Single - cell DNA solid tumor profiling enables high resolution of the genomic diversity in a
variety of tumor types.
One of the confusing issues with tumor submission is that specific
diagnosis of the tumor type and submitting a sample to the repository are two different submissions.
The selection of a radiation dose is based on
considerations of tumor type, tumor location, and on the tolerance of the normal tissues surrounding the tumor.
This candidate new drug, a first - in - its - class, shows activity against a broad
range of tumor types in mice and appears safe at this stage.»
The Radiation Oncology Service at Ohio State's Veterinary Medical Center provides radiation therapy for a variety
of tumor types in both large and small animal patients.
The median time to response was 1.8 months, and responses occurred
regardless of tumor type, patient age, or specific TRK fusion characteristics.
This separation may not be restricted to ovarian cancer, or to the NCI60 panel of tumor cells, they suggest, but could apply to a
multitude of tumor types.
«This analysis of a large population of patients across a broad
scope of tumor types suggests that avelumab was associated with an incidence of immune - related adverse events that is consistent with that of other immune checkpoint inhibitors.»
Biopsy provides a complete
picture of tumor type and behavior and allows us to determine if the surgical margins are clear of cancer cells.
During her residency, Dr. Fritz lectured nationally on a
spectrum of tumor types and was awarded a research certificate on osteosarcoma (bone cancer).
Together these reports suggest that VEGF plays an important role in the
progression of these tumor types in the dog and as such represents a potential therapeutic target.
While the initial tests with the chip have focused on breast cancer, Panchapakesan says the device could be set up to detect a wide
range of tumor types, and plans are already in the works for development of an advanced device as well as testing for other cancer types, including lung and pancreas cancer.
Revving up the immune system to combat a wide
variety of tumor types may take cancer therapy in a new direction, says Khaled Barakat, a computational scientist at the University of Alberta in Canada, who was not involved in the study.
If such an indel is found in this gene, Ding and her colleagues suggest a patient may benefit from an EFGR inhibitor, such as erlotinib,
regardless of the tumor type.
In addition to their PCR - based tests, his group is also designing liquid biopsies that use next - generation sequencing (NGS) to identify a broader range
of tumor types and mutations.
In humans, an increased genetic signature of these cells correlated with better outcomes in a variety
of tumor types.
A relatively new biomarker called prostate - specific membrane antigen (PSMA) is the bullseye for three new magnetic resonance imaging (MRI) agents that bind to the protein in not only prostate cancer, but a range
of tumor types, according to research unveiled at the 2015 annual meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).
Baltimore, Md. (Embargoed until 12:30 pm EDT on Monday, June 8)-- A relatively new biomarker called prostate - specific membrane antigen (PSMA) is the bullseye for three new magnetic resonance imaging (MRI) agents that bind to the protein in not only prostate cancer, but a range
of tumor types, according to research unveiled at the 2015 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).
Because the toxin does not target the tumor cells themselves but rather the host - derived blood vessel cells, the strategy could be efficacious for a wide range
of tumor types, the NIH team notes.
The turnkey functionality of this closed - system sorter decreases production time and offers the prospect of treating larger patient cohorts for a broader range
of tumor types, requiring reduced personnel and resources.
The results of SEngine's functional screening assay — which is performed on a wide variety of tumor types
The results of SEngine's functional screening assay — which is performed on a wide variety
of tumor types — have matriculated into an extensive and rich dataset which facilitates a novel method of target discovery within a previously untargeted area of the human genome.
The overexpression of GLI2 has been identified in a variety
of tumor types, and yet questions remain regarding the mechanisms of this overexpression.