Sentences with phrase «of transforming growth factor»

In an article published online April 5, 2018 by JCI Insight, the researchers showed that a specific form of transforming growth factor (TGF)- beta binds the membrane receptor glycoprotein - A...

Myostatin (GDF - 8), a member of the transforming growth factor - beta (TGF -?)

Myostatin, a member of the transforming growth factor - beta superfamily, is a negative regulator of skeletal muscle growth.1 Meaning that it limits the size and level of skeletal muscle growth.

While the cause of changes in aqueous humor outflow resistance remain unclear, it has been established that the amount of transforming growth factor - beta2 (TGF - Î ² 2) is increased by 60 - 70 % in the aqueous humor of POAG patients.

Some corneas were wounded to determine whether the wounded areas stimulated BrdU (by staining or fluorescence) followed by the synthesis of transforming growth factor beta (TGFβ).

A proposed mechanism for shutting down cell division, following a challenge such as wounding, may be due to the appearance of transforming growth factor β (TGFβ)[1].

Dr. Doyle then trained as a postdoctoral scholar at Stanford University under the mentorship of Dr. Marion Buckwalter, researching the role of transforming growth factor (TGF)- beta signaling after stroke and developing a model of poststroke dementia.

Not exact matches

What they discovered was that an inflammatory factor known as TGF - beta (transforming growth factor - beta) can give cancer cells properties of immune cells by supplying the surface of the cancer cell with a receptor that normally only exists on the white blood cells that travel through the lymphatic system.

A major challenge in creating any type of organoid is determining the unique mixture of nutrients, growth factors, and tissue culture techniques that will transform patient tumor cells into miniature tumor organoids in a petri dish.

As a result, they gained new understanding of how a substance known as transforming growth factor triggers cell transformations.

In the course of their research, they found that the protein transforming growth factor B1 (TGF - B1), contained in megakaryocytes, signaled quiescence of hematopoietic stem cells.

Joyce et al. [1] have suggested that transforming growth factor - β2 (TGF - β2) may keep HCECs in a non-replicative state in the absence of contact inhibition.

Platelet - derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus.

Human stem / progenitor cells from bone marrow enhance glial differentiation of rat neural stem cells: a role for transforming growth factor β and Notch signaling.

In addition to p53, there are other transcriptional activatory mechanisms that are not well understood for the most part and which operate in response to mitogenic stimulation (11, 12), transforming growth factor - β (13, 14, 15), and aberrant oncogenic signals (16, 17) or during a number of cell differentiation processes (18, 19).

Cell contact, prostaglandin E (2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4 + CD25 (High) forkhead box P3 + regulatory T cells.Clin Exp Immunol 2009; 156: 149 - 160.

Increased transforming growth factor beta expression inhibits cell proliferation in vitro, yet increases tumorigenicity and tumor growth of Meth A sarcoma cells.

Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor - β.

The supernatant of apoptotic cells causes transcriptional activation of hypoxia - inducible factor — 1α in macrophages via sphingosine -1-phosphate and transforming growth factor - β.

Sp1 binds to the GC - rich sequence on the proximal region of p21waf1 / cip1 promoter and acts as a mediator for the induction of p21waf1 / cip1 gene caused by transforming growth factor β (TGF - β; ref.

This leads to regulatory T - cell development, subsequent interleukin (IL)-10 and transforming growth factor beta secretion, and ultimate suppression of the immune response.

Abbreviations: ACVR2A, activin A receptor type IIA; BMP, bone morphogenetic protein; BMPR, BMP receptor, type II; CNS, Central nervous system; DA, dopaminergic; DMEM / F12, Dulbecco's modified Eagle's medium nutrient mixture F - 12; E, embryonic day; GDF, growth differentiation factor; GO, gene ontology; KEGG, Kyoto encylopedia of genes and genomes; MAPK, Mitogen - activated protein kinase; mDA, midbrain dopaminergic; PD, Parkinson's disease; RIPA, radioimmunoprecipitation assay; SN, Substantia nigra; TGF - β, transforming growth factor - β; TH, tyrosine hydroxylase; VM, ventral midbrain / mesencephalon; Zeb2, Zinc finger E-box-binding homoeobox 2

Expression of mTert in primary murine cells links the growth - promoting effects of telomerase to transforming growth factor - beta signaling.

In clinical trials, it has been shown to induce transforming growth factor - beta, triggering the accumulation of extracellular matrix, which continues through the remodeling phase of wound repair.

Studies by his team and others indicate that these fields can increase a joint's production of natural anti-inflammatory agents, such as transforming growth factor - beta.

Furthermore, higher concentrations of IL - 2, IL - 4, IL - 1β and transforming growth factor -(TGF - α) were found in ventricular CSF in juvenile PD patients (vs healthy controls).»

Conserved linkage of early growth response 4, annexin 4, and transforming growth factor alpha on mouse chromosome 6.

* 1 Andrew Potts (Affordable Housing Party) platform includes: Climate change and environmental degradation are symptoms of overpopulation and we want to correct Australia's rapid population growth which is also one of a number of factors contributing to housing unaffordability in Australia * 2 Peter Wills (Greens) platform includes: CLIMATE CHANGE AND ENERGY The climate challenge is also an opportunity to transform Australia into a carbon - neutral powerhouse that creates new jobs and a cleaner planet.

«Combine all these factors in with the growth of the Health Sciences industry, from both a service provider and employment perspective; expansion of cultural and entertainment venues; reemergence of the transportation services, including both commuter rail and airport services; the ever - increasing higher education capacity of the nine major colleges and universities in the city and five additional in the region; the continued expansion and success of both «Restaurant Row», Shrewsbury Street and the transforming of the Canal District, and who could ask for more?