Sentences with phrase «of tuberculosis bacteria»

French fur traders brought strains of the tuberculosis bacteria (inset) to Canada, where it spread to native populations.

The new drug cleared the mice of all tuberculosis bacteria after only 10 weeks of treatment.

Meanwhile, traditional antibiotics have led many strains of tuberculosis bacteria to evolve multi-drug resistance.

An outbreak in South Africa of an extremely drug - resistant strain of the tuberculosis bacterium is raising international alarm.

Not exact matches

What it does: This bacteria is most notorious for causing severe illnesses such as tuberculosis, leprosy, and Hansen's disease, though most species of mycobacteria in nature are benign in humans, unless in cases of those who have weakened immune systems.

Particularly striking is the mortality trend line for tuberculosis, which falls precipitously from 1838 onward — decades before the bacterium responsible for the disease was identified (1882), and long before the advent of the first effective antibiotic therapy, streptomycin.

About a third of the world's population is infected with TB - causing bacteria (Mycobacterium tuberculosis).

Despite having been vaccinated against the disease in 1989, which was 3 years before Sousa and her colleagues examined them, 58 % of the Indians had a weakened or nonexistent immune reaction in skin tests that measure cell response to the tuberculosis bacterium.

In tomorrow's issue of the Proceedings of the National Academy of Sciences, researchers report that more than half of the Yanomami people who had been vaccinated against TB do not produce a regular immune response to the tuberculosis bacterium.

But researchers now realize that it probably wasn't until the end of the Bronze Age that the bacteria evolved from a less virulent species that may have spread more like the flu, tuberculosis, or AIDS than the bubonic plague, which is transmitted through flea bites to the skin.

Tuberculosis (TB) tricks the immune system into attacking the body's lung tissue so the bacteria are allowed to spread to other people, new research from the University of Southampton suggests.

As a team of researchers from four European countries and South Korea report in Science today, a gene the group dubbed ethA2 is normally inactive in M. tuberculosis, so the bacteria hasn't had a chance to develop resistance to it.

In the test tube experiments, SMARt - 420 made ethionamide more potent in both ethionamide sensitive and resistant bacteria, and it worked against a wide range of M. tuberculosis strains.

The compounds have been shown to be effective in killing many species of bacterial pathogens but are generally less effective against the bacterium that causes tuberculosis.

Some strains of multidrug resistant tuberculosis (MDRTB) may have a lower fitness (be less capable of spreading) than drug - susceptible tuberculosis bacteria, according to a study published this week in PLOS Medicine.

Tuberculosis (TB) bacteria infect a third of the world's population and the disease kills 1.8 million people annually.

n many developing countries, a significant fraction of the tuberculosis burden comes potentially from the tuberculosis bacteria carried by animals, essentially cattle.

Its complex three - dimensional structure allows it to act simultaneously on two parts of a key enzyme in the tuberculosis bacillus, and in doing so, dramatically reduce the risk that the bacteria will develop multiple resistances.

Efforts to reduce the tuberculosis burden, therefore, must include strategies to reduce incidence of the bacteria in animals using «One Health» approach.

The goal is to find new ways to tackle the disease, which requires a thorough understanding of how the bacterium, known as Mycobacterium tuberculosis, behaves once it takes hold of the macrophages in our lungs.

The problems are not just in the South: poor people in the inner cities of the US are dying of tuberculosis because of a lethal mixture of overcrowding, HIV and drug - resistant strains of the TB bacterium.

TB, which is caused by the bacterium Mycobacterium tuberculosis, exploded in Russia and other former Soviet nations in the early 1990s, after the collapse of the Soviet Union and its health system.

M. bovis has also been isolated from humans only suffering from tuberculosis of the lungs and this may suggest that the bacterium is transmitted between people and not just between cattle and humans.

Working with a non-pathogenic cousin of M. tuberculosis called M. smegmatis, the team used a mutant form of the bacteria that lacked the part of RbpA that interacts with fidaxomicin.

In Western societies antibiotics had controlled menaces like tuberculosis and typhus, and the mechanisms of bacteria and viruses were well understood.

Professor De Voss said the scale of the threat, compounded by the emergence of increasingly drug - resistant strains of bacteria, meant it was vital to find new ways to combat tuberculosis.

«Since M. tuberculosis takes about a month to quantify using traditional approaches, any method that allows direct determination of the amount of bacteria present is very valuable and speeds progress, saving months every time an experiment is done,» Cirillo said.

In addition, when the scientists tested lansoprazole against a wide range of other bacteria, it proved to be highly selective for M. tuberculosis.

The TB bacterium Mycobacterium tuberculosis (Mtb) is estimated to be present in up to a third of the world's population, although active TB only develops in around one in 10 cases.

In a striking, unexpected discovery, researchers at Albert Einstein College of Medicine of Yeshiva University have determined that vitamin C kills drug - resistant tuberculosis (TB) bacteria in laboratory culture.

The bacterium that causes tuberculosis, Mycobacterium tuberculosis, or Mtb, previously was thought to infect the body only through inhalation and subsequent infection of cells in the lungs.

The innate system — via stem cells in the bone marrow — mobilizes macrophages, which are a type of white blood cell that swallows and kills invading bacteria like Mycobacterium tuberculosis (Mtb) that causes TB.

Subgroups of tuberculosis (TB)- causing bacteria can persist even when antibiotics wipe out most of the overall population.

New research suggests the bacteria that cause tuberculosis alter their metabolism to combat exposure to antimicrobials, and that these metabolic «escape pathways» might be neutralized by new drugs to shorten the troublesome duration of therapy.

Every March 24, on World TB Day, the global health community recognizes the work of Robert Koch, who announced on that date in 1882 his discovery of Mycobacterium tuberculosis, the bacteria that causes TB.

The researchers next showed that the Smurf1 gene controls M. tuberculosis growth in human macrophages and that the Smurf1 protein was found in association with bacteria in the lungs of patients with tuberculosis infections.

That result led to the current study, a collaboration between the Shiloh and Levine laboratories to determine if Smurf1 plays a similar role in the autophagy of bacteria like M. tuberculosis inside cells.

This is due, in part, to variations in antibiotic tolerance among subpopulations of Mycobacterium tuberculosis, the bacteria that cause tuberculosis.

The research team, led by Professor Paul Ortiz de Montellano in the US, investigated the impact of compounds related to cholesterol on the tuberculosis - causing bacterium Mycobacterium tuberculosis.

About one - third of the global population is infected with the bacteria that cause TB — Mycobacterium tuberculosis, or Mtb — though only a small percentage will develop the actual disease.

Scientists at the The University of Queensland and the University of California San Francisco have found a new way to inhibit the growth of the bacterium that causes tuberculosis (TB).

Scientists have discovered a new species of bacteria, Mycobacterium mungi, that causes tuberculosis (TB) and is transmitted through the skin and nose of banded mongoose in Northern Botswana.

The Dartmouth candidate, DAR - 901, is an inactivated vaccine made from a non-pathogenic bacterium that is genetically related to Mycobacterium tuberculosis, the cause of human tuberculosis.

Tuberculosis, leprosy, and Legionnaire's disease are infections caused by different species of bacteria.

The researchers were able to analyze the responses of individual bacteria to rifampicin, a core frontline antibiotic used to treat tuberculosis.

The results could be useful in guiding the future design of novel medicines against multidrug - resistant tuberculosis, malaria, diabetes and antibiotic - resistant bacteria.

VIC - 008 is a fusion protein combining an immune - activating protein from the tuberculosis bacteria with a small antibody fragment targeting mesothelin, a protein expressed in several types of tumor — including mesothelioma, pancreatic and ovarian cancer.

Today, approximately one - third of the world's population harbors Mycobacterium tuberculosis, the bacterium that causes TB.

Tuberculosis (TB) is a curable and preventable disease caused by the bacterium Mycobacterium tuberculosis and most often affects the lungs of infected Tuberculosis (TB) is a curable and preventable disease caused by the bacterium Mycobacterium tuberculosis and most often affects the lungs of infected tuberculosis and most often affects the lungs of infected individuals.

Washington State University scientists are addressing growing global concern about the spread of antimicrobial resistance in Africa, where the World Health Organization predicts that, by 2050, drug resistant tuberculosis and other bacteria could lead to the deaths of 4.15 million people each year.