Sentences with phrase «of tumor mass»

Treatment of malignant glioma using gene transfer modalities typically consists of surgical debulking of the tumor mass followed by the administration of the viral vectors into the brain tissue surrounding the tumor cavity.
Cancer stem - like cells (CSC) are a minor population of tumor mass and considered to have abilities of tumor initiation, differentiation, and chemoresistance (1).
In cancer, Myc levels and its power becomes overwhelming and the cells start to divide wildly and refuse to die, leading to rapid growth of a tumor mass.

Not exact matches

This is when the fertilized egg grows abnormally and the placenta becomes a mass of cysts, like a benign tumor.
Sternomastoid tumor of infancy (SMTI) is the most common cause of neck mass in the perinatal period.
Many biomarkers are available for estimating tumor mass, but a possibly more important aspect of a tumor's pathology is how aggressive it is and how fast it is growing.
Once the tumor was reduced to the size of a walnut, a surgeon could move in and remove the mass.
«Particularly in such patients with underlying CKD, our modeling results support the integration of renal tumor anatomic features at cross-sectional imaging into decision making for treatment of small renal masses and may be used to provide a patient - centered framework for selection of optimal candidates for ablative therapy,» Kang said.
With that knowledge, they screened more than four dozen monoclonal antibodies — unique agents that can stop cells from growing or forming tumors and can be mass produced — before finding two that block tumor creation in both types of cancer.
EM: Imaging such as MRIs or CT scans, which reveal the mass and volume of the tumor, can fool you sometimes: The patient gets a scan, goes on a therapy, and when they return in a month for a second imaging, the structure and size of the tumor haven't changed.
She even found evidence that the devils» immune systems were occasionally performing this interferon - gamma trick themselves: In some instances, tumor cells near the edge of the tumor, in close proximity to white blood cells, showed MHC antigens that cells farther within the tumor mass lacked.
The result can be the chaotic mass of cells called a tumor.)
For each patient, the suitable combination treatment could then be designed, which, in the first step, would turn the variety of different tumor cells into a mass of cancer cells of the same type.
The team's recent study in mice has found that the treatment reduced the mass of ovarian cancer tumors and was more effective at suppressing tumor growth than chemotherapy.
«Radioimmunotherapy not only worked against these cancers but, in addition, the radioactivity was confined entirely to the tumor masses, leaving healthy tissues undamaged,» said senior study co-author Ekaterina Dadachova, an associate professor of nuclear medicine and of microbiology and immunology at Einstein.
«Another model is punctuated evolution in which CNAs are acquired in short bursts of crisis, followed by stable clonal expansion that form the tumor mass.
Tumors in other tissues are generally more solid, which can physically impede the ability of T - cells to penetrate into the mass of the tumor.
Researchers found the gene therapy approach had stronger results when used in combination with either depletion of immunosuppressive cells from the tumor mass or with immune checkpoint blockade.
This process requires a fundamental change in the character of cells within the primary tumor, insofar as members of a localized cell mass must be converted into actively migrating cells that invade into the surrounding tissue and blood vessels, and finally settle in distant tissues.
Ding said recent advances in a technology called mass spectrometry and in techniques to analyze massive quantities of data have made complex studies of the proteins in tumor cells possible.
Senior co-author of the study, Andrew Sloan, MD, Medical Director, Brain Tumor and Neuro - Oncology Center at University Hospitals Cleveland Medical Center, observed that GBMs typically have two radiologically distinct regions on MRI: The enhancing mass and the necrotic core.
It is generally believed that a series of mutations in multiple genes are needed for cancer cells to become metastatic; however, recent cancer stem cell theory, which still remains as a hypothesis, predicts that metastatic tumor cells are, by definition, cancer stem cells and that these cells may exist in tumor mass even at an early stage.
«Researchers find a likely cause of inflammatory myofibroblastic tumors: Finding that may lead to new treatments for rare masses of immune cells.»
Thus, in a panel of breast cancer samples, we identified tumor cells that did not form part of the bulk tumor mass, but instead were interspersed within the adjacent stroma — as if forming the forefront of cancer cell invasion.
Together, these results suggested that EMT contributes to the establishment of a small cell subpopulation in malignant tumors; this population is then capable of driving the regeneration of the tumor, even when the bulk tumor cell mass is destroyed by therapeutic regimens.
Selectivity of the therapeutic approach is achieved by producing an enzyme called E. coli purine nucleoside phosphorylase (PNP) directly within tumor cells and using the enzyme to generate novel chemotherapy in the tumor mass itself.
Therefore several trials previous published have as an exclusion criterion atelectasis, pleural effusion and tumor mass more than 5 cm of diameter.8 The rest of the criteria remain the same as in the case of intravenous infusion, renal function, blood values and performance status have to be appropriate according to the NCCN guidelines.38 Moreover; the administered drug has to be safe in order to be provided as aerosol, several chemotherapy agents have been reported to be toxic for the lung parenchyma.
When Laura Moreno was diagnosed with a low - lying mass in her rectum, she turned to Irving Waxman, MD, who performed an advanced endoscopic procedure that completely removed the tumor without the potentially dangerous complications of surgery.
Optical quantification of cellular mass, volume, and density of circulating tumor cells identified in an ovarian cancer patient.
Therefore the dosage of administration has to change at it has been previously observed with other treatment modalities such as; inhaled insulin.35, 37 A major obstacle regarding the distribution of aerosol within the airways is atelectasis, tumor mass or pleural effusion.
It reinforces the notion that tumors (and TNBC in particular) are not a homogeneous mass of identical cells, but a collection of distinct sub-populations of cells evolving somewhat independently of one another.
In this fashion, they derive a signal from the tumor cells proportional to tumor mass which arises spontaneously in vivo in the accurate setting of the lung and from the accurate genetic lesions found in human non-small cell lung cancer (NSCLC).
At the Solid Tumor Oncology Program, part of C.S. Mott Children's Hospital at the University of Michigan, we provide comprehensive, multidisciplinary care for children with Wilm's tumor and other renal masses or kidney tuTumor Oncology Program, part of C.S. Mott Children's Hospital at the University of Michigan, we provide comprehensive, multidisciplinary care for children with Wilm's tumor and other renal masses or kidney tutumor and other renal masses or kidney tumors.
Application of doubly engineered neural stem cells proves to be a specific and highly effective method of removing remnant tumor mass after surgery
Germ cell tumors are masses of tissue formed by immature cells that normally would have developed into mature eggs (in a female) or sperm (in a male).
A tumor is an abnormal lump or mass of tissue.
Artificially increasing the levels of upd, results in tumor - like masses of stem cells.
Technical coordinator of a national convention in France involving industry and universities on the same subject Since 1992: Organizer of a cycle of international conferences on «Heavy scintillators for scientific and industrial applications» First one in Chamonix, France in 1992 (200 participants), 9th one in Winston Salem (NC, USA) in 2007 (300 participants) 1994 - 2007: As Technical coordinator of the CMS electromagnetic calorimeter at the LHC Large Hadron Collider, responsible for the technical development and the mass production of 76» 000 Lead Tungstate crystals (100 tons) 1994 - 2000: Organizer of the development and mass production organization of Lutetium Aluminum perovskite crystals, in particular for PET scanner applications Since 2000: Strong involvement in the development of dedicated breast imaging camera combining several modalities for a multiparametric evaluation of breast tumors (anatomic, structural and functional) Since 2002: Feasibility study and setting - up of an international medical imaging research centre, presently being built in Marseille (Cerimed)
This microscopic photo shows tumor cells from a fine needle aspiration cytology smear of a liver mass.
The presence of NSCs within the tumor mass was confirmed by detection of v - myc DNA using nested PCR.
As fast growing tumor mass lacks a functioning lymphatic system, clearance of these nanoparticles is limited and further enhances the accumulation.
Intravenously - injected parental and transduced HB1.F3 NSCs were detected within the tumor mass of each treated animal by immunohistochemistry.
«Because of the size of the tumor relative to my total breast mass, it would have been very disfiguring to take the whole tumor out [and not remove the breast too].
«consumption of abundant alkaline - forming foods can result in improvement in bone mineral density (BMD) and muscle mass, protection from chronic illnesses, reduced tumor - cell invasion and metastasis, and effective excretion of toxins from the body.
The doctor reading your mammogram will be looking for different types of breast changes, such as small white spots called calcifications, lumps or tumors called masses, and other suspicious areas that could be signs of cancer.
Although this tumor was thankfully benign, it's important to familiarize yourself with the symptoms of ovarian cancer — especially since most signs of the illness aren't as obvious as a large, fast - growing mass.
The medical team simultaneously removed the tumor and reconstructed the skin on her abdomen that had been stretched by the mass, minimizing the number of times she needed to go under the knife.
These masses are benign tumors of basal cell origin (meaning they do not metastasize), and they are the most common skin tumors of guinea pigs.
Cancer shortens the lives of nearly half of all dogs and cats in the U.S. Cancer in pets occurs when the body's immune system can not stop cells from replicating at an abnormally fast, disorderly pace and forming a mass known as a tumor.
Generally speaking, there are a small number of life - threatening tumors that can spread in the body, a large number of masses that cause damage inside the mouth, and a lot of swellings that are caused by inflammation and can look like other masses.
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