Sentences with phrase «of tumor progression»

But questions remained about the timing and course of tumor progression.

The loss of let - 7, the authors argue, could be seen as one crucial step in this process of tumor progression.

Patients who responded to methylnaltrexone also had significantly fewer reports of tumor progression (7.6 percent) compared to those who did not respond (22 percent) or who took the placebo (25.4 percent), based on physician reports of adverse events.

During the last three years the Spanish Consortium for the Study of the Genome of the Chronic Lymphatic Leukemia, where the researchers of the present study already collaborate, has sequenced the genome of hundreds of patients with the more common leukemia in our society, identifying new mechanisms of tumor progression and new therapeutic targets.

The anxiety and uncertainty that men who choose active surveillance experience when diagnosed with prostate cancer causes one in four to receive definitive therapies within one to three years, even when there is no sign of tumor progression.

«Clonal evolution is a major driver of tumor progression and drug resistance.

Her work seeks to elucidate the mechanisms and pathways underlying the interaction between the immune system and cancer using mouse models that recapitulate the coevolution of tumor progression and the antitumor immune response.

A range of potential targets of miR - 7 were reported including EGFR, IRS - 1, PAK - 1, RAF - 1, and SATB1 that are involved in key signaling of tumor progression (23, 25).

The Nefedova laboratory focuses on understanding the role of bone marrow microenvironment in regulation of tumor progression and therapy resistance.

These two aspects of tumor progression (hypoxia and reoxygenation) cooperate to provide growth advantages essential for the progressive development of aggressive tumors [21].

The laboratory currently pursues four integrated research objectives: 1) Defining how dynamic regulation of adhesion and migration controls metastasis, 2) Identification and characterization of the metastatic cell populations within a primary tumor, 3) Experimental modeling of metastasis in a clinically relevant manner, and 4) clinical implementation of molecular markers of migration as biomarkers of tumor progression and metastasis.

Identify an alternate paradigm of tumor progression whereby metastases arise from cells that disseminate from the primary site at any stage of primary tumor progression and evolve independent from the primary tumor (i.e., parallel progression models).

Nowell went on to study chromosomal changes in other tumors, and this led him to advance the theory of the clonal evolution of tumor progression.

Patients with advanced cancers who took a drug designed to relieve constipation caused by pain killers lived longer and had fewer reports of tumor progression than cancer patients who did not receive the drug, according to results presented Oct. 27 at the 2015 meeting of the American Society of Anesthesiologists in San Diego.

«We are not precisely sure why methylnaltrexone was associated with fewer reports of tumor progression and longer survival in our patients,» Janku said.

October 27, 2015 Drug for digestive problem can extend survival for many advanced cancer patients Patients with advanced cancers who took a drug designed to relieve constipation caused by pain killers lived longer and had fewer reports of tumor progression than cancer patients who did not receive the drug, according to results presented October 27 at the 2015 meeting of the American Society of Anesthesiologists in San Diego.

Patients with advanced cancers who took a drug designed to relieve constipation caused by pain killers lived longer and had fewer reports of tumor progression than cancer patients who did not receive the drug, according to results presented October 27 at the 2015 meeting of the American Society of Anesthesiologists in San Diego.