Sentences with phrase «of tumor reduction»

In the group that received targeted treatment for ALK - positive lung cancer, each category of tumor reduction was associated with corresponding gains in PFS and OS.

Not exact matches

Amazingly, with the introduction of only 25 % coconut flour in the form of cake there exhibited a dramatic reduction in tumor growth.

The result is a sharp reduction in the growth and spread of tumors, according to Moss and Singleton's findings.

Injecting spores of C. novyi into dogs resulted in rapid reduction of tumor sizes, and even completely eradicated tumors in three of 16 trial dogs.

The study demonstrated a trend toward a reduction in the incidence of tumor recurrence in patients who had pelvic RT..

The reduction in the number of potentially unnecessary biopsies appears to have occurred at the cost of detecting fewer intermediate risk PCa tumors.

Benefits include reduction of tumor burden, delayed cancer progression, and overall improvement in survival in some cases.

Currently, Dr. Ocal is trying to find the best combination of available drugs that generates the largest reduction in tumor growth early on.

In a mouse model of melanoma, blocking this pathway resulted in reduction of tumor growth.

The more robust tumor reduction and suppression of escape pathways possible with PMILs might enable curative surgery or improve the outcome of chemotherapy to enhance patient survival.

In two mouse models of pancreatic cancer, a single treatment consisting of intravenous delivery of the PMILs followed by localized delivery of near - infrared light to the tumor site via optical fibers resulted in significantly greater reduction in tumor size than did either treatment with XL184 or PDT with BPD alone.

«A single injection of our nanoparticles completely eradicated the tumors in five of the seven treated animals and the remaining animals had significant tumor reduction compared to the controls,» Farokhzad says.

A team led by principal investigator Donald M. O'Rourke, MD, an associate professor of Neurosurgery at Penn, and Marcela Maus, MD, PhD, showed that CART - EGFRvIII cells had an acceptable safety profile, crossed the blood - brain barrier, infiltrated the tumor, and prompted an immune response, resulting in reduction of the EGFRvIII tumor antigen in GBM cells.

Injections of antibody molecules that block CD47 from interacting with SIRPA are already being tried in the clinic based on observations of some reduction in the sizes of tumors in mouse models.

Recent studies of somatic mutations in tumor cells revealed a fascinating phenomenon: a reduction in the mutation rate of highly transcribed regions, likely attributed to the fidelity conferred by transcription - coupled DNA repair mechanisms.

And in the trial, slightly more than half of the 26 Keytruda - treated patients had a significant reduction in their tumors.

The changes included reductions in the use and dose of radiation therapy and chemotherapy drugs called anthracyclines for treatment of acute lymphoblastic leukemia (ALL), Hodgkin lymphoma and Wilms tumor, a cancer of the kidneys.

Two tumors (4 %) had a partial response, defined as reduction in tumor volume of more than 30 percent.

Excitingly, a single dose of any of the three NK cell populations assessed led to a significant reduction in tumor burden, although the iPSC ‐ derived NK group demonstrating a trend toward overall better activity.

Administration of this reagent into mice bearing human AL tumors or those with systemic AA deposits resulted in marked reduction in amyloid burden with no evidence of toxicity in the animals.

«This is especially valuable in cancer treatment, where targeted treatment to tumor cells, and the reduction of lethal effects in normal cells, is so critical,» she added.

Rashid OM, Nagahashi M, Ramachandran S, Yamada A, Graham L, Milstien S, Spiegel S, Bear HD, Takabe K. Resection of the Primary Tumor Improves Survival in Metastatic Breast Cancer by Reduction of Overall Tumor Burden.

Therapy of doxorubicin resistant MX - 1 tumors with MIA - 602 or combination led to significant (P < 0.05) reduction in MDR1 and NANOG gene expression relative to controls.

At the American Society of Clinical Oncology (ASCO) 2017 Annual Meeting, we presented monotherapy data of nine patients who received G100 with radiation (no pembrolizumab) that showed 100 % DCR rate, with 44 % of the patients achieved a partial response (PR) based on WHO criteria, which requires at least a 50 % tumor reduction to qualify as a PR.

Silencing of the enzyme stimulated vessel formation, but paradoxically resulted in a profound reduction of tumor growth; an effect that relies on the anti-proliferative nature of the TGFβ signaling pathway, in a largely HIF1α - independent manner (Klotzsche - von Ameln et al., Cancer Res., 2011 and Cancer Biol Ther., 2012).

Researchers at The McDonnell Genome Institute at the School of Medicine have co-led a study on breast tumors — before and after hormone reduction therapy.

«We found a strong reduction in the risk of estrogen - receptor - negative [ER --RSB- breast cancer in particular, which is exciting because that type of tumor, while rarer than estrogen - receptor - positive [ER +] tumors, tends to be aggressive.»

Possible reduction in certain types of cancer: «It appears to work primarily by blocking the growth and metastatic spread of tumors, controlling the cell cycle, and by reducing inflammation.»

Another study published in the Journal of Cancer Science and Therapy found that after just 30 days of infrared treatment, tumor - infected mice saw up to 86 % reductions!

Extract of asparagus administered orally in doses of 250 and 500 mg / kg body weight for 10 days caused a significant reduction in tumor volume and tumor cell count.

Tests have shown that it helps in tumor reduction and in the production of healthy heart cells.

Other uses for Vitamin K include but are not limited to: aiding in the absorption of calcium in bone, aiding in the reduction of excessive menstrual flow, stopping some cancer tumors, overcoming the inability to absorb vitamins, and maintaining vitality and longevity.

While tumor growth was reduced in both sets of mice, the tumors of the mice treated with both progesterone and Tamoxifen experienced the greatest growth reduction.

Rats that consumed 5 - 10 percent of their diet as freeze - dried black raspberries and strawberries showed dramatic reductions in the growth of precancerous cells and tumor progression, the researchers found.

Curcumin is a powerful antioxidant agent that has been directly linked with a reduction in colon cancer cells and is also a direct inhibitor of a protein that is essential for tumor growth.

Additionally, two randomized, placebo - controlled trials found no significant reduction in the incidence of colon tumor indicators among subjects who supplemented their diet with wheat bran or consumed high fiber diets (MacLennan et al., 1995; McKeown - Eyssen et al., 1994).

• Reduction of risk for mammary tumors • Elimination of risk for pyometra • Elimination of heat cycle - related behaviors

Neutered dogs have many health benefits, including a reduction in testicular tumors, fewer prostate related diseases, a reduction of perianal tumors, and a smaller number of hernias.

But a recent discovery in the world of holistic medicine has shown very promising results in the reduction and destruction of such tumors...

There also have been some studies that show that this product helps with the prevention of cancer and tumor reductions in dogs.

Neutering benefits include protection from prostatitis and testicular tumors, as well as reduction of undesirable behaviors, including aggression toward other male dogs, desire to roam, urine marking and inappropriate mounting.