The talk addresses paradigms
of uncertain risk, and how to act under conditions of uncertainty.
By choosing organic, one hopes to shift exposures from a range
of uncertain risk to more of a range of negligible risk, but even if all we had to eat were the most pesticide - laden of conventional produce, there is a clear consensus in the scientific community that the health benefits from consuming fruits and vegetables outweigh any potential risks from pesticide residues.
You may prefer to choose a US travel insurance plan depending on your pocket size; however, try to make sure you have coverage against all kinds
of uncertain risks.
Not exact matches
«These (
risks) include the possibility
of a sharp tightening
of global financial conditions, growing trade tensions, and geopolitical strains — while the outlook for oil prices remains subdued and highly
uncertain,» the report said.
Actual results and the timing
of events could differ materially from those anticipated in the forward - looking statements due to these
risks and uncertainties as well as other factors, which include, without limitation: the
uncertain timing
of, and
risks relating to, the executive search process;
risks related to the potential failure
of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies
of eptinezumab sufficient to achieve a positive completion; the availability
of data at the expected times; the clinical, therapeutic and commercial value
of eptinezumab;
risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements;
risks and uncertainties relating to the manufacture
of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights
of others; the
uncertain timing and level
of expenses associated with Alder's development and commercialization activities; the sufficiency
of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «
Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.
While credit
risk might seem like a bad idea with the U.S. economy still weak and the rest
of the world looking equally
uncertain, high - yield bonds do offer bigger returns than government and investment - grade bonds.
All forward - looking information is inherently
uncertain and subject to a variety
of assumptions,
risks and uncertainties, including changes in personnel, competitive
risks and the availability
of financing.
Despite an
uncertain economy, more
of our students are willing to take the
risk of starting up new enterprises,» adds Sanghvi.
Although shareholders have yet to approve the deal, the banks would «re-pay shares at a pre-defined value in next few months, avoiding the
risk of uncertain evolution
of huge claims by shareholders and clients,» Maria Paola Toschi, global market strategist at JPMorgan Asset Management, told CNBC on Tuesday via email.
«We live in an
uncertain world and face not only the
risks of the known unknowns but also the unknown unknowns — the ones that we don't know we don't know,» he said.
«These are
uncertain times again and there is a
risk of another global downturn,» said Stephen Webster, chief European economist at 4CAST.
Analysts said the move represented a good use
of the bank's excess cash, but warned it carried some
risks given Britain's
uncertain economic outlook following the country's vote to leave the European Union in June.
These
risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the
risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an
uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect
of lowering prices or reducing the number
of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the
risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other
risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
The gamble for a CEO is a
risk that must be taken when aspiring to move the business forward, and you must accept the
uncertain future
of your bet in that it could also result in costing your job.
What makes climate change different, they say, is that there are five new variables:
uncertain and fragmented environmental legislation and regulations; the reactions
of capital and insurance markets to emerging business opportunities (and matching
risks) posed by climate change; stakeholder activism; pending litigation and the rapidly evolving scientific debate over proper responses to climate change.
Moreover, our international expansion efforts have resulted and will continue to result in increased costs and are subject to a variety
of risks, including increased competition,
uncertain enforcement
of our intellectual property rights, more complex distribution logistics, and the complexity
of compliance with foreign laws and regulations.
The limitations
of macroprudential policies reflect the potential for
risks to emerge outside sectors subject to regulation, the potential for supervision and regulation to miss emerging
risks, the
uncertain efficacy
of new macroprudential tools such as a countercyclical capital buffer, and the potential for such policy steps to be delayed or to lack public support.14 Given such limitations, adjustments in monetary policy may, at times, be needed to curb
risks to financial stability.15
Although the path for negotiations on the United Kingdom's departure from the European Union (EU) remains
uncertain, the French presidential election result has removed another potential political
risk that may have been holding back activity in some parts
of Europe.
Extra
risk for negligible /
uncertain extra reward that doesn't fit into an investing strategy isn't really part
of the passive investing playbook.
Before any User decides to purchase, hold and use digital tokens, the User should make certain that he fully understood all
risks, including but not limited to
risk of losing access to tokens due to loss
of private key (s),
risks associated with the ethereum platform protocol,
risk of hacking and security weaknesses,
risk of uninsured losses,
risks associated with
uncertain regulations and enforcement actions.
Meanwhile, US stocks have been regularly charting new highs and appear to be fundamentally underpricing the
risks associated with one
of the most
uncertain and divisive political climates
of our lifetime.
Going into 2013, the short - term outlook is
uncertain, however, with mounting sociopolitical and security
risks in certain countries in the Middle East overshadowing the economic and capital market resilience
of the region's oil - rich economies, he notes, most notably Saudi Arabia, Qatar and the United Arab Emirates.
We saw considerably reduced trading in TSX and TSXV - listed securities; many investors were left
uncertain about the status
of their orders; and there was a real
risk of mispriced trades.
With these reservations we might well be
of the opinion that the Church in Germany, and not only there, is, on the whole, still tempted to defend old conservative positions rather than to surrender them in order to prepare even now for an inevitable future, despite some conciliar courage to start anew and
risk an
uncertain future.
That and Spong's moving testimony — «The only reward Christ offers, I believe, is the Christian life
of openness, vulnerability, expansion,
risk, wholeness, love» — scarcely bespeak an
uncertain, «dishonest» faith.
Results: In the two groups
uncertain about receiving intercessory prayer, complications occurred in 52 % (315/604)
of patients who received intercessory prayer versus 51 % (304/597)
of those who did not (relative
risk 1.02, 95 % confidence interval 0.92 - 1.15).
Complications occurred in 59 % (352/601)
of patients certain
of receiving intercessory prayer compared with the 52 % (315/604)
of those
uncertain of receiving intercessory prayer (relative
risk 1.14, 95 % confidence interval 1.02 - 1.28).
The problem is that this process is unprecedented, will take considerable time to complete and it outcome is necessarily
uncertain — points
of risk were spelled out pretty clearly in the latest bidder statement Murray Goulburn offered the market on Monday.
In turn, their hopes
of finishing in the top four and securing qualification for the Champions League are at real
risk and coupled with Wenger's future still being
uncertain, it has led to criticism from supporters and protests against him staying on beyond this season.
With the futures
of De Gea, Valdes and now Lindegaard
uncertain, United are running the
risk of being left with only summer arrival Romero to lead in between the posts at the Theatre
of Dreams.
Meanwhile, Calciomercato claim that two strikers struggling this season could be at
risk of being offloaded this summer, with Andre Silva and Nikola Kalinic facing
uncertain futures.
Will Bilic, given his
uncertain position, take the
risk of blooding any young players?
Not only was that assertion completely at odds with the
uncertain state
of the existing science, but it was contradicted by the study itself, in which Dr. McKee and her colleagues acknowledged that several other factors, besides prior participation in football, may influence CTE
risk and disease severity, including factors other than cumulative hits to the head, and admitted that it was even «unclear» what roles concussions and repetitive subconcussive hits play in CTE
risk, disease severity, and progression.
... [D] isclosure by the [provider] to the patient
of adequate clear information about the patient's diagnosis; the alternatives available to treat the patient's problem, including surgical and nonsurgical management; the benefits and
risks of each alternative, including nonintervention... and a frank explanation
of those factors about which the medical profession, and the individual [provider] in particular, are
uncertain and can not provide guarantees...
You can share this article to all moms out there who are facing the same
uncertain thoughts in connection to
risks of baby sleeping face down!
The American College
of Obstetricians and Gynecologists (ACOG) issued new recommendations to help reduce the use
of many common labor and birth interventions that offer limited or
uncertain benefit to low -
risk women.
Sleeping position - While it's still
uncertain, some researchers believe that sleeping in a supine position (on your back) may be associated with an increased
risk of stillbirth.
Many politicians and climate reports now talk about
risk, which works for some audiences — particularly in the business sector — who deal every day with assessing investment, insurance and other types
of uncertain outcomes.
To go back in history, the French Revolution
of 1789 represented an
uncertain event to the other European powers; its outward expansion constituted a
risk for them.
«We are engaging an interdisciplinary team to figure out how to improve resilience and preparedness in these situations where the
risks are ongoing and the exact nature
of the hazards that people are facing is
uncertain.»
Since 1994, dozens more genes have been found that increase a woman's
risk of hereditary breast cancer, but by how much is
uncertain, confounding already complicated issues in genetic testing and counseling.
The results for breast cancer are in line with previous research, but the true effect
of alcohol on
risk of ischaemic heart disease remains
uncertain, say the editorial authors.
The study estimates that new nuclear plants carry a heavy
risk premium because
of uncertain construction costs.
The earlier Cochrane analysis found Tamiflu cut the
risk of complications by 67 per cent, but the new one cuts this to 45 per cent, although the finding is statistically
uncertain because
of the much smaller sample size.
That meant the balance
of risk and harm from HRT was still
uncertain, they said, and it was ethical to keep enrolling women provided they were fully informed about the
risks.
But researchers are
uncertain if smoking induces those abnormalities or if they already exist and contribute to
risk of nicotine addiction.
«Limiting the use
of electronic fetal monitoring to the very highest
risk labours may be justifiable, but even then the balance
of benefits and harms is
uncertain,» he adds.
Until now, the
risks of this exposure known as «third hand tobacco smoke» have been highly
uncertain and not considered in public policy.
«The
risk of losing funds stored at exchanges is real but uncertain,» write Moore and Christin in «Beware the Middleman: Empirical Analysis of Bitcoin - Exchange Risk,» which was invited for presentation at the 17th International Financial Cryptography and Data Security Conference held in Okinawa, Japan, April 1
risk of losing funds stored at exchanges is real but
uncertain,» write Moore and Christin in «Beware the Middleman: Empirical Analysis
of Bitcoin - Exchange
Risk,» which was invited for presentation at the 17th International Financial Cryptography and Data Security Conference held in Okinawa, Japan, April 1
Risk,» which was invited for presentation at the 17th International Financial Cryptography and Data Security Conference held in Okinawa, Japan, April 1 - 5.
COFFEE BREAK Drinking coffee has a number
of health benefits that may outweigh its
uncertain cancer
risks, studies have shown.