Throughout her career as a therapist, Amber has pursued training in a variety
of therapeutic models including Play Therapy, Theraplay, Emotional Transformation Therapy, Resonance Repatterning, Eye Movement Desensitization and Reprocessing (EMDR), Trauma Focused Cognitive Behavioral Therapy (TF - CBT), Psychodrama, and Art Therapy.
Throughout her career as a therapist, Lori has pursued training in a variety
of therapeutic models including Play Therapy, Theraplay, Psychodrama, Emotional Transformation Therapy, Resonance Repatterning, Eye Movement Desensitization and Reprocessing (EMDR), Trauma Focused Cognitive Behavioral Therapy (TF CBT) and Art Therapy.
Additional Information: Throughout her career as a therapist, Lori has pursued training in a variety
of therapeutic models including play therapy, Theraplay, Psychodrama, Emotional Transformation Therapy, Resonance Repatterning, Eye Movement Desensitization and Reprocessing (EMDR), Trauma Focused Cognitive Behavioral Therapy (TF CBT) and Art Therapy.
Analyze a variety
of therapeutic models for helping couples learn to transition into forgiveness and rebuild trust.
I use a variety
of therapeutic models and enjoy working with children of all ages and families from all backgrounds.
She utilizes a variety
of therapeutic models including Cognitive Behavioral Therapy, Client Centered Therapy, Eye Movement Desensitization and Reprocessing (EMDR), and Solution Focused Therapy.
Develop a trinocular description
of a therapeutic model or method currently being used, or of a specific client and their treatment process / plan.
Not exact matches
Pell is endlessly convicted by his critics
of being insufficiently
therapeutic,
of failing to
model emotiveness and bring about catharsis.
While this classic
model of addiction may like the
therapeutic sensibility underlying it, be
of limited value, it has significantly nuanced, if not displaced, the fat - sin equation so often debunked by critics
of evangelical diet literature.
Self - help groups (many
of which are
modeled on Alcoholics Anonymous) represent one
of the most hopeful developments in the whole field
of contemporary
therapeutic groups.
Also, attempts over the past generation to dispense with the pastoral
model in favor
of a
therapeutic one — in which the minister is one professional alongside others — have been unsatisfying.
Attempts over the past generation to dispense with the pastoral
model in favor
of a
therapeutic one — in which the minister is one professional alongside others — have been unsatisfying.
The
therapeutic ethic relies largely on a contract
model of a professional - client relationship: confidentiality is based on the dual needs
of respecting the individual and preserving the character
of relationships.
The union said reducing staff goes against the recommendations
of a consultant working with the task force who believes the agency will need more staffing to successfully move away from a correction
model to a more
therapeutic model of care.
Further studies in animal
models and patients (with altered TRPM7 channel function) have been initiated, in order to evaluate the efficacy and safety
of magnesium as a
therapeutic for this disease.
«Moving to non-invasive and repeatable methods
of nerve fiber measurements such as in vivo corneal confocal microscopy would enhance study
of peripheral neuropathy by enabling early detection
of damage, progression
of nerve fiber deterioration, and enable assessment
of therapeutic strategies in the SIV / macaque
model,» explains Dr. Mankowski.
We demonstrated that DENV serotype 2 (DENV2)-- specific human monoclonal antibody (HMAb) 2D22 is
therapeutic in a mouse
model of antibody - enhanced severe dengue disease.
For now, Rashid's group has a list
of candidate
therapeutic drugs that they'll test in their new liver disease
models, something that may still prove useful to patients.
«We know that 70 - 75 percent
of glioblastoma patients undergo surgery for tumor debulking, and we have previously shown that MSCs encapsulated in biocompatible gels can be used as
therapeutic agents in a mouse
model that mimics this debulking,» he continued.
From accelerating the identification and validation
of novel
therapeutic targets, to creating better animal
models of human diseases in a shorter time frame, to reducing the number
of failed products, Crispr looks set to shave millions off R&D costs and boost drug discovery, she says.
Instead
of systematically testing the effects
of known compounds — the pharmaceutical industry's basic
model for more than a century — scientists can now investigate backward, combing through genomic data to find links between specific genotypes and diseases and then screening drug data to identify
therapeutic candidates.
Because the researchers found that CTLA4Ig was effective in suppressing hepatitis in this study, they suggest that CTLA4Ig should be among the
therapeutic options investigated further as a potential therapy for patients with severe acute hepatitis B. To this end, this animal
model is useful for virological and immunological analysis
of HBV infection.
This new technology offers two main advantages based on the use
of molecular tools to manipulate the genome: firstly, working
models that had not existed up until now for the study
of tumour biology and, secondly, their application will eventually allow for the study
of new
therapeutic targets and therapies.
Treatment in a mouse
model of metastatic breast cancer with two
of the down - regulated miRNAs (miR - 141 and miR - 219) suppressed bone metastases, suggesting that these miRNAs may have
therapeutic utility.
Building on these findings, the researchers demonstrated the utility
of their T cell expansion platform in a
therapeutic model.
Shah next plans to rationally combine the toxin - secreting stem cells with a number
of different
therapeutic stem cells developed by his team to further enhance their positive results in mouse
models of glioblastoma, the most common brain tumor in human adults.
«Our work and that
of our colleagues on stress and CRF have been mechanistically implicated in Alzheimer's disease, but agents that impact CRF signaling have not been carefully tested for
therapeutic efficacy or long - term safety in animal
models,» said the study's principal investigator and corresponding author Robert Rissman, PhD, assistant professor in the Department
of Neurosciences and Biomarker Core Director for the Alzheimer's Disease Cooperative Study (ADCS).
Recently, Dr. Cohen's laboratory obtained an ethical approval to test the
therapeutic efficiency
of NT219 as a treatment in Alzheimer's -
model mice, hoping to develop a future treatment for hitherto incurable neurodegenerative disorders.
«Network
model of the musculoskeletal system predicts compensatory injuries: The authors» simplified musculoskeletal
model could lead to clinical developments for testing
therapeutic responses to injury.»
The study, called «Molecular Determinants
of Drug - Specific Sensitivity for Epidermal Growth Factor Receptor (EGFR) Exon 19 and 20 Mutants in Non-Small Cell Lung Cancer,» and published online in the journal Oncotarget, demonstrates how computer
modeling of EGFR mutations found in lung cancer can elucidate their molecular mechanism
of action and consequently optimize the selection
of therapeutic agents to treat patients.
The paper, by S.S. Karuppagounder at Burke Medical Research Institute in White Plains, N.Y., and colleagues was titled, «
Therapeutic targeting
of oxygen - sensing prolyl hydroxylases abrogates ATF4 - dependent neuronal death and improves outcomes after brain hemorrhage in several rodent
models.»
But this remarkable
therapeutic benefit isn't limited to MS. Previous research in animal
models that mimic other diseases suggest that certain forms
of amyloids can ease damage from strokes, traumatic brain injuries and even heart attacks.
To study the suitability
of guanabenz as a
therapeutic after MS symptoms have already appeared and peaked, the researchers used a mouse
model in which symptoms relapse and remit — cycling from high severity to low severity to high again over time.
«Although this is basic scientific research using animal
models, these studies are shedding light on the molecular mechanisms that control male fertility, and are helping us to better understand the causes
of many cases
of infertility and enabling new horizons to be opened up in the development
of therapeutic targets and strategies to combat it,» explained Dr Subirán.
«Use
of such a clinically - relevant large animal
model allows us to begin tackling the next challenges on the road to translating this novel
therapeutic strategy to human patients.»
The CUMC team is currently using the new mouse
model to study signaling pathways in the brain that drive anorexic behavior, with the ultimate goal
of identifying
therapeutic targets.
«We report much higher
therapeutic efficacy in preclinical brain tumor
models using the combination
of both therapies, leading to an increase in median survival,» Lowenstein says.
Dr. Zhu said he believes the study provides the scientific community with an important animal
model to further investigate ARID1B's role in human brain disorders and will be a useful tool for
therapeutic testing
of potential treatments for autism, intellectual disability, and Coffin - Siris syndrome.
«The induced pluripotent stem cells we used in this study proved to be extremely useful in disease
modelling, and they could offer an excellent platform for drug discovery and testing new
therapeutic targets for Alzheimer's disease in the future,» says Early Stage Researcher Minna Oksanen, the lead author
of the study.
In a new study, published online June 6 in Nature, researchers at University
of California San Diego School
of Medicine and Moores Cancer Center, together with colleagues at Keio University, the University
of Nebraska and Ionis Pharmaceuticals describe an innovative new
model that not only allowed them to track drug resistance in vivo, but also revealed a new
therapeutic target, which early testing suggests could provide a strategy to arrest pancreatic cancer growth.
Metabolites derived from the microbiome block protein misfolding in test tubes and prevent neurodegeneration in a fly
model of a disease related to Parkinson's, hinting that gut - derived metabolites may hold
therapeutic promise (Lap Ho, abstract 573.23, see attached summary).
The study
of these new mouse
models means an advance in the knowledge
of disease's development mechanisms and an opportunity to implement new
therapeutic strategies for patients.
Interestingly, the team showed that combining anti-angiogenic and immune - stimulating therapies in the treatment
of tumors in mouse
models resulted in better
therapeutic outcomes by providing white blood cell gates through which they can infiltrate cancers.
To test the capsule's real - world applications, the team used both mathematical
modeling and animal
models to investigate the effects
of delivering a sustained
therapeutic dose
of a drug called ivermectin, which is used to treat parasitic infections such as river blindness.
«Our results in experimental
models of cancer suggest a new
therapeutic strategy based on inhibiting the microRNA machinery — or the Let - 7 microRNAs — specifically in the TAMs, which may unleash the power
of mainstream immunotherapies, such as immune checkpoint inhibitors.»
In mouse
models of cancer, targeted
therapeutic inhibition
of translation disrupts this survival response, dramatically slowing tumor growth and potentially rendering drug - resistant tumors vulnerable to other therapies.
Sensitive and analogous behavioral assays in animal
models and humans are needed to improve the translational predictability
of therapeutic strategies.
In the case
of influenza, mAbs have been shown to provide prophylactic or
therapeutic protection in mice and other animal
models (Reuman et al., 1983; Sweet et al., 1987; Palladino et al., 1995; Renegar et al., 2004).
Several tests in cultured cells indicated that ganciclovir would cause the death
of HSV - TK - expressing stem cells, and testing in the mouse
model confirmed that administration
of the drug after successful treatment
of brain metastases successfully eliminated
therapeutic stem cells that also expressed HSV - TK.
Tagged
therapeutic stem cells (green) are targeting breast cancer metastases (red) in the brain
of a mouse
model.