Sentences with phrase «of transport proteins»

Transport proteins: A series of transport proteins (multi drug resistant proteins, or MRPs) are responsible for getting the conjugated mercury out of your cells and into your blood, as well as from your blood into your liver and small intestine, and into other places so it can be eliminated

New supercomputer simulations have revealed the role of transport proteins called efflux pumps in creating drug - resistance in bacteria, research that could lead to improving the drugs» effectiveness against life - threatening diseases and restoring the efficacy of defunct antibiotics.

People with the transthyretin amyloidosis have mutations in the DNA of the transthyretin gene, which causes abnormal buildup and deposits of a transport protein called transthyretin in nerve and heart cells.

Two key events enabled organelles to develop: The precursor bacteria transferred many of their genes to the host's genome, and they developed a method of transporting the proteins produced by these and other genes back inside their own membranes.

The flowers of petunias that made normal amounts of the transport protein PhABCG1 (top row) are larger and healthier than the flowers of petunias engineered to produce less of the protein.

Hartnup's disease is a hereditary (autosomal recessive) disorder in which the absorption of tryptophan and certain other amino acids in the small intestine and their reabsorption in the kidneys is reduced due to a lack of a transport protein, which may lead to tryptophan deficiency and this in turn to vitamin B3 (niacin) deficiency [6].

Fructose absorption depends on the amount of transport protein GLUT5 in the small intestinal wall.

Not exact matches

Amino acids are the building blocks of protein, assisting with the maintenance of lean muscle mass, transport of nutrients, tissue repair and immunity.

He eats the protein truffles one bite at a time and is transported to the land of deliciousness.

When considering the protein source, for example, one must not only consider whether an animal - or plant - based protein will be used, but the specific organism from which it is derived (e.g., animal: chicken, beef, lamb, pork, etc.; fish: salmon, menhaden, etc.; plant: corn gluten meal, soybean meal, etc.), what part (s) of that organism will be included (e.g., plant: whole wheat vs. wheat germ vs. wheat bran; animal: entire animal vs. skeletal muscle vs. organ meats), and the form in which it will be added (animals: frozen, fresh, meal), all of which affect the diet in terms of cost, nutrient composition and stability, manufacturing requirements, and ingredient handling, transport, and storage.

Because triglycerides and cholesterol can't dissolve in blood, they circulate throughout your body with the help of proteins that transport the lipids (lipoproteins).

Genes significantly expressed across all stages of lactation are associated with making, modifying, transporting, and packaging milk proteins.

But in 2013, a research scientist in El - Naggar's laboratory, Sahand Pirbadian, discovered that these projections, referred to as «nanowires,» were actually extensions of the cell membrane covered in cytochromes — proteins containing iron that facilitate electron transport.

When looking for genes that might play important roles in the metabolism of healthy and cancerous liver cells, Wang and his colleagues became interested in a gene called SLC13A5, which produces a protein that transports citrate into cells.

Francis Barr, a junior research group leader at the Max Plank Institute of Biochemistry, studies protein transport.

These include more sensitive mass spectrometry for detecting, identifying and quantifying protein molecules, electron microscopy for visualizing an assortment of components of the nano - machine that transports toxins, and fluorescence confocal microscopy, which can label proteins with light emitting dyes.

Columbia researchers have uncovered new roles for proteins of the electron transport chain that implicate them in utilization of phenazines.

They found that the electron transport chain so critical to the conversion of electrons to energy can and is operating deep down in the oxygen - deprived biofilm and that in these environments, the bacterium depends on a specific part of the chain's terminal oxidase — a protein called CcoN4 — to access oxygen and grow normally.

Over the past 15 years, the GFP gene has enabled scientists to watch a plethora of previously murky biological processes in action: how nerve cells develop in the brain, how insulin - producing beta cells form in the pancreas of an embryo, how proteins are transported within cells, and how cancer cells metastasize through the body.

«Synthetic proteins help solve structure of the fluoride ion channel: Unexpected double - barreled «channsporter» structure suggests new mechanism for ion transport.»

The focus of their research is «exosomes», small virus - like particles that serve as «transport packages» for genetic material and proteins transmitted between cells.

The task of HLAs is to bind to fragments of proteins that are broken down in the cells, transport the fragments to the cell surface and present them to the T - lymphocytes.

A group of LMU physicists led by Professor Erwin Frey, in collaboration with Professor Stefan Diez (Technical University of Dresden and Max Planck Institute for Molecular Cell Biology and Genetics, Dresden), has now developed a model in which the motor proteins that are responsible for the transport of cargo along protofilaments also serve to regulate microtubule lengths.

Toward the end of her postdoc, Chacinska identified a protein called Mia40, whose role was to transport precursor proteins to the space lying between the outer and inner membranes of mitochondria.

What's more, a tweak Chacinska made to a standard experimental protocol allowed her lab to become the first to discover a mitochondrial protein transport mechanism based on the recognition of newly formed disulphide bonds.

Two theorists whose work set the stage for finding the Higgs boson won the Nobel Prize in physics this week, while three biologists who explored various aspects of how cells package, transport, and release their internal proteins earned the physiology or medicine prize.

Meanwhile, the selectors for the physiology or medicine prize honored three biologists who explored various aspects of how cells package, transport, and release their internal proteins.

To function, most of the newly - produced proteins first need to be sorted and then transported within and outside of the cell.

When the researchers administered drugs to inhibit the movement of certain «motor» proteins that transport mitochondria and other cargo within the cell by traveling along microtubules, the mitochondria accumulated in the axon of the neuron and never made it to the synaptic terminal.

Nielsen believes the secret is a bacterial pulley system of sorts: Oxygen - processing bacteria at the top connect to digestive microbes below via long protein threads that transport electrons.

Using fluorescence inside living cells as well as biochemistry, they showed that SMN promotes an interaction between the «zipcode» region of a test RNA and a transport protein.

Whether in a yeast cell or in a neuron, alpha synuclein directly interfered with the rate of production of proteins in the cell, and the transport of proteins between cellular compartments.

Both groups had unusually low levels of a protein that transports serotonin — a hormone involved in regulating mood — around the brain.

In both trials, levels of two proteins that play major roles in transporting beta - amyloid out of the brain as well as enzymes that degrade beta - amyloid increased significantly after administering oleocanthal.

Their major hurdle: to come up with a replacement for hemoglobin (an iron - enriched protein in red blood cells that transports oxygen from the lungs to the rest of the body) that can be directly introduced into the human circulatory system.

A protein that transports the simple chemical choline plays a major role in vesicle trafficking, ion homeostasis, and growth and development in plants, according to two new studies publishing 28 December in the open - access journal PLOS Biology, by Dai - Yin Chao of the Shanghai Institutes for Biological Sciences, China, and Sheng Luan of the University of California, Berkeley, USA, and co-workers.

Anthrax poisonings, as well as cholera infections, work in part by disrupting the normal transport mechanisms of proteins.

The study, «The nuclear transport receptor Importin - 11 is a tumor suppressor that maintains PTEN protein,» which will be published online February 13 in The Journal of Cell Biology, suggests that the loss of Importin - 11 may destabilize PTEN, leading to the development of lung, prostate, and other cancers.

Changes to the properties of the lipid bilayer component of the cell membrane can alter the function of proteins embedded in the membrane — proteins that regulate critical functions such as transport of materials in and out of the cell and communication with other cells.

The deficiency, they reasoned, would cause the rats to make more of the putative iron - transport protein, making it easier to find.

This small protein molecule contains a loop which fits, like a key in a lock, into the ion channel proteins found on nerve cell membranes, which are used to transport sodium and potassium ions in and out of the cell.

In 2016, Collins and colleagues published evidence of proteins on ostrich shells that were almost 4 million years old — the connection to human evolution may not be readily apparent, but such shells have been used by hominins for millions of years to transport water and other resources.

Members of the kinesin superfamily of motor proteins are essential for mitotic and meiotic spindle organization, chromosome segregation, organelle and vesicle transport, and many other processes that require microtubule - based transport.

The transport protein contains an ion binding site located at the center of the membrane that is composed of conserved amino acids.

As a cofactor of certain proteins, it plays an essential role in oxygen transport and metabolism.

«Structure of an iron - transport protein revealed.»

Ines Ehrnstorfer, a PhD student in the group of Professor Raimund Dutzler at the Department of Biochemistry of the University of Zurich, and her colleagues, have determined the first structure of an iron transport protein.

The researchers studied mutations that alter the function of hemoglobin, the protein in charge of transporting oxygen in the blood.

This vaccine uses an inactive herpes virus (stripped of its viral genes) to transport a small amount of Aß as well as another protein called interleukin - 4 that may help prevent brain inflammation.

In their Perspective, Knepper and Agre discuss an exciting study (Khademi et al.) that reports resolution of the crystallographic structure of a bacterial ammonia transport channel, AmtB, to an astonishing 1.35 angstroms, an amazing feat for an integral membrane protein.