Routine investigations — semen analysis, ovulation tests, ultrasound examination — will fail to find a clinical explanation in many of these cases, and the
treatment of this unexplained infertility remains a challenge.
Chrousos thinks a potential
cause of unexplained infertility or recurring early miscarriages in women might be due to a lack of CRH to prevent immune rejection.
«Although such differences may be a function of the large sample size and thus not clinically relevant, our findings suggest that use of ICSI may improve fertilization rates but not implantation or pregnancy rates in the
setting of unexplained infertility, advanced maternal age, and low oocyte [a cell from which an egg develops] yield,» the authors write.
Aboulghar M, Mansour R, Serour G, Abdrazek A, Amin Y, Rhodes C. Controlled ovarian hyperstimulation and intrauterine insemination for
treatment of unexplained infertility should be limited to a maximum of three trials.
My wife and I suffered three years
of unexplained infertility — disappointment was our very close friend during that time.
After two years
of unexplained infertility I finally surprise got pregnant with my first, and surprise got hooked up to an IV with constant fluids and meds and surprise could not work the entire time and felt like death most of my pregnancy.
Based on the above, it seems logical to conclude that improvement in pelvic blood circulation might be beneficial in the treatment
of unexplained infertility.