Costimulatory B7 - H1 in renal cell carcinoma patients: Indicator
of tumor aggressiveness and potential therapeutic target.
PC was assessed using Gleason scores
of tumor aggressiveness (< 6 or?
Not exact matches
«An index measures similarity between cancer cells and pluripotent stem cells: The new methodology measures
tumor aggressiveness and the risk
of relapse, helping doctors plan treatment.»
The activity
of four transcription factors — proteins that regulate the expression
of other genes — appears to distinguish the small proportion
of glioblastoma cells responsible for the
aggressiveness and treatment resistance
of the deadly brain
tumor.
A form
of genetic variation, called differential RNA splicing, may have a role in
tumor aggressiveness and drug resistance in African American men with prostate cancer.
«An index measures similarity between cancer cells and pluripotent stem cells: The new methodology measures
tumor aggressiveness and the risk
of relapse, helping doctors plan treatment.»
«We used the algorithms to identify typical molecular signatures
of stem cells [stemness signatures] that could help us understand
tumors and serve as predictors
of aggressiveness or clinical outcome.»
Adjusted relative risk ratios (RRR) and 95 % confidence intervals for the association between prostate cancer incidence and the scores
of adherence to Western, Prudent, and Mediterranean dietary patterns in MCC - Spain study by
tumor aggressiveness and extension.
Italian researches have demonstrated a better way
of determining the
aggressiveness of tumors in patients with advanced non-small cell lung cancer (NSCLC).
In a study presented in the featured clinical investigation article
of the November issue
of The Journal
of Nuclear Medicine, they used 18F - fluorodeoxyglucose (FDG) PET / CT imaging to show that the amount
of cell - free
tumor DNA circulating in the bloodstream correlates with
tumor metabolism (linked to cancer
aggressiveness), not
tumor burden (amount
of cancer in the body).
In their study published in The Journal
of Pathology, the team shows that
tumor relapse occurs when the body, in effect, mobilizes itself in favor
of the
tumor, causing recurrence
of the disease, increasing its
aggressiveness and creating metastases or
tumor spread.
Until now, scientists have failed to establish a link between the properties
of pancreatic cancer, such as its
aggressiveness, and changes, i.e. mutations, in the
tumor's genome.
«We also showed that as the number
of mutant KRAS copies increases, the
tumor's
aggressiveness and ability to metastasize also increases.»
GLUD1 and SLC25A13 have pivotal roles in nutritional stress and are associated with
tumor aggressiveness and poorer prognosis
of colorectal cancer.
«GLUD1 and SLC25A13 were associated with
tumor aggressiveness and poorer prognosis
of colorectal cancer.
Although CSs comprise only 2 % -5 %
of all uterine malignancies and 1 % -2 %
of all ovarian
tumors, they are responsible for a disproportionate number
of deaths due to their high biologic
aggressiveness and resistance to standard treatments, such as radiation and chemotherapy.
Areas surrounding
tumors and inflammations are usually slightly more acidic than areas surrounding healthy tissue, a phenomenon possibly linked to the
aggressiveness of tumors.
The
aggressiveness of a
tumor is determined partly by the properties
of the actual cancer cells, but also to a surprisingly large degree by the surrounding envi...
Whether and how to treat localized prostate cancer is thus a difficult decision, and depends largely upon an appraisal
of the
aggressiveness of the
tumor and the likelihood that the cancer will spread to other organs.
Blood clots lead to both destruction
of the healthy and
tumor tissue and hypoxia, a shortage
of oxygen that drives more
aggressiveness in the
tumor.
Aberrant expression
of TUBB3 has also been found in various
tumors of non-neural origin and can be used as a biomarker for cancer
aggressiveness and a marker for the tendency to respond poorly to chemotherapy.
Identification
of genes associated with local
aggressiveness and metastatic behavior in soft tissue
tumors.
Researchers have developed a breakthrough new method that uses current MRI technology to accurately identify the
aggressiveness of a
tumor without a biopsy
Determining the optimal treatment plan takes a number
of factors into consideration, including the patient's preferences, the type, number, location and
aggressiveness of the
tumor (s) as well as the overall health
of the patient.
Hypoxia - induced dedifferentiation
of tumor cells — a mechanism behind heterogeneity and
aggressiveness of solid
tumors
Important features
of XMRV biology include (1) tropism for a variety
of cell lines, including prostate cancer DU145 and LNCaP cells [27], [43], [48], and human neural cell types [57], (2) adaptations that promote growth in prostate epithelium and human - derived prostate cancer cell lines including an androgen response element in the promoter region [58] and downregulation
of APOBEC3G [59], and (3) cellular effects with potential oncogenic properties including increased
tumor aggressiveness mediated by downregulation
of p27 [60] and differential regulation
of several microRNAs [61].
Dr. Deppe suspected that this
tumor was causing the adrenal gland to secrete testosterone which was responsible for the inappropriate urination,
aggressiveness toward his housemate, and the development
of the tom cat jowls.
Reproductive disorders such as pyometra, mammary
tumors, testicular cancer, ovarian cancer, and prostate cancer are also reduced / prevented with neutering (reviewed in [2]-RRB- although neutering has been associated with increased risk or
aggressiveness of prostatic cancer [3 — 5].
Just as human
tumors are staged according to
aggressiveness and degree
of development (early, late, etc.), so are the
tumors found in cats.
Pathology reports also reveal the
aggressiveness of tumors and the likelihood that they have already moved or will move and threaten your pet's life.
The grade is an important factor in determining the rate
of aggressiveness of the
tumor.
Grade II
tumors are considered to be in between I and III in terms
of invasiveness and
aggressiveness.