The following institutions contributed to the study: Technical University of Munich (Central Institute
of Translational Cancer Research, Clinic and Policlinic for Internal Medicine II, Institute of Pathology), DKTK and DKZF Heidelberg; The Wellcome Trust Sanger Institute, Cambridge; Ludwig - Maximilians Universität (Anthropology & Human Genomics und Innere Medizin II des Klinikums Großhadern), Helmholtz Zentrum München (Research Unit Radiation Cytogenetics); Universidad de Oviedo (Bioquímica y Biología Molecular, IUOPA und CINN - CSIC), Instituto de Medicina Oncológica y Molecular de Asturias (IMOMA), Oviedo, University of Cambridge (Department of Veterinary Medicine), Instituto de Medicina Oncológica y Molecular de Asturias, Instituto de Biomedicina y Biotecnología de Cantabria.
The study is published in the October 2016 issue
of Translational Cancer Research.
Not exact matches
But Mohler, senior vice president for
Translational Research at Roswell Park
Cancer Institute, responded that Albany needs to have a greater sense
of urgency.
Professor Paolo Boffetta (MD), the Annals
of Oncology associate editor for epidemiology and Director
of the Institute
of Translational Epidemiology at the Icahn School
of Medicine at Mount Sinai in New York (USA), commented: «These results are extremely important in showing that reducing
cancer mortality can be achieved: priority should be given to
research in
cancers with unfavourable trends, such as pancreatic
cancer, and in reducing
cancer mortality disparities, both between countries (Central / Eastern versus Western Europe), and within countries, for example, between socioeconomic groups.
The
research, which builds on previous work by Dr. Rassool and Dr. Baylin, was funded by a number of grants, including Stand Up To Cancer's inaugural Laura Ziskin Prize in Translational Research — a $ 250,000 grant awarded to the two researchers
research, which builds on previous work by Dr. Rassool and Dr. Baylin, was funded by a number
of grants, including Stand Up To
Cancer's inaugural Laura Ziskin Prize in
Translational Research — a $ 250,000 grant awarded to the two researchers
Research — a $ 250,000 grant awarded to the two researchers in 2012.
Using genomic analysis to study
cancer in dogs can help develop new therapies for humans with cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (
cancer in dogs can help develop new therapies for humans with
cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (
cancer, according to a proof -
of - concept study led by the National
Cancer Institute (NCI) and the Translational Genomics Research Institute (
Cancer Institute (NCI) and the
Translational Genomics
Research Institute (TGen).
Focusing on basic
research for the functional regulation
of innate and adaptive immunity and on
translational research for
cancer immunotherapies, the National Key Laboratory
of Medical Immunology has been conducting innovative
research and exploration, and is becoming a rising star in the international immunology community.
So how are these huge shifts in the
research firmament — multidisciplinarity, translational research, and commercialization — affecting one of the largest funders of basic biomedical science in the country, Cancer Rese
research firmament — multidisciplinarity,
translational research, and commercialization — affecting one of the largest funders of basic biomedical science in the country, Cancer Rese
research, and commercialization — affecting one
of the largest funders
of basic biomedical science in the country,
Cancer ResearchResearch UK?
A team under Professor Scheffler, consisting
of researchers from the Bonn University Hospital, the Life & Brain Center, The German Consortium for
Translational Cancer Research, Tufts University Boston / Massachusetts, and other institutes in the USA, has now developed a new method that is expected to combat such complex brain tumors better.
Looking ahead,
cancer research looks set to thrive — particularly in the
translational research arena and the development
of new therapeutics.
His
research efforts are divided between preclinical models, the development, performance, and monitoring
of cancer immunotherapy trials and the training
of the next generation
of translational investigators.
Lymphoma Genomic
Translational Research Laboratory, Division
of Medical Oncology, National
Cancer Centre Singapore, Singapore 169610, Singapore.
The University
of Sheffield's Department
of Oncology and Metabolism conducts world - class
research from basic clinical and
translational cancer research to life course
research and basic level biology through to diseases such as diabetes and osteoporosis.
The lab
of co-author Dr. Robert Bast Jr., an expert in ovarian
cancer and vice president for
translational research at MD Anderson, inserted gel - bound carbon nanotubes into the ovaries
of rodents to mimic the accumulations that are expected for nanotubes linked to special antibodies that recognize tumor cells.
«The exciting
research results being presented today underscore how transplants are becoming an increasingly successful treatment option for more patients with blood
cancer than ever before,» said Jeffrey Miller, MD, moderator of the press conference and Deputy Director of the Masonic Cancer Center and the Clinical and Translational Sciences Institute at the University of Minnesota in Minnea
cancer than ever before,» said Jeffrey Miller, MD, moderator
of the press conference and Deputy Director
of the Masonic
Cancer Center and the Clinical and Translational Sciences Institute at the University of Minnesota in Minnea
Cancer Center and the Clinical and
Translational Sciences Institute at the University
of Minnesota in Minneapolis.
The finding warrants
research into adding drugs that could prevent the
cancer from hijacking patients» repressive gene regulatory machinery, which might allow the original therapy to work long enough to eradicate the tumor, the researchers report in their National Institutes
of Health - funded study, published in the current issue
of Science
Translational Medicine.
Her
research is both
translational and clinical in nature and centers on the human genetics
of healthy skin aging and diseases related to aging skin, including new treatments for advanced basal cell skin
cancers.
«AML is a disease in which fewer than 30 percent
of patients are cured,» said co-senior author Ulrich Steidl, M.D., Ph.D., associate professor
of cell biology and
of medicine and the Diane and Arthur B. Belfer Faculty Scholar in
Cancer Research at Einstein and associate chair for translational research in oncology at Mon
Research at Einstein and associate chair for
translational research in oncology at Mon
research in oncology at Montefiore.
The results
of the study were published this week in the journal Nature Medicine from researchers at Penn's Abramson
Cancer Center, including senior author Carl H. June, MD, the Richard W. Vague Professor in Immunotherapy in the department
of Pathology and Laboratory Medicine and director
of Translational Research in the ACC, the University
of Maryland School
of Medicine, and Adaptimmune Therapeutics plc (Adaptimmune).
Joining forces with dermatologists and oncologists from the University Hospital in Zurich and backed by the University
Research Priority Program «
Translational Cancer Research,» Sommer's team was able to demonstrate that, in melanoma cells, the epigenetic factor EZH2 controls genes that govern tumor growth as well as genes that are important for the formation
of metastases.
«High dose steroids is the only proven treatment for GVHD,» said James L. M. Ferrara, MD, DSc, Ward - Coleman Chair in
Cancer Medicine Professor at the Icahn School
of Medicine at Mount Sinai, Director
of Hematologic Malignancies
Translational Research Center at Tisch
Cancer Institute at Mount Sinai.
«It's a dramatic increase in lifespan
of animal models, as much as 25 percent,» said Leyuan Liu, PhD, assistant professor at the Texas A&M Institute
of Biosciences and Technology's Center for
Translational Cancer Research.
The
Translational Genomics
Research Institute (TGen) has uncovered possible genetic origins
of breast
cancer that spreads to the brain, according to a first -
of - its - kind study published in the scientific journal PLOS ONE.
What we are changing is the amount
of time that the formulation needs to be there, because we're accelerating how the drug enters the tissue,» says Giovanni Traverso, a
research affiliate at MIT's Koch Institute for Integrative Cancer Research, a gastroenterologist at MGH, and one of the senior authors of a paper describing the technique in the Oct. 21 issue of Science Translational M
research affiliate at MIT's Koch Institute for Integrative
Cancer Research, a gastroenterologist at MGH, and one of the senior authors of a paper describing the technique in the Oct. 21 issue of Science Translational M
Research, a gastroenterologist at MGH, and one
of the senior authors
of a paper describing the technique in the Oct. 21 issue
of Science
Translational Medicine.
The
research team is led by Carl June, MD, the Richard W. Vague Professor in Immunotherapy in the department of Pathology and Laboratory Medicine and director of Translational Research in the Abramson Cancer Center, along with David Porter, MD, the Jodi Fisher Horowitz Professor in Leukemia Care Excellence and director of Blood and Marrow Transplantation in the Abramson Cancer
research team is led by Carl June, MD, the Richard W. Vague Professor in Immunotherapy in the department
of Pathology and Laboratory Medicine and director
of Translational Research in the Abramson Cancer Center, along with David Porter, MD, the Jodi Fisher Horowitz Professor in Leukemia Care Excellence and director of Blood and Marrow Transplantation in the Abramson Cancer
Research in the Abramson
Cancer Center, along with David Porter, MD, the Jodi Fisher Horowitz Professor in Leukemia Care Excellence and director
of Blood and Marrow Transplantation in the Abramson
Cancer Center.
Bringing together bench and bedside is the purpose
of a new institute that aims to become a world - class «
translational»
cancer research centre, where the knowledge gained from basic
research is translated into clinical applications.
The effort is the fruit
of a new model
of translational research being pursued at the Wyss Institute for Biologically Inspired Engineering at Harvard University that integrates the latest
cancer research with bioinspired technology development.
This advance in breast
cancer research reflects the mission
of Stem Cell Reports to provide an open - access forum that communicates basic discoveries in stem cell
research as well as
translational and clinical studies.
«An important
translational implication
of this
research is that we hope that by combining Notch inhibitors with drugs that target B - cell signaling we can better treat these B - cell
cancers,» said senior author Warren Pear, MD, PhD, a professor
of Pathology and Laboratory Medicine at Penn Medicine.
Dr. Mardis received the Scripps
Translational Research award for her work on
cancer genomics in 2010, and was named a Distinguished Alumni
of the University
of Oklahoma College
of Arts and Sciences for 2011.
In this webinar, a panel
of experts will discuss their
research and describe the use
of real - time, label - free cell monitoring in their investigation
of novel
cancer targets and the impact
of their work on
translational research and drug development.
February 10, 2006 $ 25 million gift from Jules and Gwen Knapp will help build 10 - story medical
research facility at the University
of Chicago Jules and Gwen Knapp
of Chicago have donated $ 25 million toward construction
of a 330,760 - square - foot, 10 - story, state -
of - the - art facility that will provide a new home for
translational research programs in children's health,
cancer, and other medical specialties at the University
of Chicago.
«Pin1 changes protein shape through proline - directed phosphorylation, which is a major control mechanism for disease,» explains co-senior author Kun Ping Lu, MD, PhD, Director
of Translational Therapeutics in the
Cancer Research Institute at BIDMC and Professor
of Medicine at Harvard Medical School who co-discovered the enzyme in 1996.
The goal
of the Center for Clinical and
Translational Sciences (CCTS) is to facilitate clinical and translational research at UTHealth, The University of Texas MD Anderson Cancer Center and the Memorial Hermann Hos
Translational Sciences (CCTS) is to facilitate clinical and
translational research at UTHealth, The University of Texas MD Anderson Cancer Center and the Memorial Hermann Hos
translational research at UTHealth, The University
of Texas MD Anderson
Cancer Center and the Memorial Hermann Hospital System.
«RNAi therapies are a unique approach to
cancer treatment as they have the potential to «turn off» the genes» coding for proteins involved in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&
cancer treatment as they have the potential to «turn off» the genes» coding for proteins involved in
cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&
cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director
of the Virginia G. Piper
Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&
Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director
of the Clinical
Translational Research Division
of the
Translational Genomics
Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a
cancer cell to block the expression of specific proteins involved in tumor growth.&
cancer cell to block the expression
of specific proteins involved in tumor growth.»
The Medical Center includes the School
of Medicine and the School
of Nursing & Health Studies, both nationally ranked; Georgetown Lombardi Comprehensive
Cancer Center, designated as a comprehensive cancer center by the National Cancer Institute; and the Biomedical Graduate Research Organization, which accounts for the majority of externally funded research at GUMC including a Clinical and Translational Science Award from the National Institutes of H
Cancer Center, designated as a comprehensive
cancer center by the National Cancer Institute; and the Biomedical Graduate Research Organization, which accounts for the majority of externally funded research at GUMC including a Clinical and Translational Science Award from the National Institutes of H
cancer center by the National
Cancer Institute; and the Biomedical Graduate Research Organization, which accounts for the majority of externally funded research at GUMC including a Clinical and Translational Science Award from the National Institutes of H
Cancer Institute; and the Biomedical Graduate
Research Organization, which accounts for the majority of externally funded research at GUMC including a Clinical and Translational Science Award from the National Institutes of
Research Organization, which accounts for the majority
of externally funded
research at GUMC including a Clinical and Translational Science Award from the National Institutes of
research at GUMC including a Clinical and
Translational Science Award from the National Institutes
of Health.
The designation recognizes the Center's collaborative environment and expertise in harnessing
translational research to bridge scientific discovery to clinical delivery, with the ultimate goal
of successfully introducing novel diagnostic, therapeutic and preventive approaches to
cancer.
About the Anna - Maria Kellen Clinical Accelerator The Anna - Maria Kellen Clinical Accelerator, the clinical
research program of the Cancer Research Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede inn
research program
of the
Cancer Research Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede innov
Cancer Research Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede inn
Research Institute, leverages CRI's partnerships with nonprofit organizations, pharmaceutical and biotech companies, and academic
research and treatment centers worldwide, to provide scientists and clinicians with expertise in cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede inn
research and treatment centers worldwide, to provide scientists and clinicians with expertise in
cancer immunotherapy access to resources they need to advance ambitious clinical and translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede innov
cancer immunotherapy access to resources they need to advance ambitious clinical and
translational research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede inn
research ideas, while simulataneous solving for competitive and regulatory hurdles that would otherwise impede innovation.
Funding: NIH's National Institute
of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Heart, Lung, and Blood Institute (NHLBI), National Institute on Aging (NIA), National Center for Advancing
Translational Sciences (NCATS), National
Cancer Institute (NCI), and National Human Genome
Research Institute (NHGRI); and many other funding entities (see reference paper for the full list).
The Department
of Translational Hematology and Oncology
Research (THOR) conducts cancer research to develop and make available novel diagnostic tools, targeted therapies and clinical trials for direct use in patie
Research (THOR) conducts
cancer research to develop and make available novel diagnostic tools, targeted therapies and clinical trials for direct use in patie
research to develop and make available novel diagnostic tools, targeted therapies and clinical trials for direct use in patient care.
Dr Peter Sneddon,
Cancer Research UK's executive director of clinical and translational research funding, said: «We are delighted that Professor Ashworth has won this well deserve
Research UK's executive director
of clinical and
translational research funding, said: «We are delighted that Professor Ashworth has won this well deserve
research funding, said: «We are delighted that Professor Ashworth has won this well deserved award.
At the dinner, Parker also received the organization's highest honor for lay individuals, the Oliver R. Grace Award for Distinguished Service in Advancing
Cancer Research, for his outspoken endorsement of cancer immunotherapy and substantial financial support of the Cancer Immunology Translational Research Dream Team that is jointly funded by CRI and Stand Up To Cancer, an organization to which Parker has strong
Cancer Research, for his outspoken endorsement
of cancer immunotherapy and substantial financial support of the Cancer Immunology Translational Research Dream Team that is jointly funded by CRI and Stand Up To Cancer, an organization to which Parker has strong
cancer immunotherapy and substantial financial support
of the
Cancer Immunology Translational Research Dream Team that is jointly funded by CRI and Stand Up To Cancer, an organization to which Parker has strong
Cancer Immunology
Translational Research Dream Team that is jointly funded by CRI and Stand Up To
Cancer, an organization to which Parker has strong
Cancer, an organization to which Parker has strong ties.
The Clinical Accelerator, building on 60 + years
of CRI's dedication to funding the most innovative basic science in tumor immunology, enables experts to advance their most ambitious clinical and
translational research ideas to cure
cancer, and accelerates studies that one group or company could not do alone.
Andre Goy, MD, MS Chairman and Director, Chief
of Lymphoma Director, Clinical and
Translational Cancer Research John Theurer
Cancer Center at Hackensack University Hackensack Meridian Health Professor
of Medicine, Georgetown University Hackensack, NJ
Winship
Cancer Instituteâ $ ™ s Ned Waller and researchers from Childrenâ $ ™ s Healthcare
of Atlanta and Yerkes National Primate
Research Center were part
of a recent Science
Translational Medicine paper that draws a bright red circle around aurora kinase A as a likely drug target in graft - vs - host disease.
With a team
of over 200 researchers, Sanford
Research is comprised of eight groups that bridge bench, translational and clinical research including: Cancer Biology and Immunotherapies, Pediatrics and Rare Diseases, Diabetes, Cellular Therapies and Stem Cell Biology, Enabling Technology, Environmental Influences on Health and Disease, Genetics and Genomics, and Population
Research is comprised
of eight groups that bridge bench,
translational and clinical
research including: Cancer Biology and Immunotherapies, Pediatrics and Rare Diseases, Diabetes, Cellular Therapies and Stem Cell Biology, Enabling Technology, Environmental Influences on Health and Disease, Genetics and Genomics, and Population
research including:
Cancer Biology and Immunotherapies, Pediatrics and Rare Diseases, Diabetes, Cellular Therapies and Stem Cell Biology, Enabling Technology, Environmental Influences on Health and Disease, Genetics and Genomics, and Population Health.
(The Stand Up to
Cancer Prostate
Cancer Foundation Prostate Dream Team
Translational Cancer Research Grant is made possible by the generous support
of the Movember Foundation.
SEATTLE, Feb. 05, 2018 (GLOBE NEWSWIRE)-- NanoString Technologies, Inc. (NASDAQ: NSTG), a provider
of life science tools for
translational research and molecular diagnostic products, today announced the publication
of a landmark study in which Danish researchers used the Prosigna ® Breast
Cancer Assay risk of recurrence (ROR) score to accurately predict rates of 10 - year distant recurrence (DR) of cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 and
Cancer Assay risk
of recurrence (ROR) score to accurately predict rates
of 10 - year distant recurrence (DR)
of cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 and
cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with early - stage hormone receptor (HR)- positive, Her - 2 negative breast
cancer who received 5 years of adjuvant endocrine therapy according to nationwide guidelines between 2000 and
cancer who received 5 years
of adjuvant endocrine therapy according to nationwide guidelines between 2000 and 2003.
The system is available in the multi-mode FLEX configuration, which is designed to meet the needs
of high - complexity clinical laboratories seeking a single platform with the flexibility to run the Prosigna Breast
Cancer Assay and, when operated in the «Life Sciences» mode, process
translational research experiments and multiplexed assays developed by the laboratory.
Our researchers in the Center for Childhood
Cancer are conducting basic science, translational and clinical research geared toward finding a cure for childhood cancer and improving the toxicity of current treat
Cancer are conducting basic science,
translational and clinical
research geared toward finding a cure for childhood
cancer and improving the toxicity of current treat
cancer and improving the toxicity
of current treatments.