Sentences with phrase «of tumor vasculature»

The NAVBO Meritorious Awards Committee and Council is pleased to announce the selection of Rakesh K. Jain, Ph.D., as the 2018 recipient of the Earl P. Benditt Award, in recognition of his numerous contributions to our understanding of the unique characteristics of tumor vasculature.

The occurrence of reoxygenation following hypoxic exposures of various degrees is inherent in the dynamic nature of the tumor vasculature [43, 44].

Not exact matches

«Because the particles are so small, if they happen to reach the tumor site they have a chance of penetrating through the blood vessel wall because the vasculature of tumors is usually leaky.»

Unfortunately, approximately 85 percent of cancer patients are ineligible for surgery at the time of diagnosis, either because the tumor is entwined in critical vasculature or the disease has progressed too far.

«The enhancing effect was not seen in a patient tumor sample with a low level of NRP - 1 expression on the vasculature.

And because tumors typically have a leaky, ill - formed vasculature, the particles tend to leak out at the site of cancer tissue and be picked up and internalized inside tumor cells.

Targeting tumor endothelial marker 8 in the tumor vasculature of colorectal carcinomas in mice.

Early observations suggesting that the virus might attack cancer in part by damaging blood vessels that feed tumor growth led the SillaJen team to strike up a collaboration with McDonald, an expert in tumor vasculature, to investigate the virus's mechanism of action in animal models.

The irregular vasculature of solid tumors creates hypoxic regions, which are characterized by cyclic periods of hypoxia and reoxygenation.

The NCI's website describes active targeting as «the targeting of nanoparticles to tumor cells, microenvironment or vasculature, as well as directed delivery to intracellular compartments, through nanoparticle surface modification with small molecules, antibodies, affibodies, peptides or aptamers.»

Dr. Jain's nominators note that, in sum, his work has provided ``... unprecedented molecular, cellular, anatomical and functional insights into the vascular pathophysiology of tumors, for proposing the seminal hypothesis that antiangiogenic therapy can «normalize» the aberrant vasculature and microenvironment of tumors and thereby improve both delivery and efficacy of treatment of solid tumors.»

This would bypass the potential adverse effects of hypoxia on the CSC fraction while limiting tumor progression due to the general vasculature effects.

The scan revealed large adrenal tumors present on both sides without significant evidence of invasion into the vasculature or surrounding structures.

Interventional procedures — including cardiac pacing, balloon valvuloplasty, transcatheter PDA closure, tracheal stenting, urethral stenting for cancerous obstructions, ureteral stenting from both malignant (cancer) and benign (stones, stricture) causes, intrahepatic portosystemic shunt closure, nasopharyngeal stenting, arterial embolization or chemoembolization for bleeding or to slow tumor growth, arterial coiling of guttural pouch mycosis, foreign body retrieval from the GI tract, respiratory tract, or vasculature, etc