vaccines, the bacterium bacillus Calmet - Guérin,
cancer - killing viruses, gene therapy, and adoptive T - cell transfer.
We have validated the glycosphingolipid - binding non-toxic B - subunit
of Shiga toxin as a delivery tool for
cancer immunotherapy, and are currently building
therapeutic vaccine prototypes for breast and head - and - neck
cancers.
Turnstone's
therapeutic platform is a first - in - class, tumor - targeted oncolytic
vaccine that combines potent tumor - killing effects
of oncolytic viruses with the benefits
of a
cancer vaccine that harnesses the patient's own immune system to fight disease in a sustainable manner.
Most recently, CRI has launched a new «venture philanthropy» program called the
Cancer Vaccine Acceleration Fund (CVAF) as a means to catalyze development of next - generation therapeutic cancer vaccines and other immunotherapies by helping to address the critical shortage of capital available for early stage clinical t
Cancer Vaccine Acceleration Fund (CVAF) as a means to catalyze development
of next - generation
therapeutic cancer vaccines and other immunotherapies by helping to address the critical shortage of capital available for early stage clinical t
cancer vaccines and other immunotherapies by helping to address the critical shortage
of capital available for early stage clinical trials.
NEW YORK, NY — April 30, 2010 — The
Cancer Research Institute celebrates yesterday's announcement of the first therapeutic cancer vaccine to receive approval from the U.S. Food and Drug Administr
Cancer Research Institute celebrates yesterday's announcement
of the first
therapeutic cancer vaccine to receive approval from the U.S. Food and Drug Administr
cancer vaccine to receive approval from the U.S. Food and Drug Administration.
«Based on the clinical evidence we've gathered over the past decade in our
cancer vaccine trials,» Old said, «and in light
of data from a variety
of trials by others within the field, we believe
therapeutic cancer vaccines will increasingly emerge as one
of the safest and most powerful ways to combat a variety
of cancers.»
Physicians with the Personalized Medicine Program at The Tisch
Cancer Institute have initiated a phase I proof -
of - concept study, a fully personalized multipeptide
therapeutic vaccine designed to target tumor - derived neoantigens for individual patients.
The Focus: Deep dive into hot topics
of therapeutic nutrition, biased research, the
vaccine debate, and integrative
cancer treatments.
It is focused on the development
of preventive and
therapeutic vaccine products and
cancer drugs for patients with unmet medical needs.