Sentences with phrase «of therapeutic development»
We are concerned that a public outcry about such an ethical breach could hinder a promising area of therapeutic development,» write Lanphier and his colleagues, who include Fyodor Urnov, a pioneer in gene - editing techniques and scientist at Sangamo BioSciences in Richmond, California.
https://www.scientificamerican.com/ Not exact matches
Jennifer has more than 20 years of regulatory experience, integrating regulatory strategy into drug development and precision medicine across multiple therapeutic areas.
Forward - Looking Statements This press release contains forward - looking statements, including, without limitation, statements relating to: the continued build - out of Alder's executive team; Alder's growth and development; the role of Alder's Chief Operating Officer; the continued development and clinical, therapeutic and commercial potential of eptinezumab; the opportunity of eptinezumab to transform treatment for migraine patients; and the anticipated commercialization of eptinezumab.
Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.
Alnylam Pharmaceuticals stock plummeted 45 percent after the therapeutics company announced it was discontinuing its development of revusiran, a therapeutic aimed at treating hereditary ATTR amyloidosis.
«It essentially gives us a periodic table,» Ron DePinho, President of MD Anderson Cancer Center says, which has provided us with both diagnostic and therapeutic value as well as helped us design clinical trials to accelerate the development of new cancer drugs,».
IONIS» FORWARD - LOOKING STATEMENT This press release includes forward - looking statements regarding Ionis Pharmaceuticals» business and the therapeutic and commercial potential of Ionis» technologies and products in development, including SPINRAZA, inotersen and volanesorsen.
Amarin's product development program leverages its extensive experience in lipid science and the potential therapeutic benefits of polyunsaturated fatty acids.
Mannkind, which focuses on the development and commercialization of inhaled therapeutic products for patients with diseases such as diabetes and pulmonary arterial hypertension, entered a shallow but persistent downtrend in 2004, posting a series of lower highs into 2015.
The curriculum should be evaluated and revised in terms of its effectiveness in preparing the students to become facilitators of growth and healing, and of the development of therapeutic - redemptive communities in the churches.
This makes possible the fuller development of new theories informed at once by Whitehead's cosmology and by immersion in therapeutic practice.
Self - help groups (many of which are modeled on Alcoholics Anonymous) represent one of the most hopeful developments in the whole field of contemporary therapeutic groups.
One of the serendipities modern readers find in studying Gregory is that he seems to anticipate several psychological approaches and therapeutic developments that are currently considered to be wholly unprecedented innovations of contemporary psychotherapy.
Hall characterizes this turn in various ways: as a shift in emphasis from «external technologies» to «internal technologies aimed at self - creativity» (UP 395; cf. 318 - 47), as the development of a «therapeutic society containing a plurality of techniques and practical reason in an aesthetic methodology» (UP 242).
But the last biting incident he had at school set into motion a chain of events that led us to a great child development specialist, who sent us to a kick - ass occupational therapist and also helped us find a therapeutic aide for him in the classroom.
Through regular home visits and the development of a strong therapeutic relationship between nurse and mother, the programme has three main aims:
Pediatric occupational therapists can also use their unique understanding of child development to educate others on the therapeutic qualities of nature.
Our stockings provide therapeutic care for your feet, while preventing the development of serious vascular conditions.
Chris Sekely CWS Kindergarten teacher since 1996 Penn State University, BS in Human Development University of Pittsburgh, MS in Public Health Antioch College, MEd Waldorf Certification & Gradalis Therapeutic Certification Returning Board Member in 2016 Connie Davis CWS Class teacher since 2003 University of the South, BA English Literature 1985 Manufacturing Management 1986 - 1998 Antioch University, Waldorf Teacher Certification 2008 CWS Faculty Chair 2007 CWS Grades Chair 2012 CWS College Chair 2017 Returning Board Member 2017
These toys aim to respond to your child's sensory processing challenges, and are sure to be not only a source of fun, but also a tool that is therapeutic and which helps with his or her development.
Vocabulary development, rehearsal, and practice of using language in social situations are often helpful therapeutic methods.
Therapeutic interventions are child - led and child - oriented in nature as well as take account of a child's holistic development and well - being.
Athletic Trainers work closely with physicians and other health professionals and are responsible for being current in several areas, including: an evidence based practice (EBP), prevention and health promotion (PHP), clinical examination and diagnosis (CE), acute care of injuries and illnesses (AC), therapeutic interventions (TI), psychosocial strategies and referral (PS), healthcare administration (HA), and professional development and responsibility (PD).
We offer a number of therapeutic services for children from one year of age through adolescence that include individualized speech and language therapy, parent training to facilitate language development in children who are late talkers or stuttering, and interventions to facilitate social communication and pragmatics.
Thus, although improving the economic status of families promotes more positive outcomes for children's cognitive development and academic achievement, direct services and therapeutic interventions may be a comparatively more promising alternative for improving children's psychosocial development and reducing behaviour problems.
In addition, risks associated with the usability, therapeutic efficacy and market share of medicinal substances are usually realized only in the final stages of drug development.
Of approximately 300 staff at the Center for Therapeutic Research, only nine postdocs and students are conducting basic research; the rest work in drug discovery and development.
For decades there has been some belief that pregnancy has an adverse effect on the course of melanoma, increasing the risk of its development, ability to spread throughout the body, and recurrence, said study coauthor Mark Faries, MD, FACS, who was director of therapeutic immunology at the John Wayne Cancer Institute, Santa Monica, Calif. at the time the study was conducted.
Richard Hargreaves, executive director of imaging at Merck Research Laboratories, says, «Nuclear imaging using radiotracers gives the opportunity to put your arms around proof - of - concept very early in a drug discovery and development program by focusing the selection of doses to study on those proven to deliver enough drug to the target therapeutic sites.»
«Knowing the genetic basis for these types of problem will permit development of diagnostic tests and ultimately therapeutic interventions,» says co-author Laurent Fasano, also from CNRS.
«The basic research nature of my work made it possible to publish without infringing on any other work, such as the development of [therapeutic] molecules.»
«This work represents a mechanistic insight that could lead to the development of a new therapeutic approach for preventing asthma.»
This approach is routinely utilized at USAMRIID to study the development of viral therapeutic resistance against antiviral countermeasures, according to Dr. Gustavo Palacios, director of the center and senior author of the study.
These newly discovered molecular targets will allow the development of therapeutic strategies that may be explored as possible routes to eliminate leukemic cells» resistance to chemotherapy.
This study is among several funded under a public - private partnership established in 2008 between NICHD and the WALTHAM Centre for Pet Nutrition, a division of Mars Inc., to establish a human - animal interaction research program to support studies relevant to child development, health, and the therapeutic use of animals.
There are currently 300 therapeutic proteins in the biopharmaceutical industry's development pipeline, while those already on the market will soon be out of patent and ripe for exploitation as generics.
EMD Serono, Kirschbaum says, «focuses on the development of targeted cancer therapies on three therapeutic platforms: targeting the tumor cell, the tumor environment, and the immune system.»
The discovery, published today in the journal Nature Communications, opens the door to the development of new therapeutic targets to fight these types of cancer.
These plaques are associated with development of Alzheimer's disease and several therapeutic strategies are aimed at reducing their formation and eliminating them.
The next objective of the researchers is to decode the action mechanism of TREX2 in the development and maintenance of psoriasis, so as to design new therapeutic strategies for the treatment of this disease.
Delays can have cascading and devastating effects on the development of a therapeutic.
The research, led by researchers from the Department of Pathology and Experimental Therapeutics of the Faculty of Medicine and Health Sciences of the University of Barcelona and the Bellvitge Biomedical Research Institute (IDIBELL), contributes to increase the knowledge about this complex and multi-factor inflammatory disease and opens doors to the development of new therapeutic strategies.
As a result, the emphasis in early development is on understanding the molecular underpinnings of disease and developing markers for therapeutic effects.
Determining the detailed molecular mechanism that mediates the therapeutic actions of cannabidiol may suggest development strategies for new drugs aimed at GPR55, according to the researchers.
«Using approved therapies for one condition to treat another, or drug repurposing, offers new avenues to speed Parkinson's therapeutic development,» said Dr Brian Fiske, senior vice president of research programs at MJFF.
They indicate that mammalian target of rapamycin (Mtor)- dependent inhibition is a viable therapeutic option to prevent the development of blast trauma - induced HO.
Their control requires the continuous development of new and potent antiviral drugs / therapeutic options.
The work published in Cancer Cell complements previous research efforts from the CNIO Melanoma Group, which could lead to the development of novel drugs that selectively target the mechanism of cell autodigestion as a potential therapeutic strategy.
«We are excited by the work of Dr. Pourdehnad and colleagues and believe these results are an important advance in understanding the role of myc pathway dysregulation in multiple myeloma, and ultimately allow for the development of therapeutic strategies to address it,» said Jeffrey Wolf, MD, a UCSF blood disorder specialist and director of the Stephen and Nancy Grand Multiple Myeloma Translational Initiative at UCSF, a sponsor of the research.
«While inclusion of such MIPs in a cosmetic product will require much formulation development, it is clear to see the potential of imprinting technology in a range of topical applications, both cosmetic and therapeutic.»