Sentences with phrase «of tubulin»

Microtubules, hollow fibers of tubulin protein only a few nanometers in diameter, form the cytoskeletons of living cells and play a crucial role in cell division (mitosis) through their ability to undergo rapid growth and shrinkage, a property called «dynamic instability.»

This unique organization of tubulin is preserved among all living plant and animal cells, because it is essential for way in which microtubules assemble, Al - Bassam said.

In this situation, the microtubules continue to grow until the concentration of tubulins falls below a critical value.

Alpha tubulin is not suitable as a loading control in adipose tissue as expression of tubulin in adipose tissue is very low (Spiegelman and Farmer, Cell, 1982, 29 (1): 53 - 60, «in cells undergoing adipose differentiation actin synthesis decreases by 90 %»).

The basic unit of tubulin is a dimer of alpha - and beta - tubulin.

These hollow, cylindrical structures are made up of two types of tubulin protein — dubbed alpha and beta — which bond together into a single unit.

The NIMS group used nanotechnology to study conductive properties of individual microtubules, protein polymers of tubulin (the brain's most prevalent protein).

One reaction serves as a positive control to amplify a portion of the tubulin gene found in all plants, and the other assays for genetic modification.

It blocks (by 70 - 80 %) the ability of tubulin dimers (with GppNHp bound) to promote a stable inhibition of adenylyl cyclase.

Treatment of lung cancer cell lines with mebendazole caused mitotic arrest by depolymerization of tubulin, followed by apoptotic cell death.

We will use as an example the quantification of tubulin polyglycylation in wild - type testes and in Bug22 mutant testes, which present defects in the deposition of this posttranslational modification.

For the anticancer activity of mebendazole impairment of the organization of tubulin was identified as main intracellular effect in lung cancer, gastric cancer, leukemia and brain tumors [9, 20, 22, 25, 32].

Which of these becomes dominant depends on the relative concentrations of the tubulins and the motor proteins: In a certain concentration range the dynamic equilibrium between growth and shrinkage of the microtubules operates as it would if resources were not limiting.

Microtubules are hollow cylinders with walls made up of tubulin proteins — alpha (green) and beta (blue)-- plus EB proteins (orange) that can either stabilize or destabilize the structure of the tubulin proteins.